Abstract:
OBJECTIVE:To evaluate the skeletal health, calcium, and vitamin D homeostasis of patients upon their entry to a long-term-care facility. Factors that could contribute to the risk of future osteoporotic fractures were also evaluated. DESIGN:Cross-sectional study. PATIENTS:Two hundred eighty-seven consecutive admissions were invited to participate; 109 patients were recruited into the study. MEASUREMENTS:A high prevalence of low to low-normal circulating levels of 25(OH)D was found in nursing home residents upon their admission to the nursing home, with 86% of the patients having circulating 25(OH)D levels of less than 50 nmol/L and 41% having levels below 25 nmol/L. Frankly elevated parathyroid hormone levels were found in 16% of the patients. Additionally, alkaline phosphatase and osteocalcin levels were elevated in 23% and 13% of the patients, respectively. Bone mineral measurements were in the osteoporotic range for 85% of the nursing home residents. Bone density results for females with a history of any classic osteoporotic fracture were significantly lower than for those with no fracture history (68.5 arbitrary units (AU) for those with no fracture history, 58.8 AU in those with history of hip fracture; P < 0.05). The bone mineral measurements were higher in women with adequate 25(OH)D compared with women with deficient or borderline 25(OH)D with and without fracture history. Levels of 25(OH)D were positively correlated with urine calcium/creatinine (r = .24; P = 0.03) and 1,25(OH)2D (r = .28; P = 0.01) and were negatively correlated with 1-84 PTH (r = -.24; P = 0.02). CONCLUSION:Hypovitaminosis D is prevalent among elderly patients entering a nursing home with secondary hyperparathyroidism and apparently increased bone turnover present in patients with circulating 25(OH)D levels below 50 nmol/L. Bone density measurements showed that a majority of the individuals entering a nursing home are osteoporotic. There is a positive association between 25(OH)D levels and bone mass and a negative association between 25(OH)D levels and a history of fracture.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Komar L,Nieves J,Cosman F,Rubin A,Shen V,Lindsay Rdoi
10.1111/j.1532-5415.1993.tb06452.xsubject
Has Abstractpub_date
1993-10-01 00:00:00pages
1057-64issue
10eissn
0002-8614issn
1532-5415journal_volume
41pub_type
杂志文章abstract:OBJECTIVES:To model the relative contributions of driver data and clinical judgments to clinical ratings of driver capability for a state licensing authority and to compare ratings with on-road test results. DESIGN:Retrospective, logistic regression. SETTING:Missouri Driver License Bureau. PARTICIPANTS:Adults aged 6...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.14022
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVES:To evaluate medication use, out-of-pocket spending, and medication switching during the transition period for patients dually eligible for Medicaid and Medicare (dual eligibles). DESIGN:Time-trend analysis, using segmented linear regression. SETTING:Patient-level pharmacy dispensing data from January 2005 ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2008.02025.x
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVES:To determine whether there is racial variation in hospice enrollees in rates of hospitalization and hospice disenrollment and, if so, whether systematic differences in hospice provider patterns explain the variation. DESIGN:Longitudinal cohort study. SETTING:Hospice. PARTICIPANTS:Medicare beneficiaries (N...
journal_title:Journal of the American Geriatrics Society
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doi:10.1111/jgs.15228
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVES:To identify valid tools to diagnose delirium superimposed on dementia. DESIGN:Systematic review of studies of delirium tools that explicitly included individuals with dementia. SETTING:Hospital. PARTICIPANTS:Studies were included if delirium assessment tools were validated against standard criteria, and t...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/j.1532-5415.2012.04199.x
更新日期:2012-11-01 00:00:00
abstract::A study was made of total drug usage (prescription, over-the-counter, social), health characteristics, and life satisfaction in 55 noninstitutional retired men and women whose average age was 70 years. The sample was purposively selected on the basis of involvement in peer group interaction networks. Among those using...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1979.tb03346.x
更新日期:1979-02-01 00:00:00
abstract:OBJECTIVES:To determine whether the ability to walk 400 m could be predicted from self-reported walking habits and abilities in older adults and to develop an accurate self-report measure appropriate for observational trials of mobility when functional measures are impractical to collect. DESIGN:Cross-sectional. SETT...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2004.52571.x
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVES:To elucidate the relationship between stroke and depressive symptoms and to determine whether disability or cerebrovascular risk factors mediate that relationship. DESIGN:A prospective longitudinal epidemiological survey. SETTING:The mid-Monongahela Valley, a rural, nonfarm, low-socioeconomic-status commun...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2004.52217.x
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVES:To describe the features of community-acquired pneumonia (CAP) requiring hospitalization in subjects receiving home care. DESIGN:Prospective study from November 15, 2000, to November 14, 2002. SETTING:Six hospitals in the Edmonton, Canada, area. PARTICIPANTS:Two thousand four hundred sixty-four subjects a...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2005.53264.x
更新日期:2005-05-01 00:00:00
abstract::After a 2-week washout period, 30 elderly hypertensive patients were treated with pindolol (a beta-adrenergic blocker) for 3 weeks. In 13 patients the reduction in blood pressure was satisfactory and treatment with pindolol was continued for another 4 weeks. In 17 patients the subsequent treatment was supplemented wit...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1978.tb03680.x
更新日期:1978-08-01 00:00:00
abstract:OBJECTIVES:To describe the prevalence of coexisting conditions that affect clinical decision-making in adults with coronary heart disease (CHD). DESIGN:Cross-sectional. SETTING:National Health and Nutrition Examination Survey, 1999 to 2004. PARTICIPANTS:Eight thousand six hundred fifty-four people aged 45 and older;...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2011.03391.x
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVES:To evaluate national trends in electrocardiogram (EKG) monitoring in Veterans Affairs (VA) beneficiaries prescribed high-dose citalopram before and after the 2011-12 Food and Drug Administration (FDA) safety warnings. DESIGN:Interrupted time-series analyses. SETTING:National VA healthcare system data linke...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15420
更新日期:2018-08-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1997.tb00939.x
更新日期:1997-03-01 00:00:00
