当前位置： SCI文献检索 > Deutsches Arzteblatt International期刊下所有文献 > Osteoporotic Fractures of the Thoracic and Lumbar Vertebra: Diagnosis and Conservative Treatment-A Systematic Review.

Osteoporotic Fractures of the Thoracic and Lumbar Vertebra: Diagnosis and Conservative Treatment-A Systematic Review.

Abstract：

BACKGROUND:The prevalence of osteoporotic vertebral body fractures in Europe is 18-26%. Although most of these injuries can be treated conservatively, the underlying concepts have not been defined clearly or uniformly. In this article, we present the current state of the evidence on the diagnosis and conservative treatment of osteoporotic fractures of the thoracic and lumbar vertebrae. METHODS:A systematic review of the literature up to May 2020 was carried out in the PubMed and Web of Science Core Collection databases. 549 articles were identified, of which 36 were suitable for inclusion in the review. Articles were sought in the areas of diagnosis, provision of physical aids, pharmacotherapy, physiotherapy, and treatments from the realm of alternative medicine. RESULTS:The primary diagnostic technique was conventional x-ray in two planes (with the patient standing, if possible), which had 51.3% sensitivity and 75% specificity. If a fracture was suspected, magnetic resonance imaging (MRI) of the entire spine and regional computed tomography (CT) were carried out. The overall state of the evidence on treatment is poor; the best available evidence is for exercise therapy and physiotherapy, which are supported by three level I and four level II studies. Improvements were seen mainly in mobility and a reduced fear of falling. The use of an active orthosis can be useful as well. No evidence was found on the use of drugs or alternative medicine exclusively in the conservative treatment of osteoporotic vertebral body fractures. CONCLUSION:It is reasonable to evaluate instability with imaging repeatedly, at regular intervals, over a period of six months. There is still a lack of reliable data on the optimal intensity and duration of physiotherapy, and on the use of orthoses.

journal_name

Dtsch Arztebl Int

journal_title

Deutsches Arzteblatt international

authors

Spiegl U,Bork H,Grüninger S,Maus U,Osterhoff G,J Scheyerer M,Pieroh P,Schnoor J,Heyde CE,Schnake KJ

doi

10.3238/arztebl.m2021.0295

subject

Has Abstract

pub_date

2021-10-08 00:00:00

issue

Forthcoming

issn

1866-0452

pii

arztebl.m2021.0295

pub_type

杂志文章

相关文献

Deutsches Arzteblatt International文献大全
  • Cowpox virus infection in pet rat owners: not always immediately recognized.

    abstract：:Cryptosporidium parvum are protozoan parasites responsible for outbreaks of gastrointestinal disease worldwide. Within the apical complex of this organism reside numerous vesicular secretory organelles and their discharge has been identified as essential for sporozoite motility, cell attachment and penetration. Tradit...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章

    doi：10.3238/arztebl.2009.0329

    authors： Becker C,Kurth A,Hessler F,Kramp H,Gokel M,Hoffmann R,Kuczka A,Nitsche A

    更新日期：2009-05-01 00:00:00

  • Implementation and effects of Germany's minimum volume regulations: results of the accompanying research.

    abstract：OBJECTIVE:To assess the association between smoking onset and exposure to movie smoking according to character type. METHODS:A longitudinal, random-digit-dial telephone survey of 6522 US adolescents was performed with movie exposure assessed at 4 time points over 24 months. Adolescents were asked whether they had seen...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章

    doi：10.3238/arztebl.2008.0890

    authors： Geraedts M,de Cruppé W,Blum K,Ohmann C

    更新日期：2008-12-01 00:00:00

  • Prostatitis and male pelvic pain syndrome: diagnosis and treatment.

    abstract：: Cigarette smoking is a major risk factor in the development of various lung diseases, including pulmonary emphysema, pulmonary fibrosis, and lung cancer. The mechanisms of these diseases include alterations in alveolar epithelial cells, which are essential in the maintenance of normal alveolar architecture and functi...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章,评审

    doi：10.3238/arztebl.2009.0175

    authors： Wagenlehner FM,Naber KG,Bschleipfer T,Brähler E,Weidner W

    更新日期：2009-03-01 00:00:00

  • Eosinophilia in returning travelers and migrants.

    abstract：:Levels of lead, cadmium, and mercury were examined in breast feathers of terns nesting on offshore islets near Culebra, Puerto Rico and on Michaelmas Cay and Heron Island on the Great Barrier Reef, Australia. Levels of all metals in these tropical terns were predicted to be lower than those of terns nesting in tempera...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章

    doi：10.3238/arztebl.2008.0801

    authors： Ehrhardt S,Burchard GD

    更新日期：2008-11-01 00:00:00

  • Postpartum cardiomyopathy: a cardiac emergency for gynecologists, general practitioners, internists, pulmonologists, and cardiologists.

