Abstract:
OBJECTIVE:Intraoperative mannitol is routinely administered for renoprotection in partial nephrectomy (PN). However, there is a paucity of evidence supporting mannitol's renoprotective effect. We performed a retrospective study of mannitol's efficacy in PN. MATERIALS AND METHODS:Using an institutional database, patients undergoing PN from 2006 to 2016 were retrospectively identified and divided into two groups based on mannitol use. Cases with missing serum creatinine measurements were excluded. Mannitol use was dependent on surgeon preference. An independent-samples t-test was used to compare 6-month postoperative estimated glomerular filtration rate (eGFR) between mannitol groups and to compare 6-month eGFR between mannitol dose for patients who received mannitol. Multivariate linear regression was used to estimate 6-month eGFR when adjusting for multiple covariates that were considered clinically relevant to postoperative renal function. RESULTS:Of the patients, 476 patients were eligible for analysis and 286 received mannitol. Preoperative eGFR (7.8 ± 21.4 mL/minute/1.73 m2 vs 75.3 ± 23.1 mL/minute/1.73 m2, p = 0.223) and tumor size (3.5 ± 1.7 cm vs 3.4 ± 1.5 cm, p = 0.532) were matched between the mannitol (M+) and no mannitol (M-) groups, whereas warm ischemic time (22.5 ± 11.2 minutes vs 15.0 ± 10.2 minutes, p < 0.001) was longer in the M+ group. There was no significant difference in 6-month eGFR between mannitol groups (70.6 ± 22.2 mL/minute/1.73 m2 vs 68.0 ± 23.9 mL/minute/1.73 m2, p = 0.225). No significant association between mannitol dose and 6-month eGFR was found. Covariates that significantly predicted 6-month eGFR in our multivariate model were age (β = 0.052, p = 0.042) and preoperative eGFR (β = 0.843, p < 0.001). In addition, neither the use of renal cooling nor the surgical approach (open vs minimally invasive) was significantly associated with 6-month eGFR. CONCLUSION:Mannitol did not demonstrate renoprotective effects based on analysis of 6-month postoperative eGFR. In addition, neither the surgical approach nor the use of renal cooling significantly predicted postoperative renal function.
journal_name
J Endouroljournal_title
Journal of endourologyauthors
Cooper CA,Shum CF,Bahler CD,Sundaram CPdoi
10.1089/end.2017.0415subject
Has Abstractpub_date
2018-04-01 00:00:00pages
354-358issue
4eissn
0892-7790issn
1557-900Xjournal_volume
32pub_type
杂志文章abstract:PURPOSE:The impact of drainage type after percutaneous nephrolithotomy (PCNL) on the health-related quality of life (HRQoL) has been rarely studied. We conducted a prospective randomized study to evaluate the differences in HRQoL among patients who received different drainage types. METHODS:A total of 90 patients who ...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2017.0444
更新日期:2017-11-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and safety of retroperitoneal laparoscopic pyelolithotomy (RLP) versus percutaneous nephrolithotomy (PCNL) for large renal pelvic calculi using a randomized controlled trial. MATERIALS AND METHODS:Patients with large renal pelvic calculi were prospectively randomized using matched-pair...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2014.0064
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:During laparoscopic nephrectomy (LPN), a stapling device is often used for vascular control, especially of the renal vein. Herein, we report our experience using a polymer clip (Hem-o-lok) for routine control of the vessels during LPN in the animal and clinical setting. PATIENTS AND METHODS:Fift...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/089277904322836730
更新日期:2004-02-01 00:00:00
abstract:: Purpose: To report on the safety, technical results, and oncologic outcomes of computed tomography guided percutaneous microwave ablation of stage cT1b renal cell carcinoma. Materials and Methods: This single-center retrospecti...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2020.0382
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:To assess the safety and efficacy of conversion from pure laparoscopy to hand-assisted laparoscopy to control mild-to-moderate bleeding during renal surgery. PATIENTS AND METHODS:Between August 2006 and August 2008, we performed 94 laparoscopic nephrectomies (44 partial and 50 radical). A total of three radica...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2010.0321
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:To examine the incidence of urinary tract infection (UTI) after flexible cystoscopy (FC) and determine whether prophylactic norfloxacin reduces this incidence compared with placebo. PATIENTS AND METHODS:A double-blind trial was performed, randomizing 234 patients to either 400 mg of norfloxacin or placebo prio...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2005.19.1006
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Magnesium (Mg(2+)) has been shown to be a kidney stone inhibitor; however, the exact mechanism of its effect is unknown. Using theoretical models, the interactions of calcium and oxalate were examined in the presence of Mg(2+). METHODS:Molecular dynamics simulations were performed with NAMD and ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2013.0173
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:To assess the frequency of minimally invasive radical cystectomy (MIRC) conversion to open surgery, what factors influence conversion, whether or not the benefits of MIRC vs open radical cystectomy (ORC) persist after conversion, and compare ORC and MIRC outcomes. MATERIALS AND METHODS:We performed a retrosp...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2018.0079
