Abstract:
BACKGROUND:The burden of substance misuse in developing countries is large and increasing, with negative consequences for physical and psychological health. Substance use disorders and psychological distress commonly co-exist, however few studies have examined this relationship in developing countries, including Nepal. Our aim was to investigate the prevalence of psychological distress symptoms and associated factors among patients with substance use disorders attending drug rehabilitation centers in Nepal. METHODS:We conducted a cross-sectional study including 180 patients attending drug rehabilitation centers in the Kathmandu Valley region of Nepal. We used the 6-item Kessler scale (K6) to measure symptoms of psychological distress, and data on socio-demographics, behavioral and psychosocial factors. Multivariable analyses were used to identify factors associated with distress. RESULTS:The prevalence of high psychological distress symptoms among patients with substance use disorder was 51.1 %. The mean score found on the K6 was 12.22 (SD = 5.87). Outcomes of multivariable analyses demonstrated various factors associated with symptoms of psychological distress, including age (β = -0.122, 95 % CI = -0.218; -0.026), education (β =2.694, 95 % CI = 0.274; 5.115), severity of drug abuse (Drug Abuse Screening Test-10-DAST10)(β = 0.262, 95 % CI = 0.022;0.502), and family functioning (Adaptability, Partnership, Growth, Affection and Resolve-APGAR) (β = -0.525, 95 % CI = -0.787; -0.264). CONCLUSIONS:High psychological distress symptoms are common in patients with substance use disorder in Nepal. Demographics (age, education), behavioral (drug abuse severity), and psychosocial factors (family functionality) were associated with psychological distress symptoms. If confirmed by future longitudinal studies such characteristics may assist in identifying groups at risk for co-morbid psychological distress symptoms among patients with substance use disorders. Future treatment approaches for substance use disorders should address co-existing mental illness in Nepal.
journal_name
BMC Psychiatryjournal_title
BMC psychiatryauthors
Gyawali B,Choulagai BP,Paneru DP,Ahmad M,Leppin A,Kallestrup Pdoi
10.1186/s12888-016-1003-6subject
Has Abstractpub_date
2016-09-08 00:00:00pages
314issue
1issn
1471-244Xpii
10.1186/s12888-016-1003-6journal_volume
16pub_type
杂志文章相关文献
BMC Psychiatry文献大全abstract:BACKGROUND:Social anxiety disorder (SAD) is one of the most common anxiety disorders. The efficacy of cognitive behaviour therapy (CBT) has been examined but to date its effects on Quality of Life (QoL) have not been appropriately evaluated especially in the long term.The study aimed to examine, in the long term, what ...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/1471-244X-10-81
更新日期:2010-10-14 00:00:00
abstract:BACKGROUND:Administrative data are increasingly used to conduct research on depression and inform health services and health policy. Depression surveillance using administrative data is an alternative to surveys, which can be more resource-intensive. The objectives of this study were to: (1) systematically review the l...
journal_title:BMC psychiatry
pub_type: 杂志文章,评审
doi:10.1186/s12888-014-0289-5
更新日期:2014-10-17 00:00:00
abstract:BACKGROUND:Depression is the most prevalent psychiatric disorder among people living with HIV (PLWHIV) and is associated with poor quality of life, additional comorbidities, disability, unemployment, poorer therapeutic outcomes and risky behaviors. The present systematic review and meta-analysis aims to systematically ...