    abstract：:The objective of this article was to investigate the safety and regenerative potential of a newly developed biomimetic scaffold when applied to osteochondral defects in an animal model. A new multilayer gradient nano-composite scaffold was obtained by nucleating collagen fibrils with hydroxyapatite nanoparticles. In t...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章

    doi：10.3238/arztebl.2008.0751

    authors： Hilfiker-Kleiner D,Schieffer E,Meyer GP,Podewski E,Drexler H

    更新日期：2008-10-01 00:00:00

  • Hereditary cancer syndromes.

    abstract：:The objective of this article was to investigate the safety and regenerative potential of a newly developed biomimetic scaffold when applied to osteochondral defects in an animal model. A new multilayer gradient nano-composite scaffold was obtained by nucleating collagen fibrils with hydroxyapatite nanoparticles. In t...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章

    doi：10.3238/arztebl.2008.0706

    authors： Rahner N,Steinke V

    更新日期：2008-10-01 00:00:00

  • The pathophysiology, diagnosis, and treatment of constipation.

    abstract：:The objective of this article was to investigate the safety and regenerative potential of a newly developed biomimetic scaffold when applied to osteochondral defects in an animal model. A new multilayer gradient nano-composite scaffold was obtained by nucleating collagen fibrils with hydroxyapatite nanoparticles. In t...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章,评审

    doi：10.3238/arztebl.2009.0424

    authors： Müller-Lissner S

    更新日期：2009-06-01 00:00:00

  • Perceived or true obesity: which causes more suffering in adolescents? Findings of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS).

    abstract：:A central issue in genome-wide association (GWA) studies is assessing statistical significance while adjusting for multiple hypothesis testing. An equally important question is the statistical efficiency of the GWA design as compared to the traditional sequential approach in which genome-wide linkage analysis is follo...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章

    doi：10.3238/arztebl.2008.0406

    authors： Kurth BM,Ellert U

    更新日期：2008-06-01 00:00:00

  • Urticaria: its history-based diagnosis and etiologically oriented treatment.

    abstract：:A central issue in genome-wide association (GWA) studies is assessing statistical significance while adjusting for multiple hypothesis testing. An equally important question is the statistical efficiency of the GWA design as compared to the traditional sequential approach in which genome-wide linkage analysis is follo...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章

    doi：10.3238/arztebl.2008.0458

    authors： Maurer M,Grabbe J

    更新日期：2008-06-01 00:00:00

  • Trend reversal in the frequency of mycoses in hematological neoplasias: autopsy results from 1976 to 2005.

    abstract：:A central issue in genome-wide association (GWA) studies is assessing statistical significance while adjusting for multiple hypothesis testing. An equally important question is the statistical efficiency of the GWA design as compared to the traditional sequential approach in which genome-wide linkage analysis is follo...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章

    doi：10.3238/arztebl.2008.0501

    authors： Donhuijsen K,Petersen P,Schmid WK

    更新日期：2008-07-01 00:00:00

  • Susceptible, intermediate, and resistant - the intensity of antibiotic action.

    abstract：:A central issue in genome-wide association (GWA) studies is assessing statistical significance while adjusting for multiple hypothesis testing. An equally important question is the statistical efficiency of the GWA design as compared to the traditional sequential approach in which genome-wide linkage analysis is follo...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章

    doi：10.3238/arztebl.2008.0657

    authors： Rodloff A,Bauer T,Ewig S,Kujath P,Müller E

    更新日期：2008-09-01 00:00:00

  • Mortality following myocardial infarction in women and men: an analysis of insurance claims data from inpatient hospitalizations.

    abstract：:Expression of the cell-surface protein CD47 allows some normal cells to avoid phagocytosis by macrophages. In this issue, Jaiswal et al. (2009) and Majeti et al. (2009) show that elevated CD47 expression by leukemic stem cells inhibits macrophage activity and is an indicator of poor prognosis for patients with acute m...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章

    doi：10.3238/arztebl.2008.0279

    authors： Heller G,Babitsch B,Günster C,Möckel M

    更新日期：2008-04-01 00:00:00

  • Guideline-compatible treatment of breast cancer patients: the status quo in schleswig-holstein.

