The effect of isoniazid preventive therapy on incidence of tuberculosis among HIV-infected clients under pre-ART care, Jimma, Ethiopia: a retrospective cohort study.

Abstract:

BACKGROUND:Tuberculosis (TB) is a major public health problem that accounts for almost half a million human immunodeficiency virus (HIV) associated deaths. Provision of isoniazid preventive therapy (IPT) is one of the public health interventions for the prevention of TB in HIV infected individuals. However, in Ethiopia, the coverage and implementation of IPT is limited. The objective of this study is to compare the incidence rate of TB, TB-free survival time and identify factors associated with development TB among HIV-infected individuals on pre-ART follow up. METHODS:A retrospective cohort study was conducted from January, 2008 to February 31, 2012 in Jimma hospital. Kaplan-Meier survival plots were used to calculate the crude effect in both groups on TB-free survival probabilities and compared using the log rank test. A Cox proportional hazard model was used to identify predictors of TB. RESULT:A total of 588 patients on pre-ART care (294 IPT and 294 non-IPT group) were followed retrospectively for a median duration of 24.1 months. The median CD4 (+) cell count was 422 cells/μl (IQR 344-589). During the follow up period, 49 individuals were diagnosed with tuberculosis, giving an overall incidence of 3.78 cases per 100 person year (PY). The incidence rate of TB was 5.06 per 100 PY in non-IPT group and 2.22 per 100 PY in IPT user group. Predictors of higher TB risk were: being on clinical WHO stage III/IV (adjusted hazard ratio (AHR = 3.05, 95% confidence interval (CI): 1.61, 5.81); non-IPT user (AHR = 2.02, 95% CI: 1.04, 3.92); having CD4 (+) cell count less than 350 cells/μl (AHR = 3.16, 95% CI: 1.04, 3.92) and between 350-499 cells/μl, (AHR = 2.87; 95% CI: 1.37-6.03) and having episode of opportunistic infection (OI) in the past (AHR = 2.41, 95% CI: 1.33-4.34). CONCLUSION:IPT use was associated with fifty percent reduction in new cases of tuberculosis and probability of developing TB was higher in non-IPT group. Implementing the widespread use of IPT has the potential to reduce TB rates substantially among HIV-infected individuals in addition to other tuberculosis prevention and control effort in resource limited settings.

journal_name

BMC Public Health

journal_title

BMC public health

authors

Assebe LF,Reda HL,Wubeneh AD,Lerebo WT,Lambert SM

doi

10.1186/s12889-015-1719-0

subject

Has Abstract

pub_date

2015-04-10 00:00:00

pages

346

issn

1471-2458

pii

10.1186/s12889-015-1719-0

journal_volume

15

pub_type

杂志文章
  • Association of vitamin D status with socio-demographic factors in Calgary, Alberta: an ecological study using Census Canada data.

    abstract:BACKGROUND:Low 25-hydroxyvitamin D levels are a global health problem with northern countries such as Canada at particular risk. A number of sociodemographic factors have been reported to be associated with low vitamin D levels but prior studies have been limited by the ability of the researchers to gather this data di...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/1471-2458-13-316

    authors: Naugler C,Zhang J,Henne D,Woods P,Hemmelgarn BR

    更新日期:2013-04-08 00:00:00

  • Skin antiseptics in healthcare facilities: is a targeted approach necessary?

    abstract:BACKGROUND:Skin antisepsis occurs in every healthcare environment. From basic hand hygiene, to antiseptic bathing and pre surgical care with alcohol/chlorhexidine, use of antimicrobial agents to reduce the skin microflora has skyrocketed in the past several years. Although used in hopes of reducing the likelihood of in...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/s12889-019-7507-5

    authors: Wiemken TL

    更新日期:2019-08-22 00:00:00

  • Identification of food insecurity factors in French-speaking Belgium: a qualitative study.

