Abstract:
BACKGROUND:Sero-positivity rates of the rubella virus among pregnant women vary widely throughout the world. In Tanzania, rubella vaccination is not included in the national immunization schedule and there is therefore no antenatal screening for this viral disease. So far, there are no reports on the sero-prevalence of rubella among pregnant women in Tanzania. As a result, this study was undertaken to establish the sero-positivity rate of rubella and rubella risk factors among pregnant women attending antenatal care clinics in Mwanza, Tanzania. METHODS:From November 2012 to May 2013 a total of 350 pregnant women were enrolled and their serum samples collected and analyzed using the AXSYM anti-rubella virus IgG/IgM-MEIA test. Demographic and clinical data were collected using a standardized data collection tool. Data analysis was done using STATA version 12. RESULTS:Of 342 pregnant women tested for rubella antibodies, 317 (92.6%) were positive for anti-rubella IgG while only 1 (0.3%) was positive for IgM. Higher sero-positivity rates were found in the age group of 25-44 years. Furthermore, it was observed that with each year increase in age, the risk of contracting rubella increases by 12% (OR = 1.12, 95% CI: 1.02-1.22, P = 0.019). Women involved in farming and business women were at a higher risk of contracting rubella infection compared to formally employed women (OR: 4.9, P = 0.011; OR 7.1, p = 0.003 respectively). In univariate analysis, the risk of contracting rubella virus infection was found to increase with gestational age with a statistical significance. CONCLUSIONS:Sero-positivity rates of rubella are high in Mwanza and are significantly associated with an increase in age and being a farmer or a business woman. Screening of rubella and immunization of women at risk are highly recommended in this area with a high non-immune rate against rubella virus.
journal_name
BMC Pregnancy Childbirthjournal_title
BMC pregnancy and childbirthauthors
Mwambe B,Mirambo MM,Mshana SE,Massinde AN,Kidenya BR,Michael D,Morona D,Majinge C,Groß Udoi
10.1186/1471-2393-14-95subject
Has Abstractpub_date
2014-03-03 00:00:00pages
95issn
1471-2393pii
1471-2393-14-95journal_volume
14pub_type
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journal_title:BMC pregnancy and childbirth
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abstract::An amendment to this paper has been published and can be accessed via the original article. ...
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pub_type: 杂志文章,已发布勘误
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更新日期:2009-12-18 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2020-05-06 00:00:00
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journal_title:BMC pregnancy and childbirth
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更新日期:2014-12-19 00:00:00
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更新日期:2015-09-07 00:00:00
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pub_type: 杂志文章
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更新日期:2017-06-29 00:00:00