Abstract:
:The blockade of the PD-1 pathway can increase the production of interferon γ by tumor-specific T cells located within or in the proximity of the malignant lesion, thereby increasing the chemokine-dependent trafficking of immune effector cells. This can boost the efficacy of adoptive T-cell therapy to achieve superior antitumor responses.
journal_name
Oncoimmunologyjournal_title
Oncoimmunologyauthors
Peng W,Lizée G,Hwu Pdoi
10.4161/onci.22691subject
Has Abstractpub_date
2013-02-01 00:00:00pages
e22691issue
2eissn
2162-4011issn
2162-402Xpii
2012ONCOIMM0341journal_volume
2pub_type
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