    abstract:BACKGROUND:Diet is an essential determinant of health. Among the health determinants, we find access problems that are summarized as food insecurity. While such food insecurity has been studied in other countries and correlated to several health problems, it has been scarcely assessed in Belgium. The purpose of this wo...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/s12889-019-7860-4

    authors: Huberland V,Semaille P,Kacenelenbogen N

    更新日期:2019-12-05 00:00:00

  • The social determinants of otitis media in aboriginal children in Australia: are we addressing the primary causes? A systematic content review.

    abstract:BACKGROUND:Aboriginal and Torres Strait Islander children experience some of the highest rates of otitis media in the world. Key risk factors for otitis media in Aboriginal children in Australia are largely social and environmental factors such as overcrowded housing, poverty and limited access to services. Despite thi...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/s12889-020-08570-3

    authors: DeLacy J,Dune T,Macdonald JJ

    更新日期:2020-04-15 00:00:00

  • A registry-based follow-up study, comparing the incidence of cardiovascular disease in native Danes and immigrants born in Turkey, Pakistan and the former Yugoslavia: do social inequalities play a role?

    abstract:BACKGROUND:This study compared the incidence of cardiovascular disease (CVD) and acute myocardial infarction (AMI) between native Danes and immigrants born in Turkey, Pakistan and the former Yugoslavia. Furthermore, we examined whether different indicators of socioeconomic status (SES), such as employment, income and h...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/1471-2458-11-662

    authors: Hempler NF,Larsen FB,Nielsen SS,Diderichsen F,Andreasen AH,Jørgensen T

    更新日期:2011-08-23 00:00:00

  • Cultural activity participation and associations with self-perceived health, life-satisfaction and mental health: the Young HUNT Study, Norway.

    abstract:BACKGROUND:Leisure time activities and culture participation may have health effects and be important in pulic health promotion. More knowledge on how cultural activity participation may influence self-perceived health, life-satisfaction, self-esteem and mental health is needed. METHODS:This article use data from the ...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/s12889-015-1873-4

    authors: Hansen E,Sund E,Skjei Knudtsen M,Krokstad S,Holmen TL

    更新日期:2015-06-10 00:00:00

  • The effectiveness of "Exercise on Prescription" in stimulating physical activity among women in ethnic minority groups in the Netherlands: protocol for a randomized controlled trial.

    abstract:BACKGROUND:Lack of physical activity is an important risk factor for overweight, diabetes, cardiovascular disease and other chronic conditions. In the Netherlands, ethnic minority groups are generally less physically active and rate their own health poorer compared to ethnic Dutch. This applies in particular to women. ...

    journal_title:BMC public health

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2458-8-406

    authors: Hosper K,Deutekom M,Stronks K

    更新日期:2008-12-10 00:00:00

  • Provincial alcohol index and its relationship to alcohol-related harm in Thailand: implications for subnational alcohol policy development.

    abstract:BACKGROUND:The Provincial Alcohol Index (PAI) is one of the efforts to develop a composite measurement to operationalize the situation of alcohol consumption and related risk behaviors. The index offers a means for national and subnational alcohol control committees to address alcohol-related problems in their responsi...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/s12889-016-3217-4

    authors: Chaiyasong S,Thamarangsi T

    更新日期:2016-07-11 00:00:00

  • Sanitation behavior among schoolchildren in a multi-ethnic area of Northern rural Vietnam.

    abstract:BACKGROUND:In Vietnam, efforts are underway to improve latrine use in rural and remote areas with particular focus on increasing coverage of sanitation in schools. However, there is a lack of information on how the school program affects latrine use by schoolchildren and at community level. This paper analyzes sanitati...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/1471-2458-12-140

    authors: Le TT,Luu NH,Rheinländer T,Dalsgaard A,Konradsen F

    更新日期:2012-02-21 00:00:00

  • Healthy eating and obesity prevention for preschoolers: a randomised controlled trial.

    abstract:BACKGROUND:Developing effective prevention and intervention programs for the formative preschool years is seen as an essential step in combating the obesity epidemic across the lifespan. The overall goal of the current project is to measure the effectiveness of a healthy eating and childhood obesity prevention interven...

    journal_title:BMC public health

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2458-10-220

    authors: Skouteris H,McCabe M,Swinburn B,Hill B

    更新日期:2010-04-28 00:00:00

  • Temporal changes in the prevalence of childhood asthma and allergies in urban and rural areas of Cyprus: results from two cross sectional studies.

