Tumor vascularity predicts recurrence in differentiated thyroid carcinoma.

Abstract:

BACKGROUND:New prognosticators are necessary for optimizing the extent of thyroidectomy and adjuvant radiotherapy in differentiated thyroid carcinoma. METHODS:Tumor microvessel density (MVD), expression of thymidine phosphorylase (dThdPase) and CD68 stained macrophages were evaluated in 71 differentiated thyroid carcinomas by an immunohistochemical method. RESULTS:The recurrence-free survival was significantly (P <0.05) shorter in patients with hypervascular tumors but was not related to the dThdPase expression. Significant (R = 0.323, P <0.001) correlation between dThdPase expression score and increment in MVD was documented. Frequent high MVD and dThdPase expression were encountered in tumors >3 cm. Twenty-two of the 27 (82%) patients expressing high dThdPase were also evaluated positive for CD68 (P <0.001). CONCLUSIONS:Tumor MVD might be a new prognostic indicator of differentiated thyroid carcinoma, whereas dThdpase expression with high MVD might serve to identify a subgroup of thyroid carcinoma patients as potential candidates for adjuvant radiotherapy.

journal_name

Am J Surg

authors

Dhar DK,Kubota H,Kotoh T,Tabara H,Watanabe R,Tachibana M,Kohno H,Nagasue N

doi

10.1016/s0002-9610(98)00238-4

subject

Has Abstract

pub_date

1998-11-01 00:00:00

pages

442-7

issue

5

eissn

0002-9610

issn

1879-1883

pii

S0002961098002384

journal_volume

176

pub_type

杂志文章
  • Income, productivity, and satisfaction of breast surgeons.

    abstract:BACKGROUND:The purpose of this study was to assess how the practice patterns of breast surgeons affect their income and job satisfaction. METHODS:A 19-question survey regarding practice patterns and income and job satisfaction was mailed to all active US members of the American Society of Breast Surgeons. RESULTS:The...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2009.09.006

    authors: Bendorf DC,Helmer SD,Osland JS,Tenofsky PL

    更新日期:2010-03-01 00:00:00

  • Pancreatic enzyme levels in bile of patients with extrahepatic biliary tract disease.

    abstract::A total of ninety three patients with biliary tract disease were studied to determine the concentration of the pancreatic enzymes, amylase and lipase, in bile obtained from the gallbladder and/or common bile duct. Of seventy gallbladder bile samples, amylase levels were higher than actual or predicted serum levels in ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(79)90055-2

    authors: Anderson MC,Hauman RL,Suriyapa C,Schiller WR

    更新日期:1979-03-01 00:00:00

  • Incidence of and risk factors for anastomotic leakage after laparoscopic anterior resection with intracorporeal rectal transection and double-stapling technique anastomosis for rectal cancer.

    abstract:BACKGROUND:Laparoscopic rectal cancer surgery involving rectal division with intracorporeal stapling devices is technically difficult. This study aimed to identify risk factors for anastomotic leakage associated with laparoscopic anterior resection for rectal cancer. METHODS:We studied 363 patients who underwent lapar...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2010.11.014

    authors: Akiyoshi T,Ueno M,Fukunaga Y,Nagayama S,Fujimoto Y,Konishi T,Kuroyanagi H,Yamaguchi T

    更新日期:2011-09-01 00:00:00

  • Techniques of parathyroid exploration at North American endocrine surgery fellowship programs: what the next generation is being taught.

    abstract:BACKGROUND:Minimally invasive techniques are now often used to treat primary hyperparathyroidism but with uncertain conformity and some controversy. Endocrine surgery fellowships (ESFPs) have recently proliferated. METHODS:The directors of the 19 ESFPs recognized by the American Association of Endocrine Surgeons were ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2013.05.012

    authors: Wang TS,Pasieka JL,Carty SE

    更新日期:2014-04-01 00:00:00

  • An ideal operation for diverticulitis of the colon.

    abstract::A review has been made of the records of 208 patients operated on for complications of diverticulitis of the colon. One hundred forty patients had emergency operations and 68, elective operations. Resection and anastomosis, with or without temporary diverting colostomy, practiced in the majority of emergency cases in ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(87)90605-2

    authors: Gregg RO

    更新日期:1987-03-01 00:00:00

  • Gastric lymphoma: a clinicopathologic reappraisal.

