Leiomyosarcomatous transformation of unknown pediatric primary brainstem lesion following radiotherapy. Case report.

Abstract:

:Primary leiomyosarcoma of the central nervous system is rare and has been described both de novo and following temporally remote radiotherapy for a different unrelated malignancy. The authors report the case of a 42-year-old man in whom 60Co radiation treatment had been performed for an unknown primary mass in the brainstem 25 years previously. He presented with progressive neurological deterioration after undergoing many years of conservative therapy. A stereotactic biopsy sampling procedure was performed, and examination of the left cerebral pedunculopontine lesion revealed a spindle cell neoplasm. Histopathological and immunohistochemical examination of the tumor obtained from definitive resection suggested leiomyosarcomatous transformation of ganglioglioma.

journal_name

Neurosurg Focus

journal_title

Neurosurgical focus

authors

Yeh DJ,Hessler RB,Lee MR

doi

10.3171/foc.2002.12.6.13

subject

Has Abstract

pub_date

2002-06-15 00:00:00

pages

ecp2

issue

6

issn

1092-0684

pii

1206cp2

journal_volume

12

pub_type

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