Perturbation-based gait training to improve daily life gait stability in older adults at risk of falling: protocol for the REACT randomized controlled trial.

Abstract:

BACKGROUND:The European population is rapidly ageing. There is an urgent need for innovative solutions to reduce fall risk in older adults. Perturbation-based gait training is a promising new method to improve reactive balance responses. Whereas positive effects on task-specific dynamic balance recovery during gait have been shown in clinical or laboratory settings, translation of these effects to daily life gait function and fall risk is limited. We aim to evaluate the effect of a 4-week perturbation-based treadmill training on daily-life dynamic gait stability, assessed with inertial sensor data. Secondary outcomes are balance recovery performance, clinical balance and gait assessment scores, the amount of physical activity in daily life and falls incidence during 6 months follow-up. METHODS:The study is a monocenter assessor-blinded randomized controlled trial. The target study sample consists of 70 older adults of 65 years and older, living in the community and with an elevated risk of falling. A block-randomization to avoid seasonal effects will be used to allocate the participants into two groups. The experimental group receives a 4-week, two times per week perturbation-based gait training programme on a treadmill, with simulated slips and trips, in combination with cognitive dual tasks. The control group receives a 4-week, two times per week treadmill training programme under cognitive dual-task conditions without perturbations. Participants will be assessed at baseline and after the 4-weeks intervention period on their daily-life gait stability by wearing an inertial sensor on the lower back for seven consecutive days. In addition, clinical balance and gait assessments as well as questionnaires on falls- and gait-efficacy will be taken. Daily life falls will be followed up over 6 months by a fall calendar. DISCUSSION:Whereas perturbation-based training has shown positive effects in improving balance recovery strategies and in reducing laboratory falls, this study will contribute to investigate the translation of perturbation-based treadmill training effects in a clinical setting towards improving daily life gait stability and reducing fall risk and falls. TRIAL REGISTRATION:NTR7703 / NL66322.028.18, Registered: January 8, 2019; Enrolment of the first participant April 8, 2019.

journal_name

BMC Geriatr

journal_title

BMC geriatrics

authors

Rieger MM,Papegaaij S,Steenbrink F,van Dieën JH,Pijnappels M

doi

10.1186/s12877-020-01566-z

subject

Has Abstract

pub_date

2020-05-07 00:00:00

pages

167

issue

1

issn

1471-2318

pii

10.1186/s12877-020-01566-z

journal_volume

20

pub_type

杂志文章,随机对照试验
  • Advance directives and power of attorney for health care in the oldest-old - results of the AgeQualiDe study.

    abstract:BACKGROUND:Completion of advance directives (ADs) and power of attorney (POA) documents may protect a person's autonomy in future health care situations when the individual lacks decisional capacity. As such situations become naturally much more common in old age, we specifically aimed at providing information on (i) t...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-017-0482-8

    authors: Luck T,Rodriguez FS,Wiese B,van der Leeden C,Heser K,Bickel H,In der Schmitten J,Koenig HH,Weyerer S,Mamone S,Mallon T,Wagner M,Weeg D,Fuchs A,Brettschneider C,Werle J,Scherer M,Maier W,Riedel-Heller SG,AgeCoDe & Ag

    更新日期:2017-04-13 00:00:00

  • Lower dietary variety is a relevant factor for malnutrition in older Japanese home-care recipients: a cross-sectional study.

    abstract:BACKGROUND:Nutritional status of the older people is affected by various life-style factors. Although dietary habit is one of the life-style factors, it is unknown which of older home-care recipients' dietary habits are associated with malnutrition. The purpose of this study was to examine the association of dietary va...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-019-1206-z

    authors: Tsuji T,Yamamoto K,Yamasaki K,Hayashi F,Momoki C,Yasui Y,Ohfuji S,Fukushima W,Habu D

    更新日期:2019-07-26 00:00:00

  • Client, caregiver, volunteer, and therapist views on a voluntary supported group exercise programme for older adults with dementia.

