Abstract:
BACKGROUND:The most common malignant salivary gland tumors that affect both adult and children is mucoepidermoid carcinoma. It usually affects both minor and major salivary glands but parotid gland is considering the most common site in which this tumor arises. CD44, a trans-membrane glycoprotein, is an adhesion molecule of cell surface that play a role in the connections between cell-cell and cell-matrix. Many malignant tumors express high levels of CD44, thus, CD44 may be used as an indicator of aggressive behavior of some human malignancy. We evaluate CD44 expression in different grades of mucoepidermoid carcinoma and determine whether expression of CD44 can be used to predict tumor aggressiveness. METHODS:Fifteen cases of mucoepidermoid carcinoma were retrieved from the oral pathology archives and grouped according to the histological grade as well as the clinical behavior regarding metastases and/or recurrence. Tissue sections were immunohistochemically stained for CD44. CD44 staining was scored for intensity and proportion of cells stained. RESULTS:A higher proportion of high-grade tumor tissues showed moderate or strong CD44 staining compared to low-grade tumors. Additionally, CD44 expression was stronger in tumors from patients with recurrences or metastases, but theses differences were not statistically significant. CONCLUSION:Our result showed that mucoepidermoid carcinomas are immunohistochemistry positive to CD44 compare to normal. A trend of CD44 expression associated with different histological grading and aggressive behavior of this tumor.
journal_name
Head Face Medjournal_title
Head & face medicineauthors
Binmadi N,Elsissi A,Elsissi Ndoi
10.1186/s13005-016-0102-4subject
Has Abstractpub_date
2016-01-29 00:00:00pages
8issn
1746-160Xpii
10.1186/s13005-016-0102-4journal_volume
12pub_type
杂志文章abstract:BACKGROUND:The apparent interactions between the mechanisms of action of non-steroidal anti-inflammatory drugs (NSAIDS) and steroids suggest that co-therapy may provide beneficial inflammatory and pain relief in the absence of side effects. The aim of the study was to compare the effect of co-administered dexamethasone...
journal_title:Head & face medicine
pub_type: 杂志文章,随机对照试验
doi:10.1186/1746-160X-1-11
更新日期:2005-11-07 00:00:00
abstract:INTRODUCTION:The aim of the study was to compare the detectability of neck vessels with contrast enhanced magnetic resonance angiography (MRA) in the setting of a whole-body MRA and multislice computed tomography angiography (CTA) for preoperative vascular mapping of head and neck. METHODS:In 20 patients MRA was perfo...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/1746-160X-10-16
更新日期:2014-05-12 00:00:00
abstract:INTRODUCTION:Various surgical procedures are available to correct paralytic ectropion, which are applied in irreversible facial paresis. Problems occur when facial paresis has an unclear prognosis, since surgery of the lower eyelid is usually irreversible. We propose a simple method to correct temporary ectropion in fa...
journal_title:Head & face medicine
pub_type: 临床试验,杂志文章
doi:10.1186/1746-160X-4-12
更新日期:2008-07-21 00:00:00
abstract:BACKGROUND:Periodontal health is of great concern for periodontists and orthodontists in the inter-disciplinary management of patients with bimaxillary protrusion. The aim of present study is to investigate changes in the alveolar bone in the maxillary incisor region and to explore its relationship with displacement of...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/s13005-020-00242-2
更新日期:2020-11-20 00:00:00
abstract:BACKGROUND:Schwannomas are uncommon benign tumors of the external auditory canal. The clinical features, the differential diagnosis, and the surgical treatment of these lesions are discussed. CASE PRESENTATION:A 51-year-old patient presented with a mass obliterating the external auditory meatus. Excisional biopsy was ...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/1746-160X-3-6
更新日期:2007-01-15 00:00:00
abstract:BACKGROUND:Functional and aesthetic mandibular reconstruction after ablative tumor surgery continues to be a challenge even after the introduction of microvascular bone transfer. Complex microvascular reconstruction of the resection site requires accurate preoperative planning. In the recent past, bone graft and fixati...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/1746-160X-3-5
更新日期:2007-01-15 00:00:00
abstract:BACKGROUND:A pneumatized superior turbinate is a rare cause of headache. Nasal endoscopy alone, does not provide us with adequate information for this inaccessible area of the superior nasal cavity. A coronal computed tomography (CT) must be obtained to confirm the diagnosis. CASE PRESENTATION:We present a 40-year-old...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/1746-160X-3-3
