[Biochemical effects of potassium citrate in the treatment of calcium oxalate lithiasis].

Abstract:

:The serum and urinary biochemical changes observed one month and six months after oral potassium citrate therapy (600 mEq/day) in 119 patients with calcium oxalate calculi were compared with those of 16 untreated cases with lithiasis. The patients that received treatment were previously divided into two groups: group A comprised 61 hypocitraturic patients and group B comprised 58 patients with other urinary disorders who were normo or hypocitraturic. The urinary pH increased by approximately half a point in both treated groups. In group A calciuria increased slightly from 180 +/- 8 to 216 +/- 10 mg/24 h but remained within the normal ranges. Creatinuria, oxaluria, uricosuria and diuresis showed no changes. Citraturia increased very significantly in both groups and more markedly in the hypocitraturic group of patients (from 198 +/- 13 to 476 +/- 35 mg/24 h). The LRC (lithogenic risk coefficient = Ca/Cit x Diu) dropped by 50%. The patients tolerated the treatment regimen well; of the 119 treated patients, only 11 abandoned treatment due to GI intolerance.

journal_name

Arch Esp Urol

authors

Conte Visús A,Ibarz Servio L,Arrabal Martín M,Ibarz Navarro JM,Ruiz Marcellán FJ

subject

Has Abstract

pub_date

1994-03-01 00:00:00

pages

141-50

issue

2

eissn

0004-0614

issn

1576-8260

journal_volume

47

pub_type

临床试验,杂志文章,多中心研究,随机对照试验
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    doi:

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    doi:

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    doi:

    authors: Jiménez-Pacheco A,Lardelli Claret P,López Luque A,Lahoz-García C,Arrabal Polo MA,Nogueras Ocaña M

    更新日期:2012-06-01 00:00:00

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    doi:

    authors: López Martí E,Prats López J,Prera Vilaseca A,Combalia Soriano N

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    doi:

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    journal_title:Archivos espanoles de urologia

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    doi:

    authors: García Diez F,Fernández Fernández R,Guerreiro González R,González del Valle C

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    pub_type: 杂志文章

    doi:

    authors: López López JA

    更新日期:1979-07-01 00:00:00

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    pub_type: 杂志文章,评审

    doi:

    authors: Placer J,López MA,Raventós C,Planas J,Salvador C,Ropero J,Morote J

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    pub_type: 杂志文章

    doi:

    authors: Barrios-Arnau L,Sanchez-Llopis A,Di Capua-Sacoto C,Ponce-Blasco P,Gomila Sard B,Rodrigo-Aliaga M

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    abstract::The usefulness of external and interstitial radiotherapy in the treatment of prostatic carcinoma is well-documented. We report on our experience in 23 cases using interstitial Au-198 seed implants in combination with external radiation. The diagnostic protocol and therapeutic approach are described. Local control was ...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Pantiga RA,Grande Ventura C,Rodríguez R,Fernández García J,Castillo AF,Vivanco J

    更新日期:1989-05-01 00:00:00

  • [Aggressive fibromatosis of the penis (desmoid tumor)].

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  • [Usefulness of transurethral resection in cancer of the prostate].

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    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Rodríguez JV,Chechile G

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  • Lytic lesions in a patient with past history of renal cancer.

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    doi:

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  • [Endoscopic treatment of vesicoureteral reflux (VUR). Comparison of various substances. Long-term results].

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    pub_type: 杂志文章,评审

    doi:

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    pub_type: 杂志文章,评审

    doi:

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    doi:

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    doi:

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    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

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    pub_type: 杂志文章,评审

    doi:

    authors: Carvalhal EF,Gill IS

    更新日期:2002-07-01 00:00:00