Abstract:
BACKGROUND:A lifesaving treatment for myocardial infarction is the placement of a stent in a closed or obstructed coronary artery. The largest modifiable risk factor after receiving a stent is medication adherence to Dual AntiPlatelet Therapy, a combination of P2Y12 inhibitors and aspirin. OBJECTIVE:This study aimed to determine the acceptability of a protocol and an intervention using the My Interventional Drug-Eluting Stent Educational App (MyIDEA) and to evaluate medication adherence using the proportion of days covered (PDC) and platelet activation tests in a multisite randomized controlled trial. METHODS:Potential participants who received a post percutaneous coronary intervention (PCI) procedure with a drug-eluting stent were approached. All patients older than 50 years and who spoke English were recruited. Participants were recruited, baseline demographics were collected, and the Hospital Anxiety and Depression Scale (HADS), Rapid Estimate of Adult Literacy in Medicine-Short Form, Burden-Benefit questionnaire, 36-Item Short Form Health Survey, and PCI knowledge questionnaire were administered. Block randomization was used to randomize participants to either usual care or MyIDEA supplementation. MyIDEA is a personalized educational intervention based on the Kolb experiential learning theory using patient narratives for education. During the visits, participants' blood was collected to measure platelet suppression from medication. During the second and third encounters, the Morisky medication adherence score and cardiology outcomes were measured. The study was conducted at the University of Illinois Hospital and John H Stroger Jr Cook County Hospital with appropriate ethical approvals. Platelet suppression was measured through aspirin reactive units and P2Y12 reactive units. Medication adherence was measured using the PDC. The analysis team was blinded to the participants' group membership. The primary outcome was a feasibility analysis of recruitment and retention. RESULTS:The mean age of participants was 60.4 years (SD 7.1); the majority of patients were black and non-Hispanic. The majority of patients' reading levels were seventh grade or above, and they were not very familiar with other electronic devices for information and communication. The number of control subjects was 21, and the number of participants in the interventional arm was 24. The interventional group was able to use MyIDEA in both the hospital and outpatient setting. However, there was no significant difference in platelet suppression or medication adherence between groups. There were also differences between the groups in terms of depression and anxiety, initially, as measured by HADS. No documented adverse event associated with the intervention was found. CONCLUSIONS:Elderly patients are willing to use tablet devices to be educated about health conditions. Additional studies are required to measure the effectiveness and determine the most suitable timing and location for patient education. TRIAL REGISTRATION:ClinicalTrials.gov NCT04439864; https://clinicaltrials.gov/ct2/show/NCT04439864.
journal_name
JMIR Mhealth Uhealthjournal_title
JMIR mHealth and uHealthauthors
Boyd AD,Ndukwe CI,Dileep A,Everin OF,Yao Y,Welland B,Field J,Baumann M,Flores JD Jr,Shroff A,Groo V,Dickens C,Doukky R,Francis R,Peacock G,Wilkie DJdoi
10.2196/15900subject
Has Abstractpub_date
2020-06-24 00:00:00pages
e15900issue
6issn
2291-5222pii
v8i6e15900journal_volume
8pub_type
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journal_title:JMIR mHealth and uHealth
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journal_title:JMIR mHealth and uHealth
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journal_title:JMIR mHealth and uHealth
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journal_title:JMIR mHealth and uHealth
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journal_title:JMIR mHealth and uHealth
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journal_title:JMIR mHealth and uHealth
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journal_title:JMIR mHealth and uHealth
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