Laparoscopic bladder seromyotomy: laboratory experience.

Abstract:

:Twelve female microminipigs with normal bladder capacity underwent laparoscopic bladder seromyotomy. Three other female microminipigs were added to the study as controls. Urodynamic studies and cystograms were performed preoperatively and at 2 and 4 months after a laparoscopic bladder seromyotomy. Histologic studies of the treated bladders were performed when the animals were euthanized at 4 months. The operation was completed in all 12 test animals. There was no significant difference in bladder capacity or leak-point pressure between the 12 seromyotomy and the 3 control bladders at any time point. Histologically, over the seromyotomy site, the urothelium remained intact; however, the muscularis was attenuated, and a thin layer of fibrotic tissue replaced the normal serosal covering of the bladder. Laparoscopic bladder seromyotomy can be performed reliably in the porcine animal model. Not surprisingly, no significant changes in bladder capacity or bladder compliance were seen in our study of normal bladders. An animal model of a neuropathic contracted bladder is needed to assess more accurately the physiological impact of laparoscopic seromyotomy.

journal_name

J Endourol

journal_title

Journal of endourology

authors

Figenshau RS,Clayman RV,Klutke CG,McDougall EM,Pearle MS,Moon YT,Gardner SM,Tiemann DD

doi

10.1089/end.1996.10.267

subject

Has Abstract

pub_date

1996-06-01 00:00:00

pages

267-71

issue

3

eissn

0892-7790

issn

1557-900X

journal_volume

10

pub_type

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