Transfer of iron-dextran across the placenta.

Abstract:

:In pregnant mice. 55Fe-labeled iron-dextran (Imferon) is transferred across the placenta. It was detected in the bone marrow, liver, spleen and peripheral blood of the pregnant animal, as well as in the embryonic liver erythroid precursors and peripheral blood. Uptake by liver and peripheral blood cells of pregnant anemic mice and by liver erythroid precursors of anemic embryos was significantly higher than in normal control animals. Electron-microscopic examination revealed that the iron deposits in the embryonic liver erythroid precursors had the same structure as the injected Imferon.

journal_name

Acta Haematol

journal_title

Acta haematologica

authors

Djaldetti M,Notti I,Fishman P,Bessler H

doi

10.1159/000208195

subject

Has Abstract

pub_date

1975-01-01 00:00:00

pages

292-9

issue

5

eissn

0001-5792

issn

1421-9662

journal_volume

53

pub_type

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