Abstract:
:Median cleft lip is a midline vertical cleft through the upper lip in the absence of a prolabial remnant. This may occur as a sporadic event or be part of an inherited sequence of anomalies. A failure of formation or fusion of the medial nasal prominences derived from the frontonasal prominence is ultimately responsible for this aberration. Two categories of dysplasia are associated: (1) frontonasal deformity associated with hypotelorism and (2) median facial cleft syndrome associated with hypertelorism. A patient presents with median cleft lip, mild bifid nose, and hypertelorism. Following surgical reconstruction, a good result is achieved. The embryology, implications for associated abnormalities, and surgical technique for treating these cases are discussed.
journal_name
Cleft Palate Craniofac Jjournal_title
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Associationauthors
Apesos J,Anigian GMdoi
10.1597/1545-1569_1993_030_0094_mcotli_2.3.co_2subject
Has Abstractpub_date
1993-01-01 00:00:00pages
94-6issue
1eissn
1055-6656issn
1545-1569journal_volume
30pub_type
杂志文章abstract:OBJECTIVE:Since its first description, the A strain of mice have been utilized extensively as models to study the processes involved in clefting of the midfacial region. Of the A substrains, the A/WySn has a spontaneous rate of clefting of the lip of about 20% to 30%. The A/WySn mouse model was utilized in this study t...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/1545-1569_2001_038_0486_pamaoa_2.0.co_2
更新日期:2001-09-01 00:00:00
abstract:OBJECTIVE:To present a child born with both mitochondrial myopathy and cleft palate, outlining medical complications of this dual diagnosis-the first reported case in English literature. METHODS:A preterm Caucasian boy presented to the cleft palate clinic at birth for evaluation of a secondary cleft palate. Multiple a...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/03-040.1
更新日期:2005-05-01 00:00:00
abstract::To understand the etiology of maxillary hypoplasia better, which is common in individuals with cleft palate and other craniofacial anomalies, the relative growth and contribution of the maxillary and palatine segments to enlargement of the hard palate was examined in rhesus monkeys. The purpose of the study was to ide...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/1545-1569_1993_030_0302_dgacot_2.3.co_2
更新日期:1993-05-01 00:00:00
abstract:OBJECTIVE:We aimed to characterize the fibroblast phenotype of patients by analyzing gene and protein expression of cleft lip and/or cleft palate fibroblasts in relation to collagen turnover and extracellular matrix remodeling. PATIENTS:Human palatal fibroblasts were obtained from three healthy subjects without cleft ...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/07-196.1
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:Routine hospital admission following pharyngeal flap (PF) to correct velopharyngeal insufficiency (VPI) is the standard at most hospitals. Nevertheless, there is increasing resistance from third-party providers to approve stays longer than a "short stay" (23-hour) observation period. The purpose of the curren...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1177/1055665617732776
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVES:To propose a new scale for evaluating the position of the bone graft within the cleft and assess its inter- and intraobserver reliability. DESIGN:Sixty-six patients (70 cleft sites) over a 14-year period were assessed, 90% of patients retrospectively and 10% prospectively. The radiographs were reviewed by t...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/1545-1569_2002_039_0255_anstar_2.0.co_2
更新日期:2002-05-01 00:00:00
abstract:OBJECTIVE:The current review and survey aim to assess the effectiveness of acellular dermal matrix (ADM) in the repair of cleft palate and oronasal fistula and to evaluate the current trends of ADM use in palate surgery. DESIGN:A systematic review of English articles was conducted using MEDLINE (1960 to July 1, 2016),...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1177/1055665618774028
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:To investigate the stresses and strains of an endosseous dental implant in patients with different types of cleft palate in a finite element model. MATERIALS AND METHODS:Seven three-dimensional (3D) maxillary models were designed on a personal computer according to computed tomography slice data obtained fro...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/04-091r1.1
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:In this report, the orthodontic treatment combined with rigid external distraction osteogenesis in a 5.5-year-old girl with midfacial hypoplasia and oligodontia is described. PATIENT:The child presented with a reduced maxilla, protruding lower lip, skeletal Class III jaw relationship with a low mandibular pl...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/1545-1569_2003_040_0207_redofa_2.0.co_2
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVE:The aim of this work was to investigate in more detail the dental clinical features that could serve to define subphenotypes of oral clefts. DESIGN:Dental records of oral cleft subjects from a group of 164 cases were examined, and 157 were included in this study. In addition, 65 families with two or more sib...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/09-159
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:The goal of the consolidation phase of mandible distraction is to maintain the improvement in maxillomandibular form and relationship while the generated tissue ossifies. During this period, external deforming forces can act on the healing generated bone. The purpose of this study was to describe the potentia...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/1545-1569_2003_040_0233_caotcp_2.0.co_2
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:With the recent advances of surgical adjuncts including presurgical naso-alveolar molding and postoperative nasal stenting, information on the anthropometric evaluation of cleft lip nasal symmetry after primary rhinoplasty is lacking. METHOD:Twenty-nine nonsyndromic patients with complete unilateral cleft l...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/15-125
更新日期:2016-09-01 00:00:00
abstract::Children with Prader-Willi Syndrome (PWS) may present with a malocclusion and have a high propensity of developing obstructive sleep apnea (OSA). Obstructive sleep apnea is associated with short- and long-term adverse effects that negatively impact children with PWS. A case of a 15-year-old male with PWS, OSA, and a d...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1177/1055665618775724
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:We present an audit of primary cleft palate surgery at our unit, including rates of oronasal fistula development, speech outcomes, and rates of velopharyngeal insufficiency requiring secondary surgery. DESIGN:A retrospective study of patients with all cleft palate types, born between January 1990 and Decembe...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/06-205.1