abstract:OBJECTIVES:To explore how different frameworks and categories of chronic conditions impact multimorbidity (defined as two or more chronic conditions) prevalence estimates and associations with patient-important functional outcomes. DESIGN:Baseline data from a population-based cohort study. SETTING:National sample of ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15921
更新日期:2019-08-01 00:00:00
abstract::While skin tears are a common occurrence in the institutionalized elderly population, nothing has been written about this problem. We retrospectively studied all incident reports during a 1-year period at a large, urban, long-term-care facility to identify residents with skin tears. The overall incidence of skin tears...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1991.tb03599.x
更新日期:1991-06-01 00:00:00
abstract:OBJECTIVES:To determine the effects of cognitive training on cognitive abilities and everyday function over 10 years. DESIGN:Ten-year follow-up of a randomized, controlled single-blind trial (Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE)) with three intervention groups and a no-contact control...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/jgs.12607
更新日期:2014-01-01 00:00:00
abstract::Two cases are reported of left atrial myxoma in elderly patients, diagnosed by combined M-mode and bidimensional echocardiography. One patient was an 80-year-old man presenting with typical signs of mitral obstruction by an atrial tumor. His symptoms were erroneously attributed to chronic bronchitis until an echocardi...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1981.tb01748.x
更新日期:1981-10-01 00:00:00
abstract::In the last decade, a new degenerative dementia, probably the second most common after Alzheimer's disease (AD), has been increasingly recognized under the consensus name of dementia with Lewy bodies (DLB). This article reviews current clinical, genetic, and pathological DLB data and indicates directions for future re...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/j.1532-5415.1998.tb06016.x
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVES:To test the effects of a communication skills training intervention on older patients' discourse during a primary care interview. DESIGN:A quasi-experimental design involving two intervention conditions. SETTING:The Family Practice Center of a university-based clinic. PARTICIPANTS:Thirty-three patients av...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2001.4911244.x
更新日期:2001-11-01 00:00:00
abstract::Clostridium difficile causes pseudomembranous colitis and is responsible for 20% to 25% of cases of postantibiotic diarrhea. In an earlier study, nursing-home patients with C. difficile infection were noted to have a high mortality rate. Because most of these infected patients had been treated with antibiotics, it was...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1990.tb03539.x
更新日期:1990-04-01 00:00:00
abstract:OBJECTIVE:To study patterns of transmission of epidemic keratoconjunctivitis (EKC) in a chronic care facility and to assess control measures and prevent future outbreaks in this setting. DESIGN:A retrospective cohort study. SETTING:A 120-bed, four-unit, skilled nursing facility. PATIENTS:Residents and employees of t...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1993.tb07299.x
更新日期:1993-11-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.14222
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVES:To investigate whether anticholinergic burden scores from nine published anticholinergic scales are associated with adverse health outcomes, including hospital admissions, hospitalizations for falls, hospital length of stay (LOS), and more visits to general practitioners (GPs). DESIGN:Pharmacoepidemiologica...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.13206
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:To determine the contribution of cognitive impairment, prefracture functional impairment, and treatment as predictors of functional status and mobility 6 months after discharge from rehabilitation for older adults with hip fracture. DESIGN:Longitudinal. SETTING:Inpatient rehabilitation units of two communi...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
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更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:There is a need to assess longitudinal trends in physical function and to understand the prevalence of physical function status in the older population using objectively measured physical function. Therefore, the primary purpose of this study was to examine longitudinal sex-specific physical function trends ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16638
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVES:To investigate the association between blood pressure and mortality in very old people. DESIGN:Population-based cohort study. SETTING:County of Västerbotten, Sweden. PARTICIPANTS:Half of all subjects aged 85 and all of those aged 90 and 95 and older (N=348) in one urban and five rural municipalities in th...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2008.01948.x
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Observation stays are increasingly common for older adults, yet little is known about the extent to which they are being used as the Centers for Medicare and Medicaid Services (CMS) originally intended for unscheduled or acute problems and whether different types of services are reflected in curre...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16441
更新日期:2020-07-01 00:00:00
abstract::The Integrated Memory Care Clinic (IMCC) is a patient-centered medical home as defined by the National Committee for Quality Assurance directed by advanced practice registered nurses (APRNs) caring for persons living with dementia (PLWD); physicians provide specialty consultation but do not direct care or care plannin...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15528
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVES:To evaluate the association between regular antiepileptic drug (AED) use and incident dementia. DESIGN:Case-control analysis. SETTING:Finnish public health register and German health insurance data. PARTICIPANTS:Individuals with dementia of any type (German data, N=20,325) and Alzheimer's disease (AD; Fin...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15358
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVES:To compare falls and fall-related injuries that a fall evaluator or hospital incident report identified with injuries identified according to discharge International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes for the same set of inpatient episodes of care. DESIGN:Pros...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12539
更新日期:2013-12-01 00:00:00
abstract::Falls are a serious, persistent problem in hospitals. Ensuring that all hospital staff have adequate knowledge of how to prevent falls is the first step in prevention. We identified validated fall prevention knowledge tests (FPKTs) and planned to conduct a systematic literature review. When the review identified a lac...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15563
更新日期:2019-01-01 00:00:00