更新日期:2007-01-09 00:00:00
abstract::Potential applications for gene-based tissue engineering therapies in the oral and maxillofacial complex include the delivery of growth factors for periodontal regeneration, pulp capping/dentin regeneration, and bone grafting of large osseous defects in dental and craniofacial reconstruction. Part 1 reviewed the princ...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/1746-160X-2-16
更新日期:2006-05-25 00:00:00
abstract:BACKGROUND:To determine three-dimensional spatial orbit skeletal changes in adolescents over a 19 to 24 months observation period assessed through cone-beam computed tomography (CBCT). METHODS:The sample consisted of 50 adolescents aged 11 to 17. All were orthodontic patients who had two CBCTs taken with an interval o...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/s13005-016-0130-0
更新日期:2016-11-10 00:00:00
abstract:OBJECTIVES:Simultaneous, radiation-free registration of the teeth and the upper and lower jaw positions in relation to the extraoral soft tissue could improve treatment planning and documentation. The purpose of this study is to describe a workflow to solve this form of registration and surface acquisition with a mobil...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/s13005-019-0212-x
更新日期:2019-11-25 00:00:00
abstract:OBJECTIVE:Patients suspected of having swallowing disorders, could highly benefit from simple diagnostic screening before being referred to specialist evaluations. The article analyzes various instrumental methods of dysphagia assessment, introduces surface electromyography (sEMG) to carry out rapid assessment of such ...
journal_title:Head & face medicine
pub_type: 杂志文章,评审
doi:10.1186/1746-160X-5-9
更新日期:2009-02-20 00:00:00
abstract:BACKGROUND:Oral Health-Related Quality of Life (OHRQoL) is an important aspect of quality of life. Acute illnesses, as well as chronic diseases, can have a strong, persisting impact on an individual's quality of life. This study evaluates OHRQoL of patients with odontogenic fascial space abscesses, the underlying condi...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/s13005-019-0201-0
更新日期:2019-06-21 00:00:00
abstract::We describe a case of adenomatoid odontogenic tumor (AOT) associated with odontoma occurring in the posterior mandible of a 32-year-old man. Although calcifications are commonly found in the AOT, the presence of rudimentary dental structures is a very rare phenomenon. Cases with similar aspects have been described as ...
journal_title:Head & face medicine
pub_type: 杂志文章,评审
doi:10.1186/1746-160X-9-20
更新日期:2013-08-09 00:00:00
abstract:INTRODUCTION:The aim of this study was to compare solubility, microhardness, radiopacity, and setting time of Biodentine with ProRoot MTA. METHODS:Solubility in distilled water, radioopacity, and setting time were evaluated in accordance with International Standard ISO 6876:2001. In addition, the solubility in Phospha...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/s13005-015-0074-9
更新日期:2015-05-02 00:00:00
abstract:INTRODUCTION:It has been shown that Low Level Laser (LLL) has a positive effect on bone formation. The aim of this study was to evaluate the effect of low level laser on condylar growth during mandibular advancement in rabbits. MATERIALS AND METHODS:Continuous forward mandibular advancement was performed in fourteen m...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/1746-160X-8-4
更新日期:2012-02-23 00:00:00
abstract:INTRODUCTION:This study determined the amount and severity of EARR (external apical root resorption) after orthodontic treatment with self-ligating (SL) and conventional (Non-SL) brackets. Differences regarding rate of extraction cases, appointments and treatment time were evaluated. MATERIAL AND METHODS:213 patients ...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/1746-160X-10-2
更新日期:2014-01-23 00:00:00
abstract:BACKGROUND:To investigate the prognostic value of a three-dimensional dynamic quantitative analysis system to measure facial motion (3D ASFM) in acute facial palsy patients and compare it with subjective grading methods and electroneurography. METHODS:We continuously recruited 37 patients with acute (< 1 month) Bell's...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/s13005-020-00230-6
更新日期:2020-07-18 00:00:00
abstract:BACKGROUND:CHARGE syndrome (CS) is a rare genetic condition (OMIM #214800). The condition has a variable phenotypic expression. Historically, the diagnosis of CHARGE syndrome was based on the presence of specific clinical criteria. The genetic aetiology of CS has since been elucidated and attributed to pathogenic varia...
