Abstract:
BACKGROUND:Site-dependent and interindividual histological differences in Denonvilliers' fascia (DF) are not well understood. This study aimed to examine site-dependent and interindividual differences in DF and to determine whether changes in the current approach to radical prostatectomy are warranted in light of these histological findings. METHODS:Twenty-five donated male cadavers (age range, 72-95 years) were examined. These cadavers had been donated to Sapporo Medical University for research and education on human anatomy. Their use for research was approved by the university ethics committee. Horizontal sections (15 cadavers) or sagittal sections (10 cadavers) were prepared at intervals of 2-5 mm for hematoxylin and eosin staining. Elastic-Masson staining and immunohistochemical staining were also performed, using mouse monoclonal anti-human alpha-smooth muscle actin to stain connective tissues and mouse monoclonal anti-human S100 protein to stain nerves. RESULTS:We observed that DF consisted of disorderly, loose connective tissue and structures resembling "leaves", which were interlacing and adjacent to each other, actually representing elastic or smooth muscle fibers. Variations in DF were observed in the following: 1) configuration of multiple leaves, including clear, unclear, or fragmented behind the body and tips of the seminal vesicles, depending on the site; 2) connection with the lateral pelvic fascia at the posterolateral angle of the prostate posterior to the neurovascular bundles, being clear, unclear, or absent; 3) all or most leaves of DF fused with the prostatic capsule near the base of the seminal vesicles, and periprostatic nerves were embedded in the leaves at the fusion site; and 4) some DF leaves fused with the prostatic capsule anteriorly and/or the fascia propria of the rectum posteriorly. CONCLUSIONS:Site-dependent and interindividual variations in DF were observed in donated elderly male cadavers. All or most DF leaves are fused with the prostatic capsule near the base of the seminal vesicles and some DF leaves are fused with the fascia propria of the rectum posterior. Based on our results, surgeons should be aware of variations and search for them to create a suitable dissection plane to avoid iatrogenic positive margins and rectal injury.
journal_name
BMC Uroljournal_title
BMC urologyauthors
Muraoka K,Hinata N,Morizane S,Honda M,Sejima T,Murakami G,Tewari AK,Takenaka Adoi
10.1186/s12894-015-0034-5subject
Has Abstractpub_date
2015-05-12 00:00:00pages
42issn
1471-2490pii
10.1186/s12894-015-0034-5journal_volume
15pub_type
杂志文章相关文献
BMC Urology文献大全abstract:BACKGROUND:This multicenter, randomized, double-blind, double-dummy, placebo-controlled trial primarily evaluated the efficacy of tadalafil once-daily (OaD) or on-demand ("pro-re-nata"; PRN) treatment, started early post-nsRP. Secondary outcome-measures on quality-of-life (QoL) and treatment satisfaction are reported. ...
journal_title:BMC urology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/s12894-015-0022-9
更新日期:2015-04-12 00:00:00
abstract:BACKGROUND:This study describes and compares health-related quality of life (HRQOL) of prostate cancer patients who received either radical prostatectomy (nerve-sparing, nsRP, or non-nerve-sparing, nnsRP) or radiotherapy (external RT, brachytherapy, or both combined) for treatment of localised prostate cancer. METHODS...
journal_title:BMC urology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12894-015-0025-6
更新日期:2015-04-10 00:00:00
abstract:BACKGROUND:Partial segmental thrombosis of the corpus cavernosum (PSTCC) is a rare disease predominantly occurring in young men. Cardinal symptoms are pain and perineal swelling. Although several risk factors are described in the literature, the exact etiology of penile thrombosis remains unclear in most cases. MRI or ...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-14-100
更新日期:2014-12-17 00:00:00
abstract:BACKGROUND:Cystic renal cell carcinoma (CRCC) is relatively rare; CRCC is frequently misdiagnosed as a benign renal cyst. CRCC carries an excellent prognosis following surgical treatment. The aim of our study was to summarize the management of CRCC and to characterize the prognosis of affected patients. METHODS:A retr...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-14-87
更新日期:2014-11-07 00:00:00
abstract:BACKGROUND:Although there is growing evidence of relationship between obesity and some specific stone compositions, results were inconsistent. Due to a greater relationship between metabolic syndrome and some specific stone type, obesity measured by body mass index (BMI) has limitation in determining relationship betwe...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-015-0013-x
更新日期:2015-03-14 00:00:00
abstract:BACKGROUND:In patients with neurogenic bladder (NB), elevated intravesical pressures can be transmitted to the upper urinary tract, causing hydronephrosis (HN) and ureteral dilation (UD), which are referred to as upper urinary tract dilation (UUTD). Ureteral obstruction at the bladder wall is another cause for UUTD, bu...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-14-38
更新日期:2014-05-22 00:00:00
abstract:BACKGROUND:Urinary incontinence (UI) is highly prevalent and affects the lives of many men and women. We aimed to conduct a qualitative evidence synthesis (QES) to explore the experience of living with UI and to develop a conceptual model that can help us to understand this experience, and the potential barriers to app...