    abstract::Histologic material from 42 cases diagnosed as gastric lymphoma at Hartford Hospital was reviewed, confirming the diagnosis in 37. Three cases of pseudolymphoma were found. The incidence of gastric lymphoma has increased steadily over the past 50 years: 35 percent of cases occurred during the past decade. Most patient...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(82)90194-5

    authors: Orlando R 3rd,Pastuszak W,Preissler PL,Welch JP

    更新日期:1982-04-01 00:00:00

  • Surgical management of renal cell carcinoma with inferior vena cava tumor thrombus.

    abstract:BACKGROUND:The successful excision of a renal cell carcinoma (RCC) invading the inferior vena cava (IVC) remains a technical intraoperative challenge and requires a careful preoperative surgical management planning. Although a radical operation remains the mainstay of the therapy for RCC, the optimal management of the ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(02)00782-1

    authors: Kaplan S,Ekici S,Doğan R,Demircin M,Ozen H,Paşaoğlu I

    更新日期:2002-03-01 00:00:00

  • Increased expression of alpha-1-antitrypsin, glutathione S-transferase pi and vascular endothelial growth factor in human pancreatic adenocarcinoma.

    abstract:BACKGROUND:This study was designed to investigate abnormalities in gene expression in ductal adenocarcinoma of the pancreas using cDNA arrays. METHODS:Gene expression in pancreatic ductal adenocarcinoma was compared with normal pancreatic tissue controls. Specimens from 5 patients with pancreatic adenocarcinoma were t...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(02)01105-4

    authors: Trachte AL,Suthers SE,Lerner MR,Hanas JS,Jupe ER,Sienko AE,Adesina AM,Lightfoot SA,Brackett DJ,Postier RG

    更新日期:2002-12-01 00:00:00

  • Lymph node staging in patients with clinically negative neck examinations by ultrasound and ultrasound-guided aspiration cytology.

    abstract::To assess the usefulness of ultrasound and ultrasound-guided fine-needle aspiration cytology in detecting occult cervical lymph node metastases, 107 patients with squamous cell carcinoma of the head and neck, who underwent 132 elective neck dissections, had preoperative ultrasound examination. During the assessment of...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(91)90149-8

    authors: van den Brekel MW,Stel HV,Castelijns JA,Croll GJ,Snow GB

    更新日期:1991-10-01 00:00:00

  • Stapled hemorrhoidopexy height as outcome indicator.

    abstract:BACKGROUND:Postoperative expectations after stapled hemorrhoidopexy are still being clarified. Our purpose was to evaluate how outcome is affected by staple line height (SLH) above the dentate line and specimen histology. METHODS:A prospective database identified demographics, SLH, histology, narcotic use, return to w...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2006.09.015

    authors: Williams R,Kondylis L,Geisler D,Kondylis P

    更新日期:2007-03-01 00:00:00

  • Perineal sinus after removal of the rectum. Occlusion with fibrin adhesive.

    abstract::Ten patients with a discharging perineal sinus that developed after proctectomy were treated with a new fibrin adhesive system in order to close the sinus. Four of the patients also had a fistula that extended from the sinus to the vagina. Treatment was unsuccessful in two patients: one had retained foreign bodies in ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(83)90142-3

    authors: Kirkegaard P,Madsen PV

    更新日期:1983-06-01 00:00:00

  • A nonneuronal 5-hydroxytryptamine receptor 3 induces chloride secretion in the rat distal colonic mucosa.

    abstract:BACKGROUND:The 5-HT3 receptor is a serotonin receptor believed to reside on enteric neurons. However, several studies belie an exclusive neural localization. Our hypothesis is that the 5-HT3 receptor agonist, 2-methyl-5-HT (2Me5HT), induces chloride secretion despite neural blockade, which can be blocked by a 5-HT3 rec...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2005.07.012

    authors: Day J,King B,Haque SM,Kellum JM

    更新日期:2005-11-01 00:00:00

  • The demise of primary profundaplasty.

    abstract::Although the importance of the profunda femoris artery in maintenance of lower extremity integrity was recognized in the earliest days of modern vascular surgery, disappointment with the performance of primary profundaplasty has emerged fully only in recent years. During the 10 year period from 1977 to 1987, only 17 p...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(88)80371-4

    authors: Harward TR,Bergan JJ,Yao JS,Flinn WR,McCarthy WJ

    更新日期:1988-08-01 00:00:00

  • Modern autotransfusion. Experience with a washed red cell processing technique.