    abstract：:Expression of the cell-surface protein CD47 allows some normal cells to avoid phagocytosis by macrophages. In this issue, Jaiswal et al. (2009) and Majeti et al. (2009) show that elevated CD47 expression by leukemic stem cells inhibits macrophage activity and is an indicator of poor prognosis for patients with acute m...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章

    doi：10.3238/arztebl.2008.0337

    authors： Waldmann A,Pritzkuleit R,Raspe H,Katalinic A

    更新日期：2008-05-01 00:00:00

  • Treatment of preterm infants at the lower margin of viability--a comparison of guidelines in German speaking countries.

    abstract：:The levels of blood glucose (BG) in humans tend to increase with age deviating from the norm specified for the young adults. Such elevation is often considered as a factor contributing to an increase in risks of disease and death. The proper use of intervention strategies coping with or preventing consequences of BG e...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章

    doi：10.3238/arztebl.2008.0047

    authors： Hentschel R,Reiter-Theil S

    更新日期：2008-01-01 00:00:00

  • The treatment of secondary hemochromatosis.

    abstract：:Health care reform is moving forward at a frantic pace. There have been 3 documents released from the Senate Finance Committee and proposed legislation from the Senate HELP Committee and the House of Representatives Tri-Committee on Health Reform. The push for legislative action has not been sidetracked by the economi...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章,评审

    doi：10.3238/arztebl.2009.0499

    authors： Gattermann N

    更新日期：2009-07-01 00:00:00

  • Dangerous errors in the diagnosis and treatment of bony tuberculosis.

    abstract：:Carotenoids, important lipid-soluble antioxidants in photosynthetic tissues, are known to be completely absent in rice endosperm. Many studies, involving transgenic manipulations of carotenoid biosynthesis genes, have been performed to get carotenoid-enriched rice grain. Study of genes involved in their biosynthesis c...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章

    doi：10.3238/arztebl.2009.0573

    authors： Herzog A

    更新日期：2009-09-01 00:00:00

  • Cataract surgery with implantation of an artificial lens.

    abstract：:Rapid attachment to actin of the detached motor domain of myosin dimers with one motor domain already attached has been hypothesized to explain the stretch-induced changes in X-ray interference and stiffness of active muscle. Here, using half-sarcomere mechanics in single frog muscle fibres (2.15 microm sarcomere leng...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章,评审

    doi：10.3238/arztebl.2009.0695

    authors： Kohnen T,Baumeister M,Kook D,Klaproth OK,Ohrloff C

    更新日期：2009-10-01 00:00:00

  • Placebo: misunderstandings and prejudices.

    abstract：BACKGROUND:Lead exposure has long been associated with deficits in IQ among children. However, few studies have assessed the impact of lead on specific domains of behavior and cognition. OBJECTIVE:We evaluated the associations between lead and different domains of neurobehavior and their relative sensitivity to lead. ...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章,评审

    doi：10.3238/arztebl.2009.0751

    authors： Breidert M,Hofbauer K

    更新日期：2009-11-01 00:00:00

  • Renal failure--measuring the glomerular filtration rate.

    abstract：OBJECTIVE:To identify predictors of negative symptomatic outcomes at 6 months after cholecystectomy, surgical removal of the gallbladder, which is the preferred treatment for gallstone disease. After cholecystectomy, a substantial number of patients report persistence of symptoms. METHODS:In this prospective follow-up...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章,评审

    doi：10.3238/arztebl.2009.0849

    authors： Thomas C,Thomas L

    更新日期：2009-12-01 00:00:00

  • Periocular plastic surgery.

    abstract：:Data from three Swedish health care registries--the Medical Birth Registry, the Registry of Congenital Malformations, and the Hospital Discharge Registry--were linked for the 9-year period 1973-1981 to identify women who had appendectomy during pregnancy and their offspring, and to determine several pregnancy outcomes...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章,评审

    doi：10.3238/arztebl.2010.0141

    authors： Hintschich C

    更新日期：2010-03-01 00:00:00

  • Chlamydial zoonoses.

    abstract：:Abiotic stresses such as cold, water deficit, and salt stresses severely reduce crop productivity. Tomato (Solanum lycopersicum) is an important economic crop; however, not much is known about its stress responses. To gain insight into stress-responsive gene regulation in tomato plants, we identified transcription fac...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章,评审

    doi：10.3238/arztebl.2010.0174

    authors： Rohde G,Straube E,Essig A,Reinhold P,Sachse K

    更新日期：2010-03-01 00:00:00

  • The financing of drug trials by pharmaceutical companies and its consequences. Part 1: a qualitative, systematic review of the literature on possible influences on the findings, protocols, and quality of drug trials.

