Abstract:
BACKGROUND:Plasma cell granuloma (PCG) is a rare non-neoplastic entity, with the precise etiology remaining unclear. Vertebra-affected spinal PCG has not been reported yet. This report presented a case with cross-segment spinal PCG in thoracolumbar region. CASE PRESENTATION:A 32-year-old male patient presented to the authors' hospital since his health check-up results showed osteolytic lesions in the thoracolumbar spine. He felt asymptomatic throughout the course. Radiological examination revealed destructive changes at T12 and L1 vertebrae. Whereas laboratory examination excluded malignant tumor. The results of routine incisional biopsy remained inconclusive, thereby necessitating complete excision of the lesions. Finally, the infiltration of plasma cells observed by pathological examination of the surgical specimen confirmed the diagnosis of PCG. CONCLUSIONS:To the authors' knowledge, this was the first case of cross-segment spinal PCG with osteolytic property. The possibility of PCG should be considered for the diagnosis and differential diagnosis of an osteolytic lesion in the spine. Since the etiology of PCG is unknown, the disorder was confirmed based on excluded diagnosis. Surgical resection is recommended both for the definite diagnosis and treatment of spinal PCG.
journal_name
BMC Musculoskelet Disordjournal_title
BMC musculoskeletal disordersauthors
Lin R,Wang S,Lin J,Zhang Z,Chen Xdoi
10.1186/s12891-020-03759-4subject
Has Abstractpub_date
2020-11-12 00:00:00pages
746issue
1issn
1471-2474pii
10.1186/s12891-020-03759-4journal_volume
21pub_type
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pub_type: 杂志文章,多中心研究,随机对照试验
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pub_type: 杂志文章
doi:10.1186/s12891-015-0724-x
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更新日期:2016-12-29 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章,多中心研究,随机对照试验
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