Bilateral testicular adrenal rests after bilateral adrenalectomies in a cushingoid patient with von Hippel-Lindau disease.

Abstract:

:We report a case of bilateral testicular masses in a 25-year-old man with von Hippel-Lindau disease presenting with cushingoid symptoms. His medical history was significant for bilateral adrenalectomies secondary to pheochromocytomas, and he began steroid therapy at that time. After exhaustive endocrinologic, radiographic, and physical examinations, the testicular masses were postulated to be active adrenal rest tissue. Bilateral testicular venous sampling found elevated glucocorticoids that were responsive to dexamethasone suppression, which confirmed the testicular masses as testicular adrenal rests without the need for surgical intervention. Successful conservative management consisted of appropriate steroid manipulation and radiographic evaluation and resulted in the resolution of presenting symptoms, a decrease in size of the bilateral testicular masses, and testicular conservation in this young man.

journal_name

Urology

journal_title

Urology

authors

Weeks DC,Walther MM,Stratakis CA,Hwang JJ,Linehan WM,Phillips JL

doi

10.1016/j.urology.2004.01.023

subject

Has Abstract

pub_date

2004-05-01 00:00:00

pages

981-2

issue

5

eissn

0090-4295

issn

1527-9995

pii

S0090429504001219

journal_volume

63

pub_type

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