    abstract：:Exposure of young mothers and newborns to organochlorine pesticides (OCPs) were assessed by measuring the levels of OCPs in human milk (HM) and maternal blood (MB) and umbilical cord blood (UCB) samples from Guangzou in China. 21 OCPs were analyzed using gas chromatography/mass spectrometry (GC/MS). The results showed...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章

    doi：10.3238/arztebl.2010.0279

    authors： Schott G,Pachl H,Limbach U,Gundert-Remy U,Ludwig WD,Lieb K

    更新日期：2010-04-01 00:00:00

  • The uses and limitations of whole-body magnetic resonance imaging.

    abstract：:From January 1979 to December 1987, 99 patients with a diagnosis of localized soft-tissue sarcoma of the extremities received preoperative radiation therapy (50 patients) or postoperative irradiation (49 cases). In the preoperative RT group, doses ranged from 42 Gy/14 fractions to 51 Gy/17 fractions; the patients trea...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章,评审

    doi：10.3238/arztebl.2010.0383

    authors： Schmidt G,Dinter D,Reiser MF,Schoenberg SO

    更新日期：2010-06-01 00:00:00

  • Vision screening in preschool children: do the data support universal screening?

    abstract：:In-hospital care of seriously ill children has improved dramatically with advances in emergency medicine and pediatric intensive care. Interhospital transport is necessary for a large percentage of critically ill or injured children. The appropriateness of care received during the transport phase is a crucial componen...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章,评审

    doi：10.3238/arztebl.2010.0495

    authors： Lagrèze WA

    更新日期：2010-07-01 00:00:00

  • Sample size calculation in clinical trials: part 13 of a series on evaluation of scientific publications.

    abstract：BACKGROUND:Ischemia-reperfusion injury (IRI) is responsible for primary liver dysfunction and failure after transplantation. The mitochondrial pathway appears to be involved in liver ischemia-reperfusion injury. Mitochondrial ATP-sensitive K (mitoK(ATP)) channels play a central role in protecting the heart from injury ...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章,评审

    doi：10.3238/arztebl.2010.0552

    authors： Röhrig B,du Prel JB,Wachtlin D,Kwiecien R,Blettner M

    更新日期：2010-08-01 00:00:00

  • Shift work and cancer: the evidence and the challenge.

    abstract：:Mechanical gastric polyp complications are very rare occurrences most commonly related to hyperplastic polyps. We report here the case of a young woman with a 12-cm adenomatous polyp on the great curvature of the stomach diagnosed incidentally during tests for anaemia. Later, the patient was referred to hospital for r...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章,评审

    doi：10.3238/arztebl.2010.0657

    authors： Erren TC,Falaturi P,Morfeld P,Knauth P,Reiter RJ,Piekarski C

    更新日期：2010-09-01 00:00:00

  • The prevention, diagnosis, and treatment of dyslexia.

    abstract：BACKGROUND:Reading and spelling disorder (dyslexia) is one of the more common specific developmental disorders, with a prevalence of approximately 5%. It is characterized by severe impairment of learning to read and spell. METHODS:We discuss major aspects of the diagnosis, treatment, and prevention of dyslexia on the ...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章,评审

    doi：10.3238/arztebl.2010.0718

    authors： Schulte-Körne G

    更新日期：2010-10-01 00:00:00

  • Gliomas in adults.

    abstract：:As reflected in the amount of controversy, few areas in psychology have undergone such dramatic conceptual changes in the past decade as the emerging science of heuristics. Heuristics are efficient cognitive processes, conscious or unconscious, that ignore part of the information. Because using heuristics saves effort...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章,评审

    doi：10.3238/arztebl.2010.0799

    authors： Schneider T,Mawrin C,Scherlach C,Skalej M,Firsching R

    更新日期：2010-11-01 00:00:00

  • The prenatal diagnosis of genetic diseases.

    abstract：PURPOSE:To explore the regional patterns of white matter (WM) tract damage in (a) patients with probable Alzheimer disease (AD) and (b) patients with amnestic mild cognitive impairment (aMCI) and at least one abnormal biomarker and to investigate whether WM damage is related to gray matter (GM) atrophy. MATERIALS AND ...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章,评审

    doi：10.3238/arztebl.2010.0857

    authors： Wieacker P,Steinhard J

    更新日期：2010-12-01 00:00:00

  • Awareness under general anesthesia.

    abstract：:The effects of some general purpose drugs on the deactivation and activity measurement of the chicken pineal gland enzyme serotonin N-acetyl transferase (EC 2.3.1.5.) were studied. The drugs used were EGTA and two neutral surfactants, Nonidet P40 and Triton X-100. Enzyme activity showed significant variations ranging ...

    journal_title：Deutsches Arzteblatt international

    pub_type： 杂志文章,评审

    doi：10.3238/arztebl.2011.0001

    authors： Bischoff P,Rundshagen I

    更新日期：2011-01-01 00:00:00