    abstract::The technique of intraoperative autotransfusion utilizing the Haemonetics Cell Saver is described. This device separates and washes red blood cells removed from the surgical field. Advantages of this unit over others are (1) no systemic anticoagulation is required, (2) circulatory fibrin debris is removed, (3) plasma ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(81)90390-1

    authors: Sharp WV,Stark M,Donovan DL

    更新日期:1981-10-01 00:00:00

  • Does drainage of the peritoneal cavity have an impact on the postoperative course of community-acquired, secondary, lower gastrointestinal tract peritonitis?

    abstract:BACKGROUND:In the surgical management of lower gastrointestinal tract peritonitis (LGTP), drainage of the peritoneal cavity is often recommended. The objective of the study was to evaluate the impact of drainage of the abdominal cavity during management of LGTP. METHODS:From January 2009 to January 2012, patients unde...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2016.09.031

    authors: Rebibo L,Ebosse I,Iederan C,Mahjoub Y,Dupont H,Cosse C,Regimbeau JM

    更新日期:2017-07-01 00:00:00

  • Post-extubation dysphagia in trauma patients: it's hard to swallow.

    abstract:BACKGROUND:There is a significant incidence of unrecognized postextubation dysphagia in trauma patients. The purpose of this study was to evaluate the incidence, ascertain the risk factors, and identify patients with postextubation dysphagia who will require clinical swallow evaluation. METHODS:A prospective observati...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2013.08.010

    authors: Kwok AM,Davis JW,Cagle KM,Sue LP,Kaups KL

    更新日期:2013-12-01 00:00:00

  • Evaluation of breviscapine on prevention of experimentally induced abdominal adhesions in rats.

    abstract:BACKGROUND:Adhesion formation, which results from mechanical peritoneal damage, tissue ischemia, or the presence of foreign materials, is a complicated process. The formation of adhesions is associated with inflammatory response and extracellular matrix deposition in response to injury. Although the pathophysiology of ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2015.05.037

    authors: Zhang H,Song Y,Li Z,Zhang T,Zeng L

    更新日期:2016-06-01 00:00:00

  • Design and statistical methodology of the National Surgical Quality Improvement Program: why is it what it is?

    abstract::This article reviews the philosophy and principles of the National Surgical Quality Improvement Program (NSQIP) that the founders of the program had in mind when they developed the program; explains how the philosophy and principles led to the design and statistical methods that were chosen for the program; and review...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2009.07.025

    authors: Henderson WG,Daley J

    更新日期:2009-11-01 00:00:00

  • Desmoid tumors of the head and neck.

    abstract::Desmoid tumors of the head and neck are uncommon and associated with a posttreatment recurrence rate as high as 70 percent. This study was undertaken to determine cure rates achievable by surgery and radiotherapy and the factors influencing failure. A chart review of all patients at our institution with desmoid tumors...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(88)80305-2

    authors: Fasching MC,Saleh J,Woods JE

    更新日期:1988-10-01 00:00:00

  • The correlation between fundamental characteristics and first-time performance in laparoscopic tasks.

    abstract:BACKGROUND:The ability of characteristics to predict first time performance in laparoscopic tasks is not well described. Videogame experience predicts positive performance in laparoscopic experiences but its mechanism and confounding-association with aptitude remains to be elucidated. This study sought to evaluate for ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2017.04.015

    authors: Harrington CM,Bresler R,Ryan D,Dicker P,Traynor O,Kavanagh DO

    更新日期:2018-04-01 00:00:00

  • Packed red blood cell transfusion after surgery: are we "overtranfusing" our patients?

    abstract:BACKGROUND:Data on the hemoglobin (Hb) after transfusion, or the "target," which reflects the "dose" of blood given are not well studied. We sought to examine the incidence and causes of "over transfusion" of red blood cells after surgery. METHODS:Data on blood utilization including Hb triggers and targets were obtain...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2015.12.020

    authors: Lucas DJ,Ejaz A,Spolverato G,Kim Y,Gani F,Frank SM,Pawlik TM

    更新日期:2016-07-01 00:00:00

  • Strategies for building an effective mentoring relationship.