更新日期:2018-06-01 00:00:00
abstract:: Introduction and Objective: Despite the adoption of robotic donor nephrectomy, the steep learning curve of robotic recipient transplantation has hindered the implementation of a complete robot-assisted kidney transplantation (RAKT). We sought to develop a high-fidelity per...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2020.0441
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Although ultrasonography-guided percutaneous nephrostomy is relatively safe, a number of factors make it challenging for inexperienced operators. A computerized needle navigation technique using tracked ultrasonography snapshots was investigated to determine whether performance of percutaneous ne...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2014.0011
更新日期:2014-09-01 00:00:00
abstract:PURPOSE:To report the use of the hand-assisted laparoscopic (HAL) technique for removal of a horseshoe kidney in a patient with autosomal dominant polycystic kidney disease (ADPKD). CASE REPORT:Hospital and outpatient records were reviewed for a 65-year-old man with end-stage renal disease secondary to ADPKD who under...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2006.20.397
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Retroperitoneoscopy is an established procedure for renal surgery. We evaluated our results with retroperitoneoscopic pyeloplasty for ureteropelvic junction (UPJ) obstruction. PATIENTS AND METHODS:In 14 female and 10 male patients, a retroperitoneoscopic pyeloplasty was performed (13 right/11 le...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2004.18.948
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Innovations in minimally invasive surgery have led to the proposal of incision-free natural orifice translumenal endoscopic surgery (NOTES). The purpose of this manuscript is to describe the initial technique of natural orifice translumenal endoscopic surgical radical prostatectomy (NOTES-RP). M...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2008.0670
更新日期:2009-04-01 00:00:00
abstract:INTRODUCTION:Double-J stents revolutionized the minimally invasive management of ureteral strictures, but have significant morbidity. We compare stent-related symptoms and quality of life between a conventional Double-J stent and a novel thermoexpandable metal segmental ureteral stent (Memokath) in patients with ureter...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2009.0318
更新日期:2010-04-01 00:00:00
abstract:: Purpose: Transparently reported, high-quality randomized controlled trials (RCTs) play a critical role in guiding evidence based clinical practice and informing evidence-based guidelines in patients with nephrolithiasis. Prior studies have found reporting quality to be low...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2019.0649
更新日期:2020-04-01 00:00:00
abstract::Endoscopic treatment of upper-tract transitional-cell carcinoma (TCC) is well established. Nevertheless, many patients still required major ablative surgery. We have applied our experience with laparoscopic nephrectomy to the performance of laparoscopic nephroureterectomy in order to make the management of upper-tract...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1998.12.139
更新日期:1998-04-01 00:00:00
abstract:: Introduction: This exploratory retrospective analysis examined any potential prognostic role of preoperative neutrophil lymphocyte ratio (NLR) for progression-free survival (PFS) and time to endoscopically verified upper tract or bladder recurrence-free survival (RFS) in u...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2020.0283
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To assess factors that affect prostate biopsy results following salvage whole gland cryoablation. PATIENTS AND METHODS:One hundred seventy-four patients underwent prostate biopsy following salvage whole gland cryoablation of the prostate in the Cryo-OnLine Database registry. Wilcoxon rank-sum and χ2 tests and ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2016.0715
更新日期:2017-05-01 00:00:00
abstract:PURPOSE:To examine the effects of antibiotic prophylaxis on postoperative infection rate in patients with negative urine cultures undergoing ureteroscopy (URS). PATIENTS AND METHODS:Using the Clinical Research Office of the Endourological Society (CROES) URS Global Study database, patients with a negative baseline uri...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2014.0470
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:To assess the current treatment of benign prostatic obstruction (BPO) in patients on ongoing oral anticoagulation (OA). METHODS:An Internet survey was sent to all active members of the Endourological Society. The survey contained 32 questions regarding transurethral treatment of BPO in patients on ongoing OA...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2016.0627
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:To assess the "body mass index" (BMI) (weight and length) of 12 flexible ureteroscopes (digital and fiber optic) along with the light cables and camera heads, to make the best use of our instruments. MATERIALS AND METHODS:Twelve different brand-new flexible ureteroscopes from four different manufacturers, al...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2017.0438
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:To evaluate prospectively the actual bladder perforation incidence during transurethral resection of bladder tumor (TURB) performed by residents and to identify possible predisposing factors to such condition. PATIENTS AND METHODS:Thirty-four patients with bladder tumor were submitted to TURB in our academic i...