    abstract:BACKGROUND:Existing group exercise programmes, or other services offered to maintain physical activity levels, are typically not developed specifically for older adults with dementia. The aim of this study was to gain knowledge about perceptions of a newly developed volunteer supported group exercise programme for olde...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-020-01632-6

    authors: Taraldsen K,Boulton E,Helbostad JL,Saltvedt I,Granbo R

    更新日期:2020-07-08 00:00:00

  • Symptom burden in community-dwelling older people with multimorbidity: a cross-sectional study.

    abstract:BACKGROUND:Globally, the population is ageing and lives with several chronic diseases for decades. A high symptom burden is associated with a high use of healthcare, admissions to nursing homes, and reduced quality of life. The aims of this study were to describe the multidimensional symptom profile and symptom burden ...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/1471-2318-15-1

    authors: Eckerblad J,Theander K,Ekdahl A,Unosson M,Wirehn AB,Milberg A,Krevers B,Jaarsma T

    更新日期:2015-01-05 00:00:00

  • Pilot comparative effectiveness study of surface perturbation treadmill training to prevent falls in older adults.

    abstract:BACKGROUND:Falls are the leading cause of fatal and non-fatal injuries among older adults. Exercise programs appear to reduce fall risk, but the optimal type, frequency, and duration of exercise is unknown. External perturbations such as tripping and slipping are a major contributor to falls, and task-specific perturba...

    journal_title:BMC geriatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2318-13-49

    authors: Lurie JD,Zagaria AB,Pidgeon DM,Forman JL,Spratt KF

    更新日期:2013-05-16 00:00:00

  • Medication supply to Residential Aged Care Facilities in Western Australia using a centralized medication chart to replace prescriptions.

    abstract:BACKGROUND:Current model of medication supply to Residential Aged Care Facilities (RACFs) in Australia is dependent on paper-based prescriptions. This study is aimed at assessing the use of a centralized medication chart as a prescription-less model for supplying medications to RACFs. METHODS:Two separate focus groups...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/1471-2318-12-25

    authors: Hoti K,Hughes J,Sunderland B

    更新日期:2012-07-11 00:00:00

  • Non-exercise based estimation of cardiorespiratory fitness is inversely associated with metabolic syndrome in a representative sample of Korean adults.

    abstract:BACKGROUND:This study investigated the association between non-exercise based estimation of cardiorespiratory fitness (eCRF) and metabolic syndrome (Mets) in Korean adults aged 18 years and older (13,400 women and 9885 men). METHODS:Data from the 2008 and 2011 Korea National Health and Nutrition Examination Surveys IV...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-020-01558-z

    authors: Lee I,Kim S,Kang H

    更新日期:2020-04-19 00:00:00

  • A prospective study of hepatic safety of statins used in very elderly patients.

    abstract:BACKGROUND:Statins play an important role in the care of patients with cardiovascular disease and have a good safety record in clinical practice. Hepatotoxicity is a barrier that limits the ability of primary care physicians to prescribe statins for patients with elevated liver transaminase values and/or underlying liv...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-019-1361-2

    authors: Guo M,Zhao J,Zhai Y,Zang P,Lv Q,Shang D

    更新日期:2019-12-16 00:00:00

  • Comprehensive pharmaceutical care to prevent drug-related readmissions of dependent-living elderly patients: a randomized controlled trial.

    abstract:BACKGROUND:Elderly patients are vulnerable to adverse drug reactions (ADRs). Drug-related readmissions (DRRs) can be a major consequence of ADR. Therefore, this study aimed to investigate the effects of a ward-based, comprehensive pharmaceutical care service on the occurrence of DRRs as the endpoint in dependent-living...

    journal_title:BMC geriatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12877-018-0814-3

    authors: Lenssen R,Schmitz K,Griesel C,Heidenreich A,Schulz JB,Trautwein C,Marx N,Fitzner C,Jaehde U,Eisert A

    更新日期:2018-06-04 00:00:00

  • The impact of frailty in aortic valve surgery.

