Abstract：
:Pathogens associated with haemorrhagic fever commonly have zoonotic origins. The first documented imported case of likely viral severe haemorrhagic fever in Sweden occurred in 1990. Despite extensive study, no aetiological agent was identified. Following retrospective investigation with total RNA-sequencing of samples collected between 7 and 36 days from onset of symptoms we identified dengue virus 3 (DENV-3) and a human pegivirus (HPgV). We conclude that the patient likely suffered from haemorrhagic symptoms due to an atypical severe and undiagnosed dengue infection.
journal_name
One Healthjournal_title
One health (Amsterdam, Netherlands)authors
Alfsnes K,Lagerqvist N,Vene S,Bohlin J,Verner-Carlsson J,Ekqvist D,Bråve A,Holmes EC,Shi W,Pettersson JHdoi
10.1016/j.onehlt.2021.100217keywords:
["Dengue haemorrhagic fever","Dengue virus","Human pegivirus","Meta-transcriptomics","RNA-sequencing","Viral haemorrhagic fever"]subject
Has Abstractpub_date
2021-01-22 00:00:00pages
100217issn
2352-7714pii
S2352-7714(21)00007-0journal_volume
12pub_type
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