    abstract:BACKGROUND:The prevalence of childhood asthma and allergies in Cyprus was significantly higher in urban compared to rural areas back in the year 2000, against a background of an overall low prevalence (e.g. current wheeze 6.9%) by comparison to northern European countries. In this study we aimed to assess temporal chan...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/1471-2458-11-858

    authors: Kolokotroni O,Middleton N,Nicolaou N,Pipis S,Priftis KN,Milton DK,Yiallouros PK

    更新日期:2011-11-11 00:00:00

  • Prevalence of latent tuberculosis infection among coal workers' pneumoconiosis patients in China: a cross-sectional study.

    abstract:BACKGROUND:Little is known about the prevalence of latent tuberculosis infection (LTBI) among coal workers' pneumoconiosis (CWP) patients. To estimate the prevalence of LTBI and identify its associated risk factors among CWP patients. METHODS:A cross-sectional study was conducted to assess the prevalence of LTBI. Part...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/s12889-018-5373-1

    authors: Jin Y,Wang H,Zhang J,Ding C,Wen K,Fan J,Li T

    更新日期:2018-04-11 00:00:00

  • Non-adherence to anti-retroviral therapy among HIV infected adults in Mon State of Myanmar.

    abstract:BACKGROUND:The provision of Anti-Retroviral Therapy (ART) was started in Myanmar in 2005 in collaboration with the National AIDS Program and the private sector. Successful clinical management of HIV-infected patients is subject to optimal adherence. The aim of the study was to determine the prevalence of adherence to A...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/s12889-017-4309-5

    authors: Aye WL,Puckpinyo A,Peltzer K

    更新日期:2017-05-05 00:00:00

  • Psychosocial factors associated with becoming a young father in Finland: a nationwide longitudinal study.

    abstract:BACKGROUND:Little is known about the characteristics of boys who become fathers at young age. Some studies have suggested that antisocial adolescents are more likely to be young fathers. The aim of this study was to examine the associations of psychosocial factors in childhood with becoming a young father, and to asses...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/1471-2458-12-560

    authors: Lehti V,Sourander A,Sillanmäki L,Helenius H,Tamminen T,Kumpulainen K,Almqvist F

    更新日期:2012-07-27 00:00:00

  • Low HIV viral suppression rates following the intensive adherence counseling (IAC) program for children and adolescents with viral failure in public health facilities in Uganda.

    abstract:BACKGROUND:The UNAIDS 90-90-90 strategy clearly stipulates that 90% of all people on antiretroviral therapy (ART) should have a suppressed viral load. Intensified adherence counselling (IAC) was recently recommended by WHO to improve viral suppression among ART-treated paediatric and adolescent clients with virological...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/s12889-018-5964-x

    authors: Nasuuna E,Kigozi J,Babirye L,Muganzi A,Sewankambo NK,Nakanjako D

    更新日期:2018-08-22 00:00:00

  • Weight status and hypertension among adolescent girls in Argentina and Norway: data from the ENNyS and HUNT studies.

    abstract:BACKGROUND:To provide data on overweight, obesity and hypertension among adolescent girls in Norway and Argentina. METHODS:Data was obtained from two population-based, cross-sectional and descriptive studies containing anthropometric and blood pressure measurements of 15 to 18 year old girls. The study included 2,156 ...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/1471-2458-9-398

    authors: Stray-Pedersen M,Helsing RM,Gibbons L,Cormick G,Holmen TL,Vik T,Belizán JM

    更新日期:2009-10-30 00:00:00

  • Gender differences in alcohol-related non-consensual sex; cross-sectional analysis of a student population.

    abstract:BACKGROUND:Sexual offences are a global public health concern. Recent changes in the law in England and Wales have dramatically altered the legal landscape of sexual offences, but sexual assaults where the victim is voluntarily intoxicated by alcohol continue to have low conviction rates. Worldwide, students are high c...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/1471-2458-12-216

    authors: Gunby C,Carline A,Bellis MA,Beynon C

    更新日期:2012-03-20 00:00:00

  • Seasonality in diabetes in Yaounde, Cameroon: a relation with precipitation and temperature.

