Emergence of influenza A (H1N1)pdm09 genogroup 6B and drug resistant virus, India, January to May 2015.

Abstract:

:To investigate the aetiology of the 2015 A(H1N1)pdm09 influenza outbreak in India, 1,083 nasopharyngeal swabs from suspect patients were screened for influenza A(H1N1)pdm09 in the state of Madhya Pradesh. Of 412 positive specimens, six were further characterised by phylogenetic analysis of haemagglutinin (HA) sequences revealing that they belonged to genogroup 6B. A new mutation (E164G) was observed in HA2 of two sequences. Neuraminidase genes in two of 12 isolates from fatal cases on prior oseltamivir treatment harboured the H275Y mutation.

journal_name

Euro Surveill

authors

Parida M,Dash PK,Kumar JS,Joshi G,Tandel K,Sharma S,Srivastava A,Agarwal A,Saha A,Saraswat S,Karothia D,Malviya V

doi

10.2807/1560-7917.ES.2016.21.5.30124

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

6-11

issue

5

eissn

1025-496X

issn

1560-7917

pii

30124

journal_volume

21

pub_type

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