Neutropenic enterocolitis as a presenting complication of acute lymphoblastic leukemia: an unusual case marked by delayed perforation of the descending colon.

Abstract:

:Neutropenic enterocolitis (NE) is a life-threatening complication most commonly seen in patients receiving intensive chemotherapy for acute leukemia. The condition usually affects the terminal ileum, cecum, or ascending colon. In rare instances, NE may occur before the initiation of chemotherapy or involve more distal bowel. The authors report the case of a 2-year-old girl who had NE affecting the descending colon as a presenting complication of acute lymphoblastic leukemia. Despite aggressive medical interventions, including granulocyte infusions, she had a delayed bowel perforation that was managed successfully with surgery. This case highlights the challenges of treating patients who have NE as an initial manifestation of acute leukemia.

journal_name

J Pediatr Surg

authors

Wilson DB,Rao A,Hulbert M,Mychaliska KP,Luchtman-Jones L,Hill DA,Foglia RP

doi

10.1016/j.jpedsurg.2004.03.083

subject

Has Abstract

pub_date

2004-07-01 00:00:00

pages

e18-20

issue

7

eissn

0022-3468

issn

1531-5037

pii

S0022346804002374

journal_volume

39

pub_type

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