Abstract:
BACKGROUND:This study aimed to investigate intima-media thickness (IMT) of the common carotid arteries in children with acute Kawasaki disease (KD). METHODS:Between 2009 and 2011, patients fulfilling the criteria for KD, including a fever lasting >5 days, were prospectively enrolled in this study. Laboratory data, echocardiography, and IMT were measured and compared with matched controls. RESULTS:A total of 70 common carotid IMTs were measured in 35 children. We studied 21 patients aged 3-60 months old with acute KD and 14 febrile patients aged 3-194 months old with acute infection and similar characteristics to those of KD patients. Children with KD had a significantly higher IMT compared with the controls (0.550 ± 0.081 mm vs. 0.483 ± 0.046 mm, P = 0.01). CONCLUSIONS:IMT during the acute stage of KD is increased, suggesting that IMT could be a useful diagnostic tool in the early diagnosis of KD.
journal_name
BMC Pediatrjournal_title
BMC pediatricsauthors
Wu TH,Kuo HC,Tain YL,Lin KM,Kuo HC,Chien SJdoi
10.1186/1471-2431-14-98subject
Has Abstractpub_date
2014-04-10 00:00:00pages
98issn
1471-2431pii
1471-2431-14-98journal_volume
14pub_type
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