Abstract:
BACKGROUND:The increasing use of common data elements (CDEs) in numerous research projects and clinical applications has made it imperative to create an effective classification scheme for the efficient management of these data elements. We applied high-level integrative modeling of entire clinical documents from real-world practice to create the Clinical MetaData Ontology (CMDO) for the appropriate classification and integration of CDEs that are in practical use in current clinical documents. METHODS:CMDO was developed using the General Formal Ontology method with a manual iterative process comprising five steps: (1) defining the scope of CMDO by conceptualizing its first-level terms based on an analysis of clinical-practice procedures, (2) identifying CMDO concepts for representing clinical data of general CDEs by examining how and what clinical data are generated with flows of clinical care practices, (3) assigning hierarchical relationships for CMDO concepts, (4) developing CMDO properties (e.g., synonyms, preferred terms, and definitions) for each CMDO concept, and (5) evaluating the utility of CMDO. RESULTS:We created CMDO comprising 189 concepts under the 4 first-level classes of Description, Event, Finding, and Procedure. CMDO has 256 definitions that cover the 189 CMDO concepts, with 459 synonyms for 139 (74.0%) of the concepts. All of the CDEs extracted from 6 HL7 templates, 25 clinical documents of 5 teaching hospitals, and 1 personal health record specification were successfully annotated by 41 (21.9%), 89 (47.6%), and 13 (7.0%) of the CMDO concepts, respectively. We created a CMDO Browser to facilitate navigation of the CMDO concept hierarchy and a CMDO-enabled CDE Browser for displaying the relationships between CMDO concepts and the CDEs extracted from the clinical documents that are used in current practice. CONCLUSIONS:CMDO is an ontology and classification scheme for CDEs used in clinical documents. Given the increasing use of CDEs in many studies and real-world clinical documentation, CMDO will be a useful tool for integrating numerous CDEs from different research projects and clinical documents. The CMDO Browser and CMDO-enabled CDE Browser make it easy to search, share, and reuse CDEs, and also effectively integrate and manage CDEs from different studies and clinical documents.
journal_name
BMC Med Inform Decis Makjournal_title
BMC medical informatics and decision makingauthors
Kim HH,Park YR,Lee KH,Song YS,Kim JHdoi
10.1186/s12911-019-0877-xsubject
Has Abstractpub_date
2019-08-20 00:00:00pages
166issue
1issn
1472-6947pii
10.1186/s12911-019-0877-xjournal_volume
19pub_type
杂志文章abstract:BACKGROUND:Early alarm of hypoglycemia, detection of asymptomatic hypoglycemia, and effective control of blood glucose fluctuation make a great contribution to diabetic treatment. In this study, we designed a multi-level hypoglycemia early alarm system to mine potential information in Continuous Glucose Monitoring (CGM...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-021-01389-x
更新日期:2021-01-21 00:00:00
abstract:BACKGROUND:Mobile phone technology has demonstrated the potential to improve health service delivery, but there is little guidance to inform decisions about acquiring and implementing mHealth technology at scale in health systems. Using the case of community-based health services (CBS) in South Africa, we apply a frame...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-12-123
更新日期:2012-11-05 00:00:00
abstract:BACKGROUND:Electronic patient portals are increasingly being implemented, also in (haemato) oncology. However, portal usage is low and depends on user and provider engagement. We explored wishes, expectations and thoughts of patients with a haematologic malignancy and their physicians with regard to the electronic pati...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-019-0868-y
更新日期:2019-07-11 00:00:00
abstract:BACKGROUND:Electronic health records are now widely adopted in medical and behavioral health settings. While they have the potential to improve the quality of care, the research findings on their impact on clinical practice and outcomes have been mixed. This study explores how the electronic health record and its stage...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12911-019-0897-6
更新日期:2019-08-22 00:00:00
abstract:BACKGROUND:Cardiac diseases represent the leading cause of sudden death worldwide. During the development of cardiac diseases, the left ventricle (LV) changes obviously in structure and function. LV motion estimation plays an important role for diagnosis and treatment of cardiac diseases. To estimate LV motion accurate...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-017-0560-z
更新日期:2017-12-20 00:00:00
abstract:BACKGROUND:Machine-learning classifiers mostly offer good predictive performance and are increasingly used to support shared decision-making in clinical practice. Focusing on performance and practicability, this study evaluates prediction of patient-reported outcomes (PROs) by eight supervised classifiers including a l...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-018-0731-6