journal_title:Journal of endourology
pub_type: 临床试验,杂志文章
doi:10.1089/end.2008.0406
更新日期:2009-07-01 00:00:00
abstract::The permanent Urolume Wallstent has been used for the relief of bladder outlet obstruction (BOO), detrusor-external sphincter dyssnergia (DESD), and recurrent bulbar urethral strictures. Because of its woven construction, it allows ingrowth of urothelial tissue, resulting in complete epithelialization by 6 to 12 month...
journal_title:Journal of endourology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1089/end.1997.11.477
更新日期:1997-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Calculi from patients with musculoskeletal (MS) anomalies who are largely immobile and prone to urinary infections have been traditionally composed primarily of struvite and carbonate apatite. Because of substantial improvements in the care of these patients in recent decades, stone etiology may ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2010.0698
更新日期:2011-09-01 00:00:00
abstract:INTRODUCTION:Radical prostatectomy undoubtedly causes inflammatory damage to surrounding neuromuscular tissues (i.e., bladder, urethra, and nerves) that may contribute to urinary incontinence. We report the use of local hypothermia during robot-assisted laparoscopic prostatectomy to attenuate this injury. METHODS:Regi...
journal_title:Journal of endourology
pub_type: 临床试验,杂志文章
doi:10.1089/end.2009.0411
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:A unilateral paravertebral (PVB) block with catheter can provide extendable analgesia without physiological changes. The objective of this study was to assess the efficacy of PVB bupivacaine for providing perioperative pain relief in adults undergoing percutaneous nephrolithotomy (PCNL) under gen...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2014.0179
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Extended ureteral stricture is a rare complication of renal transplantation. Its management remains challenging. The aim of our study was to report our 15 years of experience with subcutaneous pyelovesical bypass graft (SPBG) in selected renal transplant patients who presented with extended urete...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2011.0085
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Laparoscopic radical cystectomy is confined to centers where advanced laparoscopy is performed, and its role is not yet well clear. Our aim was to evaluate, through a prospective comparative study, the advantages of the laparoscopic compared with an open approach. PATIENTS AND METHODS:From Novem...
journal_title:Journal of endourology
pub_type: 临床试验,杂志文章
doi:10.1089/end.2006.0224
更新日期:2007-03-01 00:00:00
abstract:PURPOSE:To determine the extent to which radiologists and urologists can predict histology using multiphasic CT imaging. METHODS:Patients with a preoperative multiphasic CT undergoing surgery for a renal mass were identified between 2003 and 2013. Tumors >10 cm, locally advanced or metastatic disease, and patients man...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2014.0560
更新日期:2015-04-01 00:00:00
abstract:PURPOSE:The aim of this study is to assess the effectiveness, safety, and reproducibility of the micro-ureteroscopy (m-URS) in the treatment of distal ureteral stones in women. MATERIALS AND METHODS:A multicenter, prospective observational study was designed and conducted between March and December 2015. We included w...
journal_title:Journal of endourology
pub_type: 杂志文章,多中心研究
doi:10.1089/end.2016.0503
更新日期:2016-11-01 00:00:00