    abstract::Mentoring has been recognized as a critical aspect of the professional and/or personal development of the student, resident or faculty member. This career development resource discusses strategies for building effective mentoring relationships and outlines some of the challenges to contemporary mentoring. ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2013.08.001

    authors: Sanfey H,Hollands C,Gantt NL

    更新日期:2013-11-01 00:00:00

  • Skin-sparing mastectomy.

    abstract:BACKGROUND:Skin-sparing mastectomy represents a new surgical approach that allows a mastectomy while preserving the natural skin envelope of the breast. It facilitates immediate breast reconstruction using an implant or myocutaneous flap, resulting in excellent cosmesis. DATA SOURCES:A PubMed database literature searc...

    journal_title:American journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1016/j.amjsurg.2004.02.004

    authors: Cunnick GH,Mokbel K

    更新日期:2004-07-01 00:00:00

  • Surgical treatment of esophageal carcinoma.

    abstract::Recent progress in the surgical treatment of carcinoma of the esophagus has changed the pessimistic outlook for this malignancy. With reasonably early diagnosis, it is feasible to achieve a resectability rate of 75 to 85 percent, an operative mortality of about 5 percent and a 5 year survival rate of about 30 percent....

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(80)90386-4

    authors: Wu YK,Chen PT,Fang JP,Lin SS

    更新日期:1980-06-01 00:00:00

  • Acute diverticulitis of the right colon.

    abstract:BACKGROUND:Acute diverticulitis of the right colon is a rare condition with a higher incidence in Oriental populations than in Occidental populations. PATIENTS AND METHODS:A retrospective review was conducted between 1982 and 1993 on 22 surgically treated Chinese patients (14 men, 8 women; mean age 47 years) with docu...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/S0002-9610(97)89559-1

    authors: Lo CY,Chu KW

    更新日期:1996-02-01 00:00:00

  • Pregnancy outcomes after gastric-bypass surgery.

    abstract:BACKGROUND:The purpose of this study is to compare outcomes of patients who become pregnant within the first year after surgery and those who delayed pregnancy until after 1 year after surgery. METHODS:A retrospective review was performed to identify patients who became pregnant after their gastric-bypass surgery from...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2006.08.041

    authors: Dao T,Kuhn J,Ehmer D,Fisher T,McCarty T

    更新日期:2006-12-01 00:00:00

  • The professionalism curriculum as a cultural change agent in surgical residency education.

    abstract:BACKGROUND:Teaching professionalism effectively to fully engaged residents is a significant challenge. A key question is whether the integration of professionalism into residency education leads to a change in resident culture. METHODS:The goal of this study was to assess whether professionalism has taken root in the ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2011.05.007

    authors: Hochberg MS,Berman RS,Kalet AL,Zabar SR,Gillespie C,Pachter HL,Surgical Professionalism and Interpersonal Communications Education Study Group.

    更新日期:2012-01-01 00:00:00

  • Staging for breast carcinoma.

    abstract::Pretreatment staging and posttreatment follow-up of the breast cancer patient consists of physical examination of the breasts and regional node-bearing areas, routine laboratory studies, chest radiography, and bilateral mammography. For palpable tumors, mammography is used to determine tumor size and to identify nonpa...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(89)90539-4

    authors: Bassett LW,Giuliano AE,Gold RH

    更新日期:1989-02-01 00:00:00

  • Vertebral arteriovenous fistulas.

    abstract::Vertebral arteriovenous fistulas are rare. A report of two cases is presented with problems related to diagnosis and therapy. An alternative approach to surgical management is given. ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(79)90320-9

    authors: Quatromoni JC,Johnson JM,Wood M

    更新日期:1979-12-01 00:00:00

  • Comparative effectiveness and efficiency in peripheral vascular surgery.

    abstract:BACKGROUND:Elective peripheral vascular surgery provides quality outcomes that are of great benefit to patients, but have complications that result in severe morbidity and excessive costs. METHODS:We studied elective carotid endarterectomy, aortofemoral bypass/aortic aneurysm repairs, and femoral-distal bypass surgeri...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2010.08.025

    authors: Fry DE,Pine M,Jones BL,Meimban RJ

    更新日期:2011-03-01 00:00:00