Abstract：
PURPOSE:This meta-analysis compared the clinical outcomes of locking plate with intramedullary nail in the treatment of displaced proximal humeral fractures. METHODS:We searched PubMed, Embase, and the Cochrane databases for studies comparing locking plate and intramedullary nail treatment of displaced two-, three-, or four-part proximal humeral fractures. The quality of the studies was assessed, and meta-analysis was performed using the Cochrane Collaboration's REVMAN 5.1 software. RESULTS:A total of 615 patients from eight studies were included in this meta-analysis (348 fractures treated with locking plate and 267 with intramedullary nail). Similar Constant scores were observed between the locking plate and intramedullary nail both in randomized controlled trials (RCTs) (mean difference (MD) = 2.12, 95% confidence interval (CI), -2.54 to 6.79, P = 0.37) and observational studies (MD = -1.93, 95% CI, -4.95 to 1.09, P = 0.21). Only one RCT provided American Shoulder and Elbow Surgeons Standardized scores indicating that the locking plate was better than the intramedullary nail (MD = 7.20, 95% CI, 1.29-13.11, P = 0.02). The total complication rate did not specifically favor the locking plate or intramedullary nail both in the RCTs (risk ratio (RR), 2.44; 95% CI, 0.35-16.78; P = 0.37) and observational studies (RR, 1.01; 95% CI, 0.72-1.43; P = 0.94). CONCLUSIONS:In the existing literature, limited evidence suggests that the locking plate and intramedullary nail are both valuable options for the treatment of proximal humeral fractures. Because of the observed heterogeneity and variance between the subgroups, more RCT are needed to be able to definitively recommend a locking plate or intramedullary nail for specific fracture patterns.
journal_name
J Orthop Surg Resjournal_title
Journal of orthopaedic surgery and researchauthors
Wang G,Mao Z,Zhang L,Zhang L,Zhao Y,Yin P,Gao L,Tang P,Kang Hdoi
10.1186/s13018-015-0242-4subject
Has Abstractpub_date
2015-09-15 00:00:00pages
122issn
1749-799Xpii
10.1186/s13018-015-0242-4journal_volume
10pub_type
杂志文章,meta分析abstract：OBJECTIVE:To discuss the sensitivity and specificity of the combinations of multiple factors that work on bone infection after artificial joint, and provide evidence-based medical basis for the early diagnosis of infection after artificial joint. METHODS:A retrospective review was conducted on 35 patients diagnosed wi...
journal_title：Journal of orthopaedic surgery and research
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journal_title：Journal of orthopaedic surgery and research
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doi：10.1186/s13018-017-0706-9
更新日期：2018-01-05 00:00:00
abstract：PURPOSE:In recent years, there has been an increasing interest in local infiltration analgesia (LIA) as a technique to control postoperative pain. We compared this technique to the gold standard the 3 in 1 femoral nerve block (FNB) in postoperative pain management after total knee arthroplasty (TKA) in a large patient ...
journal_title：Journal of orthopaedic surgery and research
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更新日期：2020-10-19 00:00:00
abstract：BACKGROUND:Posterior transfacet approach has been proved to be a safe and effective access to treat thoracic disc herniation. However, the therapeutic effect and safety of modified transfacet approach for treating thoracic spinal tuberculosis (TST) has not been reported in the clinical literature. In this study, the cl...
journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-018-0994-8
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pub_type： 杂志文章
doi：10.1186/s13018-020-01885-2
更新日期：2020-08-24 00:00:00
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journal_title：Journal of orthopaedic surgery and research
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journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-018-0800-7
更新日期：2018-04-27 00:00:00
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journal_title：Journal of orthopaedic surgery and research
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journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
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journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-020-01771-x
更新日期：2020-07-09 00:00:00
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journal_title：Journal of orthopaedic surgery and research
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更新日期：2019-09-26 00:00:00
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journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-018-0774-5
更新日期：2018-04-03 00:00:00
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doi：10.1186/s13018-018-0857-3
更新日期：2018-06-18 00:00:00
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journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章,已发布勘误
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更新日期：2020-04-30 00:00:00
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journal_title：Journal of orthopaedic surgery and research
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journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/1749-799X-4-17
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journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
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更新日期：2010-10-12 00:00:00
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journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
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更新日期：2015-06-03 00:00:00
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journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-015-0215-7
更新日期：2015-06-12 00:00:00
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journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
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更新日期：2019-11-21 00:00:00
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journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章,评审
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更新日期：2020-08-05 00:00:00
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journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
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更新日期：2019-06-07 00:00:00
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journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
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更新日期：2019-08-08 00:00:00
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journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章,meta分析
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更新日期：2015-01-28 00:00:00
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journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
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更新日期：2020-12-10 00:00:00
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journal_title：Journal of orthopaedic surgery and research
pub_type： 杂志文章
doi：10.1186/s13018-019-1329-0
更新日期：2019-08-28 00:00:00
