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Application of a novel sex independent anthropometric index, termed angle index, in relation to type 2 diabetes: a Trinidadian case-control study.

Abstract：

OBJECTIVE:To develop a novel sex independent anthropometric index, termed as angle index, related to type 2 diabetes. DESIGN:Case-control. PARTICIPANTS:The study comprised 121 participants and were divided into two groups. One group had no form of diabetes and served as controls (n=50). The other group had the condition of type 2 diabetes (n=71). 31% (n=37) of the subjects were male and 69% (n=84) were female. 62% (n=75) of the subjects were of East Indian ethnicity, 28% (n=34) were of African ethnicity and 10% (n=12) were of mixed ethnicity. SETTING:Participants of the study were from the island of Trinidad, located in the Caribbean. Patients in the study were selected at random from hospital records. PRIMARY OUTCOME MEASURE:It was hypothesised that the mean angle index of patients with type 2 diabetes would be higher than the mean angle index of patients without type 2 diabetes. RESULTS:Patients with type 2 diabetes had a significantly higher angle index value as compared with controls (p<0.001). Angle index was the superior sex independent anthropometric index in relation to type 2 diabetes (area under the curve=0.72; p<0.001) as compared with other sex independent variables. Angle index correlated with glycated haemoglobin (rs=0.28, p=0.003) and fasting blood glucose (rs=0.31, p=0.001) levels. Patients with type 2 diabetes were four times more likely to have an angle index greater than 184° (OR 4.2, 95% CI 1.8 to 9.9) as compared with controls. CONCLUSION:Angle index was a superior sex independent index for discriminating between patients with and without type 2 diabetes, as compared with waist circumference, abdominal volume index, conicity index, blood pressure readings, triglyceride levels and very low-density lipoprotein levels.

journal_name

BMJ Open

journal_title

BMJ open

authors

Ramnanansingh TG,Nayak SB

doi

10.1136/bmjopen-2018-024029

subject

Has Abstract

pub_date

2019-02-19 00:00:00

pages

e024029

issue

2

issn

2044-6055

pii

bmjopen-2018-024029

journal_volume

9

pub_type

杂志文章

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