    abstract:BACKGROUND:Diabetes is a growing health concern in developing countries, with Cameroon population having an estimated 6% affected. Of note, hospital attendees appear to be increasing all over the country, with fluctuating numbers throughout the annual calendar. The aim of the study was to investigate the relationship b...

    journal_title:BMC public health

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12889-016-3090-1

    authors: Lontchi-Yimagou E,Tsalefac M,Tapinmene LM,Noubiap JJ,Balti EV,Nguewa JL,Dehayem M,Sobngwi E

    更新日期:2016-06-06 00:00:00

  • The lifelong socioeconomic disadvantage of single-mother background - the Helsinki Birth Cohort study 1934-1944.

    abstract:BACKGROUND:Growing up with one parent is associated with economic hardship and health disadvantages, but there is limited evidence of its lifetime consequences. We examined whether being born to an unmarried mother is associated with socioeconomic position and marital history over the lifespan. METHODS:We analysed dat...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/s12889-016-3485-z

    authors: Mikkonen HM,Salonen MK,Häkkinen A,Olkkola M,Pesonen AK,Räikkönen K,Osmond C,Eriksson JG,Kajantie E

    更新日期:2016-08-18 00:00:00

  • Evaluating the performance of interpreting Verbal Autopsy 3.2 model for establishing pulmonary tuberculosis as a cause of death in Ethiopia: a population-based cross-sectional study.

    abstract:BACKGROUND:In resource- poor settings, verbal autopsy data are often reviewed by physicians in order to assign the probable cause of death. But in addition to being time and energy consuming, the method is liable to produce inconsistent results. The aim of this study is to evaluate the performance of the InterVA 3.2 mo...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/1471-2458-12-1039

    authors: Tadesse S,Tadesse T

    更新日期:2012-11-29 00:00:00

  • A systematic review of economic evaluations of interventions to tackle cardiovascular disease in low- and middle-income countries.

    abstract:BACKGROUND:Low-and middle-income countries are facing both a mounting burden of cardiovascular disease (CVD) as well as severe resource constraints that keep them from emulating some of the extensive strategies pursued in high-income countries. There is thus an urgency to identify and implement those interventions that...

    journal_title:BMC public health

    pub_type: 杂志文章,评审

    doi:10.1186/1471-2458-12-2

    authors: Suhrcke M,Boluarte TA,Niessen L

    更新日期:2012-01-03 00:00:00

  • A systematic review of the clinical and social epidemiological research among sex workers in Uganda.

    abstract:BACKGROUND:In response to the high burden of disease among sex workers and their position as a population heavily affected by the HIV epidemic, there has been a growing body of literature investigating the prevalence and risk factors associated with HIV risk among sex workers. To contextualize and summarize the existin...

    journal_title:BMC public health

    pub_type: 杂志文章,meta分析,评审

    doi:10.1186/s12889-015-2553-0

    authors: Muldoon KA

    更新日期:2015-12-09 00:00:00

  • Dietary patterns and risk of colorectal cancer in Tehran Province: a case-control study.

    abstract:BACKGROUND:Colorectal cancer is the third and fourth leading cause of cancer incidence and mortality among men and women, respectively in Iran. However, the role of dietary factors that could contribute to this high cancer incidence remains unclear. The aim of this study was to determine major dietary patterns and its ...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/1471-2458-13-222

    authors: Safari A,Shariff ZM,Kandiah M,Rashidkhani B,Fereidooni F

    更新日期:2013-03-12 00:00:00

  • Factors affecting early identification of pregnant women by community health workers in Morogoro, Tanzania.

    abstract:BACKGROUND:It is recommended that Antenatal Care (ANC) be initiated within the first trimester of pregnancy for essential interventions, such folic acid supplementation, to be effective. In Tanzania, only 24% of mothers attend their first ANC appointment during their first trimester. Studies have shown that women who h...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/s12889-019-7179-1

    authors: Frumence G,Goodman M,Chebet JJ,Mosha I,Bishanga D,Chitama D,Winch PJ,Killewo J,Baqui AH