    abstract:BACKGROUND:Frailty is a geriatric syndrome that diminishes potential functional recovery after any surgical procedure. Preoperative surgical risk assessment is crucial to calibrate the risk and benefit of cardiac surgery. The aim of this study was to test usefulness of FRAIL Scale and other surgical-risk-scales and ind...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-020-01716-3

    authors: Berastegui Garcia E,Camara Rosell ML,Moret Ruiz E,Casas Garcia I,Badia Gamarra S,Fernandez Gallego C,Delgado Ramis L,Julia Almill I,Llorens Ferrer A,Romero Ferrer B,Bayes Genis A,Muñoz Guijosa C

    更新日期:2020-10-27 00:00:00

  • Changes in executive functions and self-efficacy are independently associated with improved usual gait speed in older women.

    abstract:BACKGROUND:Improved usual gait speed predicts substantial reduction in mortality. A better understanding of the modifiable factors that are independently associated with improved gait speed would ensure that intervention strategies are developed based on a valid theoretical framework. Thus, we examined the independent ...

    journal_title:BMC geriatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2318-10-25

    authors: Liu-Ambrose T,Davis JC,Nagamatsu LS,Hsu CL,Katarynych LA,Khan KM

    更新日期:2010-05-19 00:00:00

  • Effectiveness of oral nutritional supplementation for older women after a fracture: rationale, design and study of the feasibility of a randomized controlled study.

    abstract:BACKGROUND:Malnutrition is a problem for many older people recovering from a hip and other major fractures. Oral supplementation with high calorie high protein nutrients is a simple intervention that may help older people with fractures to improve their recovery in terms of rehabilitation time, length of hospital stay ...

    journal_title:BMC geriatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2318-11-32

    authors: Cameron ID,Kurrle SE,Uy C,Lockwood KA,Au L,Schaafsma FG

    更新日期:2011-06-10 00:00:00

  • End-of-life care communications and shared decision-making in Norwegian nursing homes--experiences and perspectives of patients and relatives.

    abstract:BACKGROUND:Involving nursing home patients and their relatives in end-of-life care conversations and treatment decisions has recently gained increased importance in several Western countries. However, there is little knowledge about how the patients themselves and their next-of-kin look upon involvement in end-of-life ...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-015-0096-y

    authors: Gjerberg E,Lillemoen L,Førde R,Pedersen R

    更新日期:2015-08-19 00:00:00

  • Effectiveness and cost-effectiveness of an in-home respite care program in supporting informal caregivers of people with dementia: design of a comparative study.

    abstract:BACKGROUND:Frequent hospitalization and permanent nursing home placement not only affect the well-being of persons with dementia, but also place great financial strain on society. Therefore, it is important to create effective strategies to support informal caregivers so that they can continue to perform their demandin...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-016-0373-4

    authors: Vandepitte S,Van Den Noortgate N,Putman K,Verhaeghe S,Annemans L

    更新日期:2016-12-02 00:00:00

  • Potential neuroimaging biomarkers of pathologic brain changes in Mild Cognitive Impairment and Alzheimer's disease: a systematic review.

    abstract:BACKGROUND:Neuroimaging-biomarkers of Mild Cognitive Impairment (MCI) allow an early diagnosis in preclinical stages of Alzheimer's disease (AD). The goal in this paper was to review of biomarkers for Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD), with emphasis on neuroimaging biomarkers. METHODS:A syst...

    journal_title:BMC geriatrics

    pub_type: 杂志文章,评审

    doi:10.1186/s12877-016-0281-7

    authors: Ruan Q,D'Onofrio G,Sancarlo D,Bao Z,Greco A,Yu Z

    更新日期:2016-05-16 00:00:00

  • End-stage knee osteoarthritis with and without sarcopenia and the effect of knee arthroplasty - a prospective cohort study.

    abstract:BACKGROUND:Sarcopenia often accompanies osteoarthritis (OA), which is managed by total knee arthroplasty (TKA) in the late stage. Recent studies have suggested a higher risk of post-operative complications after TKA in sarcopenic OA subjects, but whether TKA can benefit them similar to non-sarcopenic subjects remains u...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-020-01929-6

    authors: Ho KK,Lau LC,Chau WW,Poon Q,Chung KY,Wong RM

    更新日期:2021-01-04 00:00:00

  • The association between anemia and falls in community-living women and men aged 65 years and older from the fifth Tromsø Study 2001-02: a replication study.