journal_title:BMC psychiatry
pub_type: 杂志文章,meta分析
doi:10.1186/s12888-018-1835-3
更新日期:2018-08-15 00:00:00
abstract:BACKGROUND:Major depressive disorder (MDD) is a major public health burden in conflict areas. However, it is not known for how long and by how much the observed high rates of MDD seen in conflict settings persist into the post-conflict period. METHODS:A cross sectional survey was employed seven years after the conflic...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-015-0423-z
更新日期:2015-03-14 00:00:00
abstract:BACKGROUND:Family members who care for patients with severe mental illness experience emotional distress and report a higher incidence of mental illness than those in the general population. They report feeling inadequately prepared to provide the necessary practical and emotional support for these patients. The MAT tr...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-018-1669-z
更新日期:2018-03-27 00:00:00
abstract:BACKGROUND:Abnormalities in vocal expression during a depressed episode have frequently been reported in people with depression, but less is known about if these abnormalities only exist in special situations. In addition, the impacts of irrelevant demographic variables on voice were uncontrolled in previous studies. T...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-019-2300-7
更新日期:2019-10-15 00:00:00
abstract:BACKGROUND:Economic crises and unemployment have profound impact on mental health and well-being. Main goal of the Healthy Employment (HE) project is to enhance intersectoral actions promoting mental health among unemployed, namely through the implementation and effectiveness-evaluation of short-term and sustainable gr...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-017-1416-x
更新日期:2017-07-19 00:00:00
abstract:BACKGROUND:In recent years, Voluntary Assisted Return Programmes (VARPs) have received increasing funding as a potential way of reducing the number of refugees in EU member states. A number of factors may affect the mental well-being of returnees. These include adjustment to the home country following return, difficult...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/1471-244X-8-88
更新日期:2008-11-10 00:00:00
abstract:BACKGROUND:Severe mental disorders like psychotic disorders including schizophrenia and schizoaffective disorders have a 12-month-prevalence of 2.6, bipolar disorders of 1.5% in Germany. The relapse risk is high; so many patients need intensive monitoring and lifelong treatment. A high medication adherence is essential...
journal_title:BMC psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/s12888-015-0659-7
更新日期:2015-11-04 00:00:00
abstract:BACKGROUND:There is a significant treatment gap for patients with depression. A third of sufferers never seek help, and the vast majority of those who do only do so after considerable delay. Little is understood regarding poor help-seeking rates amongst people with depression, with existing research mainly focussed on ...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/1471-244X-12-164
更新日期:2012-10-02 00:00:00
abstract:BACKGROUND:The optimal treatment of patients with substance use disorders (SUDs) requires an awareness of their comorbid mental disorders and vice versa. The prevalence of comorbidity in first-time-admitted SUD patients has been insufficiently studied. Diagnosing comorbidity in substance users is complicated by symptom...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/1471-244X-11-25
更新日期:2011-02-12 00:00:00
abstract:BACKGROUND:Idiopathic pulmonary arterial hypertension (IPAH) is a progressive and fatal cardiovascular disease if left untreated. In patients with IPAH with psychiatric illness or other complications, careful attention is required when administering medical therapies that may affect their hemodynamics. Patients sufferi...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-016-0835-4
更新日期:2016-05-06 00:00:00
abstract:BACKGROUND:Schizophrenia is associated with increased cardiovascular morbidity and mortality. Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of the nitric oxide synthase, and the L-arginine:ADMA ratio are markers of endothelial dysfunction that predict mortality and adverse outcome in a range of cardiovasc...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-015-0455-4
更新日期:2015-04-03 00:00:00
abstract:BACKGROUND:Accurate diagnosis of delirium is very important for prevention and treatment. Present study was designed to validate the 3-Minute Diagnostic Interview for CAM-defined Delirium Chinese version (3D-CAM-CN) in surgical ICU patients. METHODS:In this prospective diagnostic study, the 3D-CAM was translated into ...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-020-02544-w
更新日期:2020-03-24 00:00:00
abstract:BACKGROUND:While considerable progress has been made in exploring the psychological, the neural, and the neurochemical dimensions of OCD separately, their interplay is still an open question, especially their changes during psychotherapy. METHODS:Seventeen patients were assessed at these three levels by psychological ...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-020-02913-5
更新日期:2020-11-25 00:00:00
abstract:BACKGROUND:The World Health Organization (WHO) has included comorbidity between depression and a chronic disease among the 10 leading global health priorities. Although there is a high prevalence of multimorbidity, health care systems are mainly designed for the management of individual diseases. Given the difficulty i...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-019-2037-3
更新日期:2019-02-11 00:00:00
abstract:BACKGROUND:Stigma against mental illness cuts across all age, religion, ethnic origin or socio-economic status. Similarly, self-stigma among psychiatric patients is also prevalent worldwide. The consequences of self-stigma are low self-esteem, increased severity of symptoms, low treatment adherence, increased rate of s...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-019-2344-8
更新日期:2019-11-07 00:00:00
abstract:BACKGROUND:The purpose of the study was to determine the effectiveness and tolerability of quetiapine as a maintenance treatment preventing against relapse or recurrence of acute mood episodes in adolescent patients diagnosed with bipolar disorder. METHODS:Consenting patients meeting DSM-IV lifetime criteria for a bip...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/1471-244X-9-4
更新日期:2009-02-06 00:00:00
abstract:BACKGROUND:Although there is some quantitative evidence to suggest the benefits of group psychoeducation for people with bipolar disorder, patients' perspectives and experiences of group psychoeducation require in-depth exploration to enable us to better understand the feasibility, acceptability and impact of these int...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-015-0556-0
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Clinical evidence has long suggested there may be heterogeneity in the patterns and predictors of common mood and anxiety disorders; however, epidemiologic studies have generally treated these outcomes as homogenous entities. The objective of this study was to systematically review the epidemiologic evidence...