更新日期:2008-03-01 00:00:00
abstract::Intramuscular hydroxyzine was used alone for sedation in 18 cleft lip repairs with patients under 6 weeks of age. After injection of local anesthesia, the infants were quiet throughout the procedure. Blood pressure, pulse, respiration, and temperatures were normal throughout and the oxygen saturation remained above 94...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/1545-1569_1992_029_0481_clruih_2.3.co_2
更新日期:1992-09-01 00:00:00
abstract:OBJECTIVES:Reviews of the quality of reporting of randomized controlled trials (RCTs) have recently been conducted in different surgical specialties. In this review of RCTs relating to cleft lip, cleft palate, and cleft lip and palate (CL/P), we investigate the quality of reporting against the Consolidated Standards of...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章,评审
doi:10.1597/14-267
更新日期:2017-03-01 00:00:00
abstract::Hay-Wells/ankyloblepharon-ectodermal dysplasia-clefting syndrome is a rare autosomal dominant disorder characterized by ankyloblepharon, ectodermal dysplasia, and cleft lip and/or cleft palate. Mutations in the p63 gene recently have been shown to be etiologic in the majority of cases of ankyloblepharon-ectodermal dys...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章,评审
doi:10.1597/06-065
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVE:To explore the application of magnetic resonance imaging (MRI) in the evaluation of patients with cleft palate before and after primary palatoplasty with particular attention focused on the levator veli palatini muscle. DESIGN:Prospective study using MRIs of subjects before and after primary cleft palate sur...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 临床试验,杂志文章
doi:10.1597/03-060.1
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:To determine the epidemiology of cleft lip and/or palate (CL/P) in births in hospitals of Hamedan City, Iran, and to evaluate the etiologic factors that have a role in the development of these anomalies. DESIGN:This research was a 15-year cross-sectional study (1993 to 2008). PARTICIPANTS:All infants born w...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/09-035
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:The purposes of this electromyographic study were to examine whether levator veli palatini muscle activity during speech can be changed with placement of a speech appliance and to clarify whether or not the change is related to the type of speech appliance used. DESIGN:Electromyography (EMG) was performed du...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/1545-1569_2000_037_0478_eopoas_2.0.co_2
更新日期:2000-09-01 00:00:00
abstract::Two cases are presented that show increased loudness as contributory to the occurrence of audible posterior nasal turbulence as an obligatory symptom. Case 1 was an 18-month-old boy with repaired cleft palate who exhibited sporadic posterior nasal turbulence with velar flutter that was associated with increased loudne...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1177/1055665617730366
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:To determine whether early routine grommet insertion in children with cleft palate has a beneficial effect on hearing and speech and language development compared with conservative management. DESIGN:Systematic review of randomized controlled trials, controlled clinical trials, case series, and prospective a...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章,评审
doi:10.1597/07-219.1
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:To analyze congenital lateral maxillary growth for patients with bilateral cleft lip and palate (BCLP). DESIGN:A retrospective study. SETTING:Kanagawa Children's Medical Center. MATERIALS:Images from computed tomography (CT) of patients with BCLP and control patients that were previously used for treatment...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1177/1055665619874979
更新日期:2020-03-01 00:00:00
abstract::A national survey was conducted concerning methods used for the evaluation of velopharyngeal function with emphasis on the role of nasendoscopy. Forty-five percent of questionnaires were returned. Ninety percent of the responding teams indicated that nasendoscopy was available. Sixty-one percent agreed that endoscopy ...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/1545-1569_1993_030_0035_roasoc_2.3.co_2
更新日期:1993-01-01 00:00:00
abstract::Craniopagus twins are a rare phenomenon and present numerous challenges in separation. Due to the paucity of data, it is paramount to evaluate outcomes based on case studies to continue improving medical and surgical management of these patients. We present a case report of craniopagus twins cared for by the senior au...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1177/1055665618811534
更新日期:2019-07-01 00:00:00
abstract::The etiology of most cases of isolated cleft palate (CP) is unknown. The relative importance of genes and environment can be studied using the classical twin method but only few and potentially highly selected CP twin data are available. The present CP twin study was based on four Danish nationwide ascertainment sourc...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/1545-1569_1993_030_0469_icpidm_2.3.co_2
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:Parry-Romberg syndrome (PRS) is a rare craniofacial disease that causes progressive hemifacial atrophy of the soft tissue before spontaneously entering remission. Autologous fat grafting may provide a less invasive alternative, producing aesthetically pleasing results while avoiding the need for traditional ...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章,评审
doi:10.1597/14-232
更新日期:2016-05-01 00:00:00
abstract::Experimental rabbit models of postnatal coronal suture (CS) synostosis have helped make significant contributions towards the understanding and surgical management of human congenital craniosynostosis. The present study compares craniofacial growth patterns in animals with experimental CS immobilization and in a rabbi...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/1545-1569_1993_030_0121_cbcssi_2.3.co_2
更新日期:1993-03-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to assess the volume, area, and dimensions of the oropharyngeal airway (OPA) in a previously repaired nonsyndromic unilateral cleft lip and palate (UCLP) versus bilateral cleft lip and palate (BCLP) patients when compared with noncleft controls using cone beam computed tomograp...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/15-322
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:To identify the long-term effects of palate repair on craniofacial growth in patients with unilateral cleft lip and palate (UCLP). DESIGN:Retrospective cross-sectional study. SETTING:Sri Lankan Cleft Lip and Palate Project. SUBJECTS:Forty-eight adults with nonsyndromic unilateral cleft lip and palate, 29 m...
journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type: 杂志文章
doi:10.1597/04-077r.1
更新日期:2005-11-01 00:00:00