Abstract:
:The inoculation of L1210 or L5178Y leukaemia cells decreased the platelet count of the recipient mouse before extensive infiltration of marrow was expected by either tumour line. The decrease was more pronounced after intravenous inoculation of L1210 leukaemia than after intraperitoneal inoculation. Inoculation of L5178Y cells by both routes caused an initial decrease but the count recovered to 80% of normal before becoming markedly depressed prior to death of the host. Implantation of diffusion chambers containing L1210 cells also decreased the platelet count, which later returned to normal.
journal_name
Br J Haematoljournal_title
British journal of haematologyauthors
Hacker M,Roberts D,Jackson Cdoi
10.1111/j.1365-2141.1977.tb00608.xsubject
Has Abstractpub_date
1977-03-01 00:00:00pages
465-71issue
3eissn
0007-1048issn
1365-2141journal_volume
35pub_type
杂志文章abstract::In acute lymphoblastic leukaemia (ALL), investigation of minimal residual disease by conventional morphology and immunology fails to detect levels of residual disease of < 1 leukaemic in 10-100 normal cells. The use of polymerase chain reaction (PCR) to exploit the diversity of the complementarity determining region (...
journal_title:British journal of haematology
pub_type: 临床试验,杂志文章
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abstract::Of 125 patients aged 65 years or over, with atrial fibrillation taking warfarin for at least 12 months, with a standard deviation (SD) of prothrombin time, expressed as the International Normalized Ratio (INR) >0.5 over the previous 6 months, 40 were randomized to continue with usual clinic care and 85 to receive educ...
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journal_title:British journal of haematology
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