journal_title:Head & face medicine
pub_type: 杂志文章,评审
doi:10.1186/s13005-020-00224-4
更新日期:2020-05-08 00:00:00
abstract:OBJECTIVE:To analyze the interradicular trabecular bone density of the lateral maxilla regarding the insertion of temporary anchorage devices (TADs). MATERIAL AND METHODS:The material consisted of tissue blocks of autopsy material from 20 subjects (17 male, 3 female, 16 - 63y). The specimens comprised the dentated alv...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/s13005-015-0058-9
更新日期:2015-02-07 00:00:00
abstract:BACKGROUND:Langerhans cell histiocytosis (LCH), previously known as Histiocytosis X, is an infrequent disease that congregates a wide spectrum of clinical presentations with variable systemic involvement. Unification of these diseases under only one category is based on the almost identical histopathologic features of ...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/s13005-016-0118-9
更新日期:2016-06-02 00:00:00
abstract:INTRODUCTION:The cranial base plays an important role in determining how the mandible and maxilla relate to each other. This study assessed the relationship between the cranial base and jaw base in a Chinese population. METHODS:This study involved 83 subjects (male: 27; female: 56; age: 18.4±4.2 SD years) from Hong Ko...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/1746-160X-10-31
更新日期:2014-08-16 00:00:00
abstract:INTRODUCTION:This study was performed to examine craniofacial structures in persons with hypodontia and to reveal any differences, that may occur, when agenetic teeth are only found in the maxilla, the mandible or in both jaws. The groups consistent of 50 children (33 girls, 17 boys) aged between 9 and 13.5 years were ...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/1746-160X-7-23
更新日期:2011-12-06 00:00:00
abstract:BACKGROUND:Successful treatment of patients with multiple bilateral impactions can be an orthodontic challenge, but few reports on treatment planning and execution exist. CASE PRESENTATION:In this case report, we describe the successful orthodontic treatment of a 16.3-year old female patient without systemic or geneti...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/s13005-016-0122-0
更新日期:2016-07-25 00:00:00
abstract::There is no doubt that the main reason for an internal grauloma is a traumatic event. The trauma may be physical or chemical as in the case of caries or coronal pulpectomy. In most of the cases it is diagnosed by hazard or, when in case of fracture or mobility, extraction is the only therapy to be performed. If diagno...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/s13005-015-0077-6
更新日期:2015-06-12 00:00:00
abstract:BACKGROUND:Recently, medical rapid prototyping (MRP) models, fabricated with computer-aided design and computer-aided manufacture (CAD/CAM) techniques, have been applied to reconstructive surgery in the treatment of head and neck cancers. Here, we tested the use of preoperatively manufactured reconstruction plates, whi...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/1746-160X-10-45
更新日期:2014-10-23 00:00:00
abstract:BACKGROUND:The purpose of this study was to assess the influence of head and neck pathologies on the detection rate, configuration and diameter of the thoracic duct (TD) and right lymphatic duct (RLD) in computed tomography (CT) of the head and neck. METHODS:One hundred ninety-seven patients were divided into the subg...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/s13005-016-0108-y
更新日期:2016-03-31 00:00:00
abstract::The traumatic bone cyst (TBC) is an uncommon nonepithelial lined cavity of the jaws. The lesion is mainly diagnosed in young patients most frequently during the second decade of life. The majority of TBCs are located in the mandibular body between the canine and the third molar. Clinically, the lesion is asymptomatic ...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/1746-160X-2-40
更新日期:2006-11-12 00:00:00
abstract:OBJECTIVES:Primary surgery in patients with complete unilateral and bilateral cleft lip and palate restricts transverse and sagittal maxillary growth. Additional surgical maxillary advancement might become necessary after completion of growth. The aim of this study was to determine the extent of maxillary deficiency at...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/1746-160X-10-26
更新日期:2014-06-20 00:00:00
abstract:BACKGROUND:Ablative tumor surgery often results in continuity defects of the mandible. When an immediate reconstruction using autologous bone grafts is not possible the bridging of the defects with a variety of bridging plates might be achieved. However, those bridging plates have the risk of plate fractures or exposur...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/s13005-016-0114-0
更新日期:2016-04-11 00:00:00
abstract::Ectopic internal carotid artery (ICA) is a very rare variation. The major congenital abnormalities of the ICA can be classified as agenesis, aplasia and hypoplasia, and they can be unilateral or bilateral. Anomalies of the neck artery may be vascular neoplasms or ectopic position. Carotid angiograms provide absolute c...
journal_title:Head & face medicine
pub_type: 杂志文章
doi:10.1186/1746-160X-4-20
更新日期:2008-08-26 00:00:00