更新日期:2019-01-08 00:00:00
abstract:BACKGROUND:Information extraction techniques that get structured representations out of unstructured data make a large amount of clinically relevant information about patients accessible for semantic applications. These methods typically rely on standardized terminologies that guide this process. Many languages and cli...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-015-0215-x
更新日期:2015-11-12 00:00:00
abstract:BACKGROUND:Prostate cancer (PCa) represents a significant healthcare problem. The critical clinical question is the need for a biopsy. Accurate risk stratification of patients before a biopsy can allow for individualised risk stratification thus improving clinical decision making. This study aims to build a risk calcul...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-020-01174-2
更新日期:2020-07-03 00:00:00
abstract:BACKGROUND:Biofuels produced from biomass are considered to be promising sustainable alternatives to fossil fuels. The conversion of lignocellulose into fermentable sugars for biofuels production requires the use of enzyme cocktails that can efficiently and economically hydrolyze lignocellulosic biomass. As many fungi ...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-12-S1-S5
更新日期:2012-04-30 00:00:00
abstract:BACKGROUND:We developed Supportive care Prioritization, Assessment and Recommendations for Kids (SPARK), a web-based application designed to facilitate symptom screening by children receiving cancer treatments and access to supportive care clinical practice guidelines primarily by healthcare providers. The objective wa...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-018-0715-6
更新日期:2019-01-10 00:00:00
abstract:BACKGROUND:Patients with a prolonged intensive care unit (ICU) length of stay account for a disproportionate amount of resource use. Early identification of patients at risk for a prolonged length of stay can lead to quality enhancements that reduce ICU stay. This study developed and validated a model that identifies p...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-10-27
更新日期:2010-05-13 00:00:00
abstract:BACKGROUND:Congestive heart failure is one of the most common reasons those aged 65 and over are hospitalized in the United States, which has caused a considerable economic burden. The precise prediction of hospitalization caused by congestive heart failure in the near future could prevent possible hospitalization, opt...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-019-0734-y
更新日期:2019-01-31 00:00:00
abstract:BACKGROUND:Electronic health records provide access to an unprecedented amount of clinical data for research that can accelerate the development of effective medical practices. However it is important to protect patient confidentiality, as many medical conditions are stigmatized and disclosure could result in personal ...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-11-70
更新日期:2011-11-10 00:00:00
abstract:BACKGROUND:Since the introduction of electronic nursing documentation systems, its implementation in recent years has increased rapidly in Germany. The objectives of such systems are to save time, to improve information handling and to improve quality. To integrate IT in the daily working processes, the employee is the...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章,meta分析,评审
doi:10.1186/1472-6947-14-54
更新日期:2014-06-20 00:00:00
abstract:BACKGROUND:Identifying subtypes of complex diseases such as cancer is the very first step toward developing highly customized therapeutics on such diseases, as their origins significantly vary even with similar physiological characteristics. There have been many studies to recognize subtypes of various cancer based on ...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-016-0295-2
更新日期:2016-07-18 00:00:00
abstract:BACKGROUND:Effective use of a patient decision aid (PtDA) can be affected by the user's health literacy and the PtDA's characteristics. Systematic reviews of the relevant literature can guide PtDA developers to attend to the health literacy needs of patients. The reviews reported here aimed to assess: METHODS:We revie...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章,评审
doi:10.1186/1472-6947-13-S2-S10
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The objective of this study was to explore the use and perceptions of a local Severe Acute Respiratory Syndrome (SARS) Extranet and its potential to support future information and communication applications. The SARS Extranet was a single, managed electronic and limited access system to manage local, provinc...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-5-17
更新日期:2005-06-20 00:00:00
abstract:BACKGROUND:Electronic medical records contain information of value for research, but contain identifiable and often highly sensitive confidential information. Patient-identifiable information cannot in general be shared outside clinical care teams without explicit consent, but anonymisation/de-identification allows res...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章,评审
