Common carotid artery intima-media thickness is useful for diagnosis of the acute stage of Kawasaki disease.

Abstract:

BACKGROUND:This study aimed to investigate intima-media thickness (IMT) of the common carotid arteries in children with acute Kawasaki disease (KD). METHODS:Between 2009 and 2011, patients fulfilling the criteria for KD, including a fever lasting >5 days, were prospectively enrolled in this study. Laboratory data, echocardiography, and IMT were measured and compared with matched controls. RESULTS:A total of 70 common carotid IMTs were measured in 35 children. We studied 21 patients aged 3-60 months old with acute KD and 14 febrile patients aged 3-194 months old with acute infection and similar characteristics to those of KD patients. Children with KD had a significantly higher IMT compared with the controls (0.550 ± 0.081 mm vs. 0.483 ± 0.046 mm, P = 0.01). CONCLUSIONS:IMT during the acute stage of KD is increased, suggesting that IMT could be a useful diagnostic tool in the early diagnosis of KD.

journal_name

BMC Pediatr

journal_title

BMC pediatrics

authors

Wu TH,Kuo HC,Tain YL,Lin KM,Kuo HC,Chien SJ

doi

10.1186/1471-2431-14-98

subject

Has Abstract

pub_date

2014-04-10 00:00:00

pages

98

issn

1471-2431

pii

1471-2431-14-98

journal_volume

14

pub_type

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