journal_title:BMC urology
pub_type: 杂志文章,meta分析
doi:10.1186/s12894-019-0555-4
更新日期:2020-01-16 00:00:00
abstract:BACKGROUND:Nutcracker syndrome is an entity resulting from left renal vein compression by the aorta and the superior mesenteric artery, which leads to symptoms of hematuria or left flank pain. The alternative option of endovascular or extravascular stenting is very appealing because of the minimal invasive procedures. ...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-015-0063-0
更新日期:2015-07-24 00:00:00
abstract:BACKGROUND:To establish and internally validate an innovative R.I.R.S. scoring system that allows urologists to preoperatively estimate the stone-free rate (SFR) after retrograde intrarenal surgery (RIRS). METHODS:This study included 382 eligible samples from a total 573 patients who underwent RIRS from January 2014 t...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-017-0297-0
更新日期:2017-11-21 00:00:00
abstract:BACKGROUND:Wilms tumor is the most common renal tumor of childhood. Duplication of the inferior vena cava is an uncommon anomaly. In the present study, we present a case of Wilms tumor with the inferior vena cava duplication, which has not been reported previously. CASE PRESENTATION:A 14-month-old female presented wit...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-018-0401-0
更新日期:2018-10-19 00:00:00
abstract:BACKGROUND:This very large population-based study investigated outcomes after a diagnosis of prostate cancer (PCa) in terms of mortality rates, treatments and adverse effects. METHODS:Among the 11 million men aged 40 years and over covered by the general national health insurance scheme, those with newly managed PCa i...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-14-48
更新日期:2014-06-13 00:00:00
abstract:BACKGROUND:Polyorchidism is a congenital anomaly of the urogenital system and means more than two testes. It is a rare phenomenon, where there are no more than 200 reported cases in the literature. In this case, we report a 13-month year's old case with five testicles. CASE PRESENTATION:We report a rare five testicles...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-020-00681-8
更新日期:2020-08-20 00:00:00
abstract:BACKGROUND:To investigate the feasibility and safety of surgical treatment for Peyronie's disease (PD) by excising and repairing plaque using autologous tunica vaginalis of testis. METHODS:From March 2007 to December 2012, total 19 patients with PD underwent surgical treatment at our center. All patients had significa...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-016-0120-3
更新日期:2016-01-13 00:00:00
abstract:BACKGROUND:The presence of lymph nodes (LN) within the prostatic anterior fat pad (PAFP) has been reported in several recent reports. These PAFP LNs rarely harbor metastatic disease, and the characteristics of patients with PAFP LN metastasis are not well-described in the literature. Our previous study suggested that m...
journal_title:BMC urology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12894-015-0070-1
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is a rare hereditary kidney cancer syndrome in which affected individuals are at risk of skin and uterine leiomyomatosis and kidney cancer. HLRCC-associated kidney cancer is a lethal disease with a highly aggressive behavior, and there is no standard...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-019-0484-2
更新日期:2019-06-10 00:00:00
abstract:BACKGROUND:Sacral neuromodulation operations have usually been performed based on 2D fluoro images. However, sacral nerve stimulation lead implantation may be challenging when the normal anatomy is confused by obesity or congenital anomalies. Thus the surgical navigation and intraoperative imaging methods could be help...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-13-48
更新日期:2013-10-16 00:00:00
abstract:BACKGROUND:Adult men with autoimmune conditions are commonly prescribed anti-tumor necrosis factor (anti-TNF) agents; however, there is a paucity of quality evidence as to their effect on male fertility (e.g. semen parameters and sperm quality). Our objective was to determine if men with autoimmune conditions are being...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-020-00658-7
更新日期:2020-07-27 00:00:00
abstract:BACKGROUND:The objective of this study was to describe overall survival and the management of men with favorable risk prostate cancer (PCa) within a large community-based health care system in the United States. METHODS:A retrospective cohort study was conducted using linked electronic health records from men aged ≥40...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-018-0372-1
更新日期:2018-06-04 00:00:00
abstract:BACKGROUND:Kidney cancer is a lethal neoplasm that affects several thousands of people every year. Renal cell carcinoma (RCC) is the most common histologic type. Recent developments in the therapeutic approach include antiangiogenic targeted approaches and Immunotherapy. Thus, the therapeutic algorithm of RCC patients ...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-020-00618-1
更新日期:2020-06-02 00:00:00
abstract:BACKGROUND:The use of ureteral access sheath (UAS) during ureteroscopy is controversial. We aimed to explore practice patterns of UAS during ureteroscopy for nephrolithiasis among endourologists worldwide. METHODS:A 15-question survey was designed using the SurveyMonkey® platform. The questions covered the background ...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-019-0489-x
更新日期:2019-07-04 00:00:00
abstract:BACKGROUND:Prostate cancer is the most frequently reported cancer in males in Europe, and is associated with substantial morbidity and mortality. The aim of the current review was to characterize the clinical, economic and humanistic burden of disease associated with prostate cancer in France, Germany, the UK and Canad...
