Abstract:
:Brucellosis is a zoonosis that has a devastating impact on the economy and public health, particularly in the Middle East, including Egypt. This study aimed to define risk factors associated with brucellosis in humans and in their cattle in Fayoum governorate - Upper Egypt. Also, molecular genotyping of recovered Brucella isolates from human cases and their cattle to assess the potential cross-species transmission in the study region. Data were obtained via double matched case-control studies for brucellosis in humans (106 cases and 160 controls) and in their cattle (78 cattle cases and 105 cattle controls). The results of multivariate regression analysis revealed that predictors of human brucellosis were animal-related occupations (OR 2.1, P 0.02), previous infection in other household members (OR 3.2, P 0.007), eating home-made soft cheese (OR 2.3, P 0.03), and exposure to cattle abortions (OR 6.9, P < 0.001). For cattle, predictors of brucellosis were maturity ≥2 years of age (OR 2.9, P 0.01), ≥2 animals reared by the same household (OR 3.7-6.9, P ≤ 0.001), and recent abortion (OR 15.2, P 0.01). Twelve Brucella isolates were recovered from eight human cases (7.5%, 8/106) and four cattle cases (6.2%, 4/65). All isolates were B. melitensis biovar 3. Analysis of the IS711 gene sequence revealed complete homology (100%) between isolates. Six virulence genes were utilized for virutyping: virB (100%), omp25 (100%), amiC (100%), ure (91.7%), wbkA (91.7%), and bvfA (75%). Virutyping revealed four virutypes: V1 (lack bvfA, 16.7%), V2 (harbored all genes, 66.7%), V3 (lack wbkA, 8.3%), and V4 (lack wbkA and ure, 8.3%). Repetitive extragenic palindromic PCR (REP-PCR) typing revealed two REP types. Combined REP-PCR/virulence genotyping revealed five different genotypes (G1-G5) for the detected isolates and a unique genotype for the reference strain (G6, B. melitensis bv3 Ether). Human and cattle isolates from the same household had matched genotypes. In conclusion, there were widespread risk factors among the cases studied. Health education for high-risk groups is essential for disease prevention, and combined REP-PCR/virulence genotyping is a quick tool for traceability, particularly in developing countries endemic with brucellosis as Egypt.
journal_name
One Healthjournal_title
One health (Amsterdam, Netherlands)authors
Abdel-Hamid NH,Ghobashy HM,Beleta EI,Elbauomy EM,Ismail RI,Nagati SF,Hassan SK,Elmonir Wdoi
10.1016/j.onehlt.2021.100281keywords:
["Brucella","Cattle","Egypt","Human","Molecular typing","Risk factors"]subject
Has Abstractpub_date
2021-06-19 00:00:00pages
100281issn
2352-7714pii
S2352-7714(21)00071-9journal_volume
13pub_type
杂志文章相关文献
文献大全abstract::A number of viruses transmitted by mosquitoes are well known to cause disease in both humans and horses, ranging from mild fevers to mortal neurological disease. A recently discovered connection between the alphavirus Sindbis virus (SINV) and neurological disease in horses in South Africa initiated this serological st...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章
doi:10.1016/j.onehlt.2021.100242
更新日期:2021-03-25 00:00:00
abstract::COVID-19 has emerged as the world's biggest challenge that has not only threatened human lives but also had an immense impact on the economy, safety and religious practices. The situation has worsened due to the lack of proper guidelines for fighting the sudden unexpected outbreaks. The world was not prepared for this...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章,评审
doi:10.1016/j.onehlt.2021.100229
更新日期:2021-06-01 00:00:00
abstract::Pathogens associated with haemorrhagic fever commonly have zoonotic origins. The first documented imported case of likely viral severe haemorrhagic fever in Sweden occurred in 1990. Despite extensive study, no aetiological agent was identified. Following retrospective investigation with total RNA-sequencing of samples...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章
doi:10.1016/j.onehlt.2021.100217
更新日期:2021-01-22 00:00:00
abstract::Enterocytozoon bieneusi, a fungus-like protist parasite, causes symptomatic and asymptomatic intestinal infections in terrestrial animals and is also abundant in the environment. This parasite has been isolated from a variety of host types including humans, livestock, companion animals, birds, and wildlife, as well as...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章,评审
doi:10.1016/j.onehlt.2020.100209
更新日期:2020-12-24 00:00:00
abstract::Wild animals represent a constant source of Trichinella spp. infections for domestic animals and humans. To date, four species of Trichinella have been isolated in wild boar populations in Europe: T. pseudospiralis, T. spiralis, T. britovi and T. nativa, in addition to several mixed infection types and one hybrid form...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章
doi:10.1016/j.onehlt.2020.100172
更新日期:2020-09-29 00:00:00
abstract::Tuberculosis (TB) in humans is primarily caused by Mycobacterium tuberculosis (M. tuberculosis), with millions of infections and hundreds of thousands of deaths worldwide. It creates a substantial economic burden on the community. Unlike M. tuberculosis, Mycobacterium bovis infects cattle and causes bovine TB, also kn...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章
doi:10.1016/j.onehlt.2020.100156
更新日期:2020-08-11 00:00:00
abstract::Cocoa production is the major contributor to livelihoods for farming families that constitute nearly two-thirds of the population of the Autonomous Region of Bougainville, a Province in Papua New Guinea (PNG). These families, living mostly in subsistence poverty as a result of the Bougainville Civil War (1988-98), hav...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章
doi:10.1016/j.onehlt.2020.100143
更新日期:2020-05-15 00:00:00
abstract::Controlling antibiotic resistance is a global concern. The One Health initiative has provided a strategy to deal with this problem efficiently within a country. However, due to the global nature of the problem it is paramount not only to focus on specific countries, but to establish ways to avoid the development of an...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章
doi:10.1016/j.onehlt.2019.100100
更新日期:2019-08-14 00:00:00