journal_title:BMC psychiatry
pub_type: 杂志文章,评审
doi:10.1186/1471-244X-9-31
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:For around a third of people with a diagnosis of schizophrenia, the condition proves to respond poorly to treatment with many typical and atypical antipsychotics. This is commonly referred to as treatment-resistant schizophrenia. Clozapine is the only antipsychotic with convincing efficacy for people whose s...
journal_title:BMC psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12888-016-0983-6
更新日期:2016-08-05 00:00:00
abstract:BACKGROUND:Farmers are a vulnerable population for developing depression or other mental health disorders due to a variety of risk factors in their work context. Beyond face-to-face resources, preventive internet- and tele-based interventions could extend available treatment options to overcome barriers to care. The Ge...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-020-02800-z
更新日期:2020-08-27 00:00:00
abstract:BACKGROUND:Generalized Anxiety Disorder (GAD), characterized by excessive and uncontrollable worry, has a negative impact on the health, well-being, and functioning of older adults. Cognitive behavioral therapy has demonstrated efficacy in reducing anxiety and worry in older adults, but the generalizability of these fi...
journal_title:BMC psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-244X-14-34
更新日期:2014-02-08 00:00:00
abstract:BACKGROUND:Suicidal ideation is common in patients suffering from panic disorder. The present study investigated rates of suicidal ideation and risk factors for suicidal ideation in a sample of primary care patients suffering from panic disorder with or without agoraphobia. METHODS:A total of N = 296 patients [n = 215...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-018-1894-5
更新日期:2018-09-24 00:00:00
abstract:BACKGROUND:Attention Deficit Hyperactivity Disorder (ADHD) is a genetically influenced condition although indicators of environmental risk including maternal smoking during pregnancy, low birth weight and low social class have also been found to be associated with the disorder. ADHD is a phenotypically heterogeneous di...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/1471-244X-7-26
更新日期:2007-06-20 00:00:00
abstract:BACKGROUND:Despite the emergence of mental health problems during adolescence and early adulthood, many young people encounter difficulties accessing appropriate services. In response to this gap, the Australian Government recently established new enhanced primary care services (headspace) that target young people with...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/1471-244X-12-96
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Depression and anxiety result in psychological distress, which can further affect mental status and quality of life in stroke patients. Exploring the associations between positive psychological variables and symptoms of psychological distress following stroke is of great significance for further psychologica...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-019-2368-0
更新日期:2019-12-03 00:00:00
abstract:BACKGROUND:Biological factors influencing individual response to drugs are being extensively studied in psychiatry. Strikingly, there are few studies addressing social and cultural differences in attitudes toward psychotropic medications. The objective of this study was to investigate ethno-culturally determined belief...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/1471-244X-8-55
更新日期:2008-07-09 00:00:00
abstract:BACKGROUND:Although previous studies suggest a high frequency of psychotic symptoms in DSM-IV Borderline Personality Disorder (BPD) there is currently no consensus on their prevalence and characteristics (type, frequency, duration, location etc.). Similarly, there are few papers addressing psychotic reactivity, the cru...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-014-0239-2
更新日期:2014-10-03 00:00:00
abstract:BACKGROUND:The clinical utility of the existing apps for people with eating disorders (EDs) is not clear. The TCApp has been specifically developed for people with EDs, is based on the principles of Cognitive Behavioural Treatment (CBT) and allows a bidirectional link between the patient and the therapist. The objectiv...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-018-1664-4
更新日期:2018-05-02 00:00:00