Abstract:
:Fifteen strains of an anaerobic, catalase-negative, gram-positive diphtheroid-shaped bacterium recovered from human sources were characterized by phenotypic and molecular chemical and molecular genetic methods. The unidentified bacterium showed some resemblance to Actinomyces species and related taxa, but biochemical testing, polyacrylamide gel electrophoresis analysis of whole-cell proteins, and amplified 16S ribosomal DNA restriction analysis indicated the strains were distinct from all currently named Actinomyces species and related taxa. Comparative 16S rRNA gene sequencing studies showed that the bacterium represents a hitherto-unknown phylogenetic line that is related to but distinct from Actinomyces, Actinobaculum, Arcanobacterium, and Mobiluncus: We propose, on the basis of phenotypic and phylogenetic evidence, that the unknown bacterium from human clinical specimens should be classified as a new genus and species, Varibaculum cambriensis gen. nov., sp. nov. The type strain of Varibaculum cambriensis sp. nov. is CCUG 44998(T) = CIP 107344(T).
journal_name
J Clin Microbioljournal_title
Journal of clinical microbiologyauthors
Hall V,Collins MD,Lawson PA,Hutson RA,Falsen E,Inganas E,Duerden Bdoi
10.1128/jcm.41.2.640-644.2003subject
Has Abstractpub_date
2003-02-01 00:00:00pages
640-4issue
2eissn
0095-1137issn
1098-660Xjournal_volume
41pub_type
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