    abstract:BACKGROUND:Falls are common among elderly people, and the risk increase with age. Falls are associated with both health and social consequences for the patient, and major societal costs. Identification of risk factors should be investigated to prevent falls. Previous studies have shown anemia to be associated with incr...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-017-0689-8

    authors: Hopstock LA,Utne EB,Horsch A,Skjelbakken T

    更新日期:2017-12-27 00:00:00

  • A survey-based study of knowledge of Alzheimer's disease among health care staff.

    abstract:BACKGROUND:Continued aging of the population is expected to be accompanied by substantial increases in the number of people with dementia and in the number of health care staff required to care for them. Adequate knowledge about dementia among health care staff is important to the quality of care delivered to this vuln...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/1471-2318-13-2

    authors: Smyth W,Fielding E,Beattie E,Gardner A,Moyle W,Franklin S,Hines S,MacAndrew M

    更新日期:2013-01-02 00:00:00

  • Characteristics of outdoor falls among older people: a qualitative study.

    abstract:BACKGROUND:Falls are a major threat to older people's health and wellbeing. Approximately half of falls occur in outdoor environments but little is known about the circumstances in which they occur. We conducted a qualitative study to explore older people's experiences of outdoor falls to develop understanding of how t...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/1471-2318-13-125

    authors: Nyman SR,Ballinger C,Phillips JE,Newton R

    更新日期:2013-11-18 00:00:00

  • Immunosenescence in the nursing home elderly.

    abstract:BACKGROUND:To describe T-cell and natural killer (NK) cell phenotypes within nursing home elderly. METHODS:Nursing home elderly were recruited from four nursing homes in Hamilton, Ontario between September 2010 and December 2011. Healthy adults were recruited from McMaster University between September 2011 and Decembe...

    journal_title:BMC geriatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1186/1471-2318-14-50

    authors: Johnstone J,Millar J,Lelic A,Verschoor CP,Walter SD,Devereaux PJ,Bramson J,Loeb M

    更新日期:2014-04-17 00:00:00

  • Trajectories of physical function prior to death and brain neuropathology in a community-based cohort: the act study.

    abstract:BACKGROUND:Mechanisms linking cognitive and physical functioning in older adults are unclear. We sought to determine whether brain pathological changes relate to the level or rate of physical performance decline. METHODS:This study analyzed data from 305 participants in the autopsy subcohort of the prospective Adult C...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-017-0637-7

    authors: LaCroix AZ,Hubbard RA,Gray SL,Anderson ML,Crane PK,Sonnen JA,Zaslavsky O,Larson EB

    更新日期:2017-11-02 00:00:00

  • Use of anti-dementia drugs in home care and residential care and associations with neuropsychiatric symptoms: a cross-sectional study.

    abstract:BACKGROUND:The number of people with dementia is increasing alongside the aging population, and most of these patients manifest with neuropsychiatric symptoms (NPS). The objective of this study was to investigate anti-dementia drug use and its associations with NPS. METHODS:Questionnaires on demographic information, c...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-015-0102-4

    authors: Kuronen M,Koponen H,Nykänen I,Karppi P,Hartikainen S

    更新日期:2015-08-13 00:00:00

  • The experience of lived space in persons with dementia: a systematic meta-synthesis.

    abstract:BACKGROUND:Identifying how persons with dementia experience lived space is important for enabling supportive living environments and creating communities that compensate for the fading capabilities of these persons. Several single studies have explored this topic; however, few studies have attempted to explicitly revie...

    journal_title:BMC geriatrics

    pub_type: 杂志文章,meta分析

    doi:10.1186/s12877-018-0728-0

    authors: Førsund LH,Grov EK,Helvik AS,Juvet LK,Skovdahl K,Eriksen S

    更新日期:2018-02-01 00:00:00

  • Reducing the use of physical restraints in home care: development and feasibility testing of a multicomponent program to support the implementation of a guideline.