    更新日期:2019-07-08 00:00:00

  • Personal ultraviolet Radiation exposure in a cohort of Chinese mother and child pairs: the Chinese families and children study.

    abstract:BACKGROUND:Few studies in China have examined personal ultraviolet radiation (UVR) exposure using polysulfone dosimetry. METHODS:In this study, 93 mother and adolescent child pairs (N = 186) from two locations in China, one rural (higher latitude) and one urban (lower latitude), completed 3 days of personal UVR dosime...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/s12889-019-6610-y

    authors: Kimlin MG,Fang L,Feng Y,Wang L,Hao L,Fan J,Wang N,Meng F,Yang R,Cong S,Liang X,Wang B,Linet M,Potischman N,Kitahara C,Chao A,Wang Y,Sun J,Brodie A

    更新日期:2019-03-08 00:00:00

  • The cost of acute respiratory infections in Northern India: a multi-site study.

    abstract:BACKGROUND:Despite the high mortality and morbidity resulting from acute respiratory infections (ARI) globally, there are few data from low-income countries on costs of ARI to inform public health policy decisions We conducted a prospective survey to assess costs of ARI episodes in selected primary, secondary, and tert...

    journal_title:BMC public health

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12889-015-1685-6

    authors: Peasah SK,Purakayastha DR,Koul PA,Dawood FS,Saha S,Amarchand R,Broor S,Rastogi V,Assad R,Kaul KA,Widdowson MA,Lal RB,Krishnan A

    更新日期:2015-04-07 00:00:00

  • The impact of education programs on smoking prevention: a randomized controlled trial among 11 to 14 year olds in Aceh, Indonesia.

    abstract:BACKGROUND:School-based smoking prevention programs have been shown to increase knowledge of the negative effects of smoking and prevent tobacco smoking. The majority of evidence on effectiveness comes from Western countries. This study investigated the impact of school-based smoking prevention programs on adolescents'...

    journal_title:BMC public health

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2458-13-367

    authors: Tahlil T,Woodman RJ,Coveney J,Ward PR

    更新日期:2013-04-19 00:00:00

  • The Sydney Diabetes Prevention Program: a community-based translational study.

    abstract:BACKGROUND:Type 2 diabetes is a major public health problem in Australia with prevalence increasing in parallel with increasing obesity. Prevention is an essential component of strategies to reduce the diabetes burden. There is strong and consistent evidence from randomised controlled trials that type 2 diabetes can be...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/1471-2458-10-328

    authors: Colagiuri S,Vita P,Cardona-Morrell M,Singh MF,Farrell L,Milat A,Haas M,Bauman A

    更新日期:2010-06-10 00:00:00

  • A qualitative study of the anticipated barriers and facilitators to the implementation of a lifestyle intervention in the Dutch construction industry.

    abstract:BACKGROUND:Lifestyle interventions have proven effective for lowering a cardiovascular risk profile by improving lifestyle behaviors, blood glucose and blood cholesterol levels. However, implementation of lifestyle interventions is often met with barriers. This qualitative study sought to determine anticipated barriers...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/1471-2458-14-1317

    authors: Tonnon SC,Proper KI,van der Ploeg HP,Westerman MJ,Sijbesma E,van der Beek AJ

    更新日期:2014-12-23 00:00:00

  • Low usage of government healthcare facilities for acute respiratory infections in guatemala: implications for influenza surveillance.

    abstract:BACKGROUND:Sentinel surveillance for severe acute respiratory infections in hospitals and influenza-like illness in ambulatory clinics is recommended to assist in global pandemic influenza preparedness. Healthcare utilization patterns will affect the generalizability of data from sentinel sites and the potential to use...

    journal_title:BMC public health

    pub_type: 杂志文章

    doi:10.1186/1471-2458-11-885

    authors: Lindblade KA,Johnson AJ,Arvelo W,Zhang X,Jordan HT,Reyes L,Fry AM,Padilla N

    更新日期:2011-11-24 00:00:00