journal_title:BMC urology
pub_type: 杂志文章,评审
doi:10.1186/s12894-019-0448-6
更新日期:2019-03-18 00:00:00
abstract::This review summarizes recent literature on advances regarding renal and ureteral calculi, with particular focus in areas of recent advances in the overall field of urolithiasis. Clinical management in everyday practice requires a complete understanding of the issues regarding metabolic evaluation and subgrouping of s...
journal_title:BMC urology
pub_type: 杂志文章,评审
doi:10.1186/1471-2490-13-10
更新日期:2013-02-16 00:00:00
abstract:BACKGROUND:Previous studies have suggested a greater benefit for various outcomes in men diagnosed with benign prostatic hyperplasia (BPH) who are treated with dutasteride than for men treated with finasteride. This study investigates whether the rates of BPH-related prostate surgery and acute urinary retention (AUR) d...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-016-0170-6
更新日期:2016-08-31 00:00:00
abstract:BACKGROUND:PSA-directed prostate cancer screening leads to a high rate of false positive identifications and an unnecessary biopsy burden. Epigenetic biomarkers have proven useful, exhibiting frequent and abundant inactivation of tumor suppressor genes through such mechanisms. An epigenetic, multiplex PCR test for pros...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-12-16
更新日期:2012-06-06 00:00:00
abstract:BACKGROUND:The purpose of this study was to explore the budget impact of dutasteride plus tamsulosin fixed-dose combination (DUT + TAM FDC) versus tamsulosin monotherapy, in the treatment of patients with benign prostatic hyperplasia (BPH) from the perspective of the Greek healthcare insurance system. METHODS:A Micros...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-14-78
更新日期:2014-09-26 00:00:00
abstract:BACKGROUND:Extracorporeal shockwave lithotripsy (ESWL) is the management of choice for renal stones 20 mm or smaller, with a stone clearance rate of up to 89%. The purpose of the present is to investigate the efficacy of a commercialised ESWL service, being performed as an outsourced treatment using a mobile lithotrips...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-017-0249-8
更新日期:2017-07-27 00:00:00
abstract:BACKGROUND:The current research aims to evaluate the risk factors of urethrocutaneous fistula after hypospadias surgery among the youth in China. METHODS:One hundred twenty hypospadias patients were enrolled in our study. All of them were defined as Tanner 4 or 5. The information collected from the participants includ...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-018-0366-z
更新日期:2018-07-24 00:00:00
abstract:BACKGROUND:The aim was to retrospectively assess the results of treatment of upper urinary tract stones with the Sonolith vision manufactured by EDAP, and purchased in 2004. METHODS:The subjects were 226 Japanese patients who underwent extracorporeal shock wave lithotripsy (ESWL) alone as an initial treatment and coul...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-11-26
更新日期:2011-12-12 00:00:00
abstract:BACKGROUND:It is well recognized that the presence of positive surgical margins (PSM) after radical prostatectomy (RP) adversely affects cancer specific outcomes and recent evidence from randomized trials supports the use of adjuvant radiotherapy in these cases. However, not all of the patients with PSM develop disease...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-14-79
更新日期:2014-10-02 00:00:00
abstract:BACKGROUND:To evaluate the role of free-hand transperineal targeted prostate biopsy using multiparametric magnetic resonance imaging-transrectal ultrasound (mpMRI-TRUS) fusion in Chinese men with repeated biopsy. METHODS:A total of 101 consecutive patients suspicious of prostate cancer (PCa) at the mpMRI scan and with...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-017-0241-3
更新日期:2017-07-05 00:00:00