    abstract:BACKGROUND:A validated evidence-based guideline was developed to reduce physical restraint use in home care. However, the implementation of guidelines in home care is challenging. Therefore, this study aims to systematically develop and evaluate a multicomponent program for the implementation of the guideline for reduc...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-020-01946-5

    authors: Vandervelde S,Scheepmans K,Milisen K,van Achterberg T,Vlaeyen E,Flamaing J,Dierckx de Casterlé B

    更新日期:2021-01-25 00:00:00

  • Stroke with atrial fibrillation or atrial flutter: a descriptive population-based study from the Brest stroke registry.

    abstract:BACKGROUND:In the 1990s, epidemiological studies estimated the prevalence of stroke caused by atrial fibrillation (AF) at about 15 %. Given the aging population, there is a rise in the number of AF patients. AF prevention guidelines based on clinical practice and the literature have been published and updated since 200...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-015-0067-3

    authors: Jannou V,Timsit S,Nowak E,Rouhart F,Goas P,Merrien FM,Viakhireva-Dovganyuk I,Tirel-Badets A,Gentric A

    更新日期:2015-06-11 00:00:00

  • Exploration of 27 plasma immune markers: a cross-sectional comparison of 64 old psychiatric inpatients having unipolar major depression and 18 non-depressed old persons.

    abstract:BACKGROUND:The prevalence of major depression (MD) according to population studies is the same for old (65 years and older) and younger adults. In contrast, an elevated proportion of old MD patients are hospitalized compared to younger adults with MD, indicating a need to expand the characteristics of old inpatients wi...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-018-0836-x

    authors: Gaarden TL,Engedal K,Benth JŠ,Larsen M,Lorentzen B,Mollnes TE,Bjølseth TM,Castellheim A

    更新日期:2018-06-25 00:00:00

  • Health, wellbeing and nutritional status of older people living in UK care homes: an exploratory evaluation of changes in food and drink provision.

    abstract:BACKGROUND:Food and drink are important determinants of physical and social health in care home residents. This study explored whether a pragmatic methodology including routinely collected data was feasible in UK care homes, to describe the health, wellbeing and nutritional status of care home residents and assess effe...

    journal_title:BMC geriatrics

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1186/1471-2318-10-28

    authors: Kenkmann A,Price GM,Bolton J,Hooper L

    更新日期:2010-05-27 00:00:00

  • Association between rural-to-urban migration and the cognitive aging trajectories of older Chinese adults: results from a prospective cohort analysis.

    abstract:BACKGROUND:Increasingly, older Chinese adults from rural areas are moving to urban areas to live with their children who have already migrated to these areas. However, few studies have examined this pattern of migration and its effects on cognitive function. We aimed to investigate the association between domestic rura...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-020-01772-9

    authors: Xie J,Liao J,Zhang J,Gu J

    更新日期:2020-09-21 00:00:00

  • Home based exercise to improve turning and mobility performance among community dwelling older adults: protocol for a randomized controlled trial.

    abstract:BACKGROUND:Turning is a common activity for older people, and is one of the activities commonly associated with falls during walking. Falls that occur while walking and turning have also been associated with an increased risk of hip fracture in older people. Despite the importance of stability during turning, there has...

    journal_title:BMC geriatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2318-14-100

    authors: Asmidawati A,Hamid TA,Hussain RM,Hill KD

    更新日期:2014-09-08 00:00:00

  • Older age and frailty are the chief predictors of mortality in COVID-19 patients admitted to an acute medical unit in a secondary care setting- a cohort study.

    abstract:BACKGROUND:There is a need for more observational studies across different clinical settings to better understand the epidemiology of the novel COVID-19 infection. Evidence on clinical characteristics of COVID-19 infection is scarce in secondary care settings in Western populations. METHODS:We describe the clinical ch...

    journal_title:BMC geriatrics

    pub_type: 杂志文章

    doi:10.1186/s12877-020-01803-5

    authors: Chinnadurai R,Ogedengbe O,Agarwal P,Money-Coomes S,Abdurrahman AZ,Mohammed S,Kalra PA,Rothwell N,Pradhan S

    更新日期:2020-10-16 00:00:00