Wisconsin Card Sorting Test performance in patients with focal frontal and posterior brain damage: effects of lesion location and test structure on separable cognitive processes.

Abstract:

:Forty-six patients with single focal lesions (35 frontal, 11 nonfrontal) were administered the Wisconsin Card Sorting Test (WCST) under three conditions of test administration. The three conditions varied in the amount of external support provided via specificity of instructions. The WCST, while a multifactorial test, is specifically sensitive to the effects of frontal lobe damage if deficits in language comprehension and visual-spatial search are controlled. There is also specificity of functioning within the frontal lobes: patients with inferior medial frontal lesions, unilateral or bilateral, were not impaired on the standard measures although they had increased loss of set when informed of the sorting categories. Verbal instructions may provide a probe to improve diagnosis and prognosis, assessment of the potential efficacy of treatment, and the time frame of plasticity of specific cognitive operations.

journal_name

Neuropsychologia

journal_title

Neuropsychologia

authors

Stuss DT,Levine B,Alexander MP,Hong J,Palumbo C,Hamer L,Murphy KJ,Izukawa D

doi

10.1016/s0028-3932(99)00093-7

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

388-402

issue

4

eissn

0028-3932

issn

1873-3514

pii

S0028-3932(99)00093-7

journal_volume

38

pub_type

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