doi:10.1186/s12911-017-0437-1
更新日期:2017-04-26 00:00:00
abstract:BACKGROUND:New Specific Application Domain (SAD) heuristics or design principles are being developed to guide the design and evaluation of mobile applications in a bid to improve on the usability of these applications. This is because the existing heuristics are rather generic and are often unable to reveal a large num...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-018-0718-3
更新日期:2019-01-09 00:00:00
abstract:BACKGROUND:Although fecal hemoglobin concentration (f-Hb) was highly associated with the risk of colorectal neoplasms, current studies on this subject are hampered by skewedness of the data and the ordinal property of f-Hb has not been well studied yet. Our aim was to develop a quantile-based method to estimate adjuste...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-019-0812-1
更新日期:2019-05-02 00:00:00
abstract:BACKGROUND:Informatics for Integrating Biology and the Bedside (i2b2) is an open source clinical data analytics platform used at over 200 healthcare institutions for querying patient data. The i2b2 platform has several components with numerous dependencies and configuration parameters, which renders the task of install...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-018-0646-2
更新日期:2018-07-16 00:00:00
abstract:BACKGROUND:Patients undergoing heart surgery continue to be the largest demand on blood transfusions. The need for transfusion is based on the risk of complications due to poor cell oxygenation, however large transfusions are associated with increased morbidity and risk of mortality in heart surgery patients. The aim o...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-11-44
更新日期:2011-06-21 00:00:00
abstract:BACKGROUND:Large healthcare databases, with their ability to collect many variables from daily medical practice, greatly enable health services research. These longitudinal databases provide large cohorts and longitudinal time frames, allowing for highly pragmatic assessment of healthcare delivery. The purpose of this ...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-018-0588-8
更新日期:2018-01-31 00:00:00
abstract:BACKGROUND:Clinical notes such as discharge summaries have a semi- or unstructured format. These documents contain information about diseases, treatments, drugs, etc. Extracting meaningful information from them becomes challenging due to their narrative format. In this context, we aimed to compare the automatic extract...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-018-0654-2
更新日期:2018-09-14 00:00:00
abstract:BACKGROUND:Diagnostic accuracy might be improved by algorithms that searched patients' clinical notes in the electronic health record (EHR) for signs and symptoms of diseases such as multiple sclerosis (MS). The focus this study was to determine if patients with MS could be identified from their clinical notes prior to...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-017-0418-4
更新日期:2017-02-28 00:00:00
abstract:BACKGROUND:A pilot experimentation of a telemonitoring system for chronic care patients is conducted in the Bilbao Primary Care Health Region (Basque Country, Spain). It seems important to understand the factors related to healthcare professionals' acceptance of this new technology in order to inform its extension to t...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-12-139
更新日期:2012-11-30 00:00:00
abstract:BACKGROUND:The linkage of records which refer to the same entity in separate data collections is a common requirement in public health and biomedical research. Traditionally, record linkage techniques have required that all the identifying data in which links are sought be revealed to at least one party, often a third ...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-4-9
更新日期:2004-06-28 00:00:00
abstract:BACKGROUND:Prior studies demonstrate the suitability of natural language processing (NLP) for identifying pneumonia in chest radiograph (CXR) reports, however, few evaluate this approach in intensive care unit (ICU) patients. METHODS:From a total of 194,615 ICU reports, we empirically developed a lexicon to categorize...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-13-90
更新日期:2013-08-15 00:00:00
abstract:BACKGROUND:Women diagnosed with early breast cancer (stage I or II) can be offered the choice between mastectomy or breast conservation surgery with radiotherapy due to equivalence in survival rates. A wide variation in the surgical management of breast cancer and a lack of theoretically guided research on this issue h...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-13-92
更新日期:2013-08-20 00:00:00
abstract:BACKGROUND:Comparing outcomes between hospitals requires consideration of patient factors that could account for any observed differences. Adjusting for comorbid conditions is common when studying outcomes following cancer surgery, and a commonly used measure is the Charlson comorbidity index. Other measures of patient...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-015-0175-1
更新日期:2015-07-15 00:00:00