Phylogenetic relationships and evolution of the KNOTTED class of plant homeodomain proteins.

Abstract:

:Knotted-like (KNOX) proteins constitute a group of homeodomain proteins involved in pattern formation in developing tissues of angiosperms and other green plants. We conducted phylogenetic analyses of nucleotide and amino acid sequences of all known KNOX proteins in order to examine their evolution. Our analyses reveal two groups of KNOX proteins, classes I and II. Dicot and monocot sequences occur in both classes, indicating that the protein classes arose prior to the origin of the monocots. A conifer (Picea) sequence is nested within class I, suggesting that there are likely to be other copies of KNOX genes in this and other conifers. The orthology of several grass genes (including Zea Kn1, ZMKN1) is strongly supported by phylogenetic and synteny analyses. However, no compelling evidence supports the hypothesis of orthology previously proposed for several dicot genes and ZMKN1. Analysis of expression patterns suggests that the ancestral KNOX gene was expressed in all plant parts and that the propensity to be downregulated in roots and leaves evolved in the class I genes.

journal_name

Mol Biol Evol

authors

Bharathan G,Janssen BJ,Kellogg EA,Sinha N

doi

10.1093/oxfordjournals.molbev.a026136

subject

Has Abstract

pub_date

1999-04-01 00:00:00

pages

553-63

issue

4

eissn

0737-4038

issn

1537-1719

journal_volume

16

pub_type

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