abstract::Significant global ecological changes continue to drive emergence of tick-borne zoonoses around the world. This poses an important threat to both human and animal health, and highlights the need for surveillance systems that are capable of monitoring these complex diseases effectively across different stages of the em...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章,评审
doi:10.1016/j.onehlt.2019.100083
更新日期:2019-02-11 00:00:00
abstract::As a result of the close relationships between Arctic residents and the environment, climate change has a disproportionate impact on Arctic communities. Despite the need for One Health responses to climate change, environmental monitoring is difficult to conduct in Arctic regions. The Local Environmental Observer (LEO...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章
doi:10.1016/j.onehlt.2018.10.002
更新日期:2018-10-11 00:00:00
abstract::In 2016 and 2017 the first three MOOCs (Massive Online Open Course) addressing One Health were released, two of them by University of Geneva and University of Basel (Switzerland). With the support of Swiss School of Public Health and using these two highly interdisciplinary MOOCs, the first 'Global Flipped Classroom i...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章
doi:10.1016/j.onehlt.2018.02.001
更新日期:2018-02-12 00:00:00
abstract::Bats are unique mammals that are reservoirs of high levels of virus diversity. Although several of these viruses are zoonotic, the majority are not. Astroviruses, transmitted fecal-orally, are commonly detected in a wide diversity of bat species, are prevalent at high rates and are not thought to directly infect human...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章
doi:10.1016/j.onehlt.2017.10.001
更新日期:2017-10-06 00:00:00
abstract::The need for multidisciplinary research to address today's complex health and environmental challenges has never been greater. The One Health (OH) approach to research ensures that human, animal, and environmental health questions are evaluated in an integrated and holistic manner to provide a more comprehensive under...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章,评审
doi:10.1016/j.onehlt.2017.03.004
更新日期:2017-03-24 00:00:00
abstract::One Health is held as an approach to solve health problems in this era of complexity and globalization, but inadequate attention has been paid to the competencies required to build successful teams and programs. Most of the discussion on developing One Health teams focuses on creating cross-disciplinary awareness and ...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 社论
doi:10.1016/j.onehlt.2016.10.002
更新日期:2016-10-28 00:00:00
abstract::There is an increasing interest in determining the impact of vaccine technologies developed using public funding targeted at international development, and understanding the factors and ingredients which contribute to the success and impacts of such vaccines. This paper chronicles the development of a live vaccine aga...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章
doi:10.1016/j.onehlt.2016.07.002
更新日期:2016-07-22 00:00:00
abstract::The "Asian tiger mosquito", Aedes albopictus, is highly invasive, an aggressive biter and a major arbovirus vector. It is not currently present on mainland Australia despite being intercepted on numerous occasions at international ports and infesting the Torres Strait of Australia since at least 2004. In the current p...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章,评审
doi:10.1016/j.onehlt.2016.02.001
更新日期:2016-02-24 00:00:00
abstract:BACKGROUND:Organochlorine contaminants (OCs), like polychlorinated biphenyls (PCBs) and dichlorodiphenyltrichloroethanes (DDTs), are widespread marine pollutants resulting from massive historical use and environmental persistence. Exposure to and health effects of these OCs in the marine environment may be examined by ...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章
doi:10.1016/j.onehlt.2015.08.003
更新日期:2015-09-14 00:00:00
abstract::Concentrated animal feeding operations (CAFOs) present highly efficient means of meeting food demands. CAFOs create unique conditions that can affect the health and environment of animals and humans within and outside operations, leading to potential epidemiological concerns that scale with operational size. One such ...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章,评审
doi:10.1016/j.onehlt.2021.100246
更新日期:2021-04-08 00:00:00
abstract::Hepatitis E virus (HEV) infection is an emerging infection that is of major public health concern, especially in some vulnerable groups like immunosuppressed individuals, pregnant women and HBV-coinfected individuals. HEV is transmitted faecal/oral or zoonotically depending on the HEV-genotype. This study aimed at inv...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章
doi:10.1016/j.onehlt.2021.100256
更新日期:2021-04-28 00:00:00
abstract:Background:During the first wave of COVID-19 it was hypothesized that COVID-19 is subject to multi-wave seasonality, similar to Influenza-Like Illnesses since time immemorial. One year into the pandemic, we aimed to test the seasonality hypothesis for COVID-19. Methods:We calculated the average annual time-series for ...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章
doi:10.1016/j.onehlt.2021.100277
更新日期:2021-12-01 00:00:00
abstract::Antimicrobial resistance (AMR) has been recognized as one of the greatest global threats for human and animal health. The present review retrieved up to date information on the epidemiology of AMR in the animal-source food chain in Ethiopia focusing on AMR in bacterial species isolated from food handlers, live animals...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章,评审
doi:10.1016/j.onehlt.2021.100286
更新日期:2021-06-29 00:00:00
abstract::Crimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne viral zoonotic disease caused by Crimean-Congo hemorrhagic fever virus (CCHFV). The disease is usually asymptomatic in domestic and wild animals, both of which may act as reservoirs of the virus. CCHF is endemic in parts of Africa, Asia, the Middle East and...
journal_title:One health (Amsterdam, Netherlands)
pub_type: 杂志文章
doi:10.1016/j.onehlt.2021.100290
更新日期:2021-07-07 00:00:00