Abstract:
:Near-infrared (NIR) emitting probes with very large Stokes' shifts play a crucial role in bioimaging applications, as the optical signals in this region exhibit high signal to background ratio and allow deeper tissue penetration. Herein we illustrate NIR-emitting probe 2 with very large Stokes' shifts (Δλ ≈ 260 - 272 nm) by integrating the excited-state intramolecular proton transfer (ESIPT) unit 2-(2'-hydroxyphenyl)benzoxazole (HBO) into a pyridinium derived cyanine. The ESIPT not only enhances the Stokes' shifts but also improves the quantum efficiency of the probe 2 (фfl = 0.27 - 0.40 in DCM). The application of 2 in live cells imaging reveals that compound 2 stains mitochondria in eukaryotic cells, normal human lungs fibroblast (NHLF), Zebrafish's neuromast hair cells, and support cells, and inner plasma membrane in prokaryotic cells, Escherichia coli (E. coli).
journal_name
Dyes Pigmjournal_title
Dyes and pigments : an international journalauthors
Dahal D,Ojha KR,Pokhrel S,Paruchuri S,Konopka M,Liu Q,Pang Ydoi
10.1016/j.dyepig.2021.109629keywords:
["ESIPT","fluorescence imaging","mitochondria","near-infrared","neuromast","plasma membrane"]subject
Has Abstractpub_date
2021-10-01 00:00:00eissn
0143-7208issn
1873-3743journal_volume
194pub_type
杂志文章相关文献
文献大全abstract::The ongoing pandemic of coronavirus disease 2019 (COVID-19) posed a major challenge to the public health. Currently, no proven antiviral treatment for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection is available. Here we report compounds pentalysine β-carbonylphthalocyanine zinc (ZnPc5K) and chl...
journal_title:Dyes and pigments : an international journal
pub_type: 杂志文章
doi:10.1016/j.dyepig.2021.109570
更新日期:2021-10-01 00:00:00