Abstract:
BACKGROUND:The strongest risk factor for depression is having a family history of the condition. Many individuals with a family history of depression are concerned about their personal risk for depression and report unmet educational and psychological support needs. No supportive and/or educational interventions are currently available that target this group of individuals. In this study we will develop and evaluate the first online psycho-educational intervention targeted to individuals with a family history of depression. Genetic risk information and evidence-rated information on preventive strategies for depression will be provided to such individuals in a general practice setting. The intervention will also incorporate a risk assessment tool. The content and delivery of the intervention will be pilot-tested. METHODS/DESIGN:The proposed intervention will be evaluated in the general practitioner (GPs) setting, using a cluster randomized controlled trial. GP practices will be randomized to provide either access to the online, targeted psycho-educational intervention or brief generic information about depression (control) to eligible patients. Eligibility criteria include having at least one first-degree relative with either major depressive disorder (MDD) or bipolar disorder (BD). The primary outcome measure is 'intention to adopt, or actual adoption of, risk-reducing strategies'. Secondary outcome measures include: depression symptoms, perceived stigma of depression, knowledge of risk factors for development of depression and risk-reducing strategies, and perceived risk of developing depression or having a recurrence of family history. Over the course of the study, participants will complete online questionnaires at three time points: at baseline, and two weeks and six months after receiving the intervention or control condition. DISCUSSION:This novel psycho-educational intervention will provide individuals with a family history of depression with information on evidence-based strategies for the prevention of depression, thus, we hypothesize, enabling them to make appropriate lifestyle choices and implement behaviors designed to reduce their risk for depression. The online psycho-educational intervention will also provide a model for similar interventions aimed at individuals at increased familial risk for other psychiatric disorders. TRIAL REGISTRATION:The study is registered with the Australian and New Zealand Clinical Trials Group (Registration no: ACTRN12613000402741).
journal_name
BMC Psychiatryjournal_title
BMC psychiatryauthors
Meiser B,Schofield PR,Trevena L,Wilde A,Barlow-Stewart K,Proudfoot J,Peate M,Dobbins T,Christensen H,Sherman KA,Karatas J,Mitchell PBdoi
10.1186/1471-244X-13-325subject
Has Abstractpub_date
2013-12-01 00:00:00pages
325issn
1471-244Xpii
1471-244X-13-325journal_volume
13pub_type
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