Abstract：
:Patients who have chest pain following the use of cocaine have become more common in emergency departments throughout the United States,with approximately 6% of these patients sustaining an acute MI. The authors have described the rationale for recommending aspirin, benzodiaze-pines, and nitroglycerin as first-line treatments and calcium-channel blockade or phentolamine as possible second-line therapies and have summarized the controversies surrounding the use of fibrinolytic agents. Admission for observation is one reasonable approach to the management of the low-risk cohort. Evaluation for underlying coronary artery disease is reasonable, particularly in patients who have acute MI. Patients who do not have infarction can undergo evaluation for possible coronary artery disease on an outpatient basis. Routine interventions for secondary prophylaxis as well as cocaine rehabilitation should be used in this patient population, because the long-term prognosis seems somewhat dependent upon the ability of the patient to discontinue cocaine use.
journal_name
Cardiol Clinjournal_title
Cardiology clinicsauthors
Hollander JE,Henry TDdoi
10.1016/j.ccl.2005.09.003subject
Has Abstractpub_date
2006-02-01 00:00:00pages
103-14issue
1eissn
0733-8651issn
1558-2264pii
S0733-8651(05)00074-3journal_volume
24pub_type
杂志文章,评审abstract：:The major adaptations of the maternal cardiovascular system that progress throughout gestation may unmask previously unrecognized heart disease and result in significant morbidity and mortality. Most of these changes are almost fully reversed in the weeks and months after delivery. Hemodynamic changes during pregnancy...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ccl.2012.05.004
更新日期：2012-08-01 00:00:00
abstract：:The fundamental requirements for a meaningful biomarker have not been met in the prediction of the aneurysm trait, the progression of the aneurysm disease state, or the prevention of catastrophic aortic complications. Aortic aneurysm is a worthy opponent on all fronts, and clinicians should continue actively to evalua...
journal_title：Cardiology clinics
pub_type： 评论,杂志文章,评审
doi：10.1016/j.ccl.2010.01.018
更新日期：2010-05-01 00:00:00
abstract：:The overall management and prognosis of patients with acute myocardial infarction must take into account not only infarct size but also the site and locus of involvement as determined by electrocardiography. Transmural versus nontransmural infarction is discussed in relation to therapy and prognosis. ...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：
更新日期：1984-02-01 00:00:00
abstract：:Abnormal systolic ventricular function and persistent ischemia are sensitive indicators of poor prognosis following myocardial infarction. The use of exercise improves the utility of both radionuclide ventriculography and myocardial perfusion scintigraphy in the identification of postinfarction patients at high risk o...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：
更新日期：1984-08-01 00:00:00
abstract：:Subaortic stenosis can be a complex disease of multiple anatomic etiologies. At the core is either an elongated and narrow outflow tract as compared to normal or a fully muscle-rimmed VSD used as an intraventricular routing pathway. An array of treatment modalities is needed for an effective management strategy. ...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8651(02)00013-9
更新日期：2002-08-01 00:00:00
abstract：:Optimum arrhythmia management has evolved to couple ICD therapy with catheter ablative and drug therapy to attempt to eliminate or reduce arrhythmia risk. No longer should the clinician approach such therapy as a choice among single alternative strategies only. Optimum patient management includes not only recognition ...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8651(05)70148-x
更新日期：2000-05-01 00:00:00
abstract：:Incident heart failure and the burden of hospitalization may be demonstrating a decline. However, as the population ages, the prevalence of heart failure continues to increase. Mortality among heart failure patients is increasingly due to non-cardiovascular causes. Current evidence-based therapy for heart failure has ...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ccl.2016.12.008
更新日期：2017-05-01 00:00:00
abstract：:Percutaneous transvenous balloon mitral valvuloplasty is a well-established alternative to surgical commissurotomy for selected symptomatic patients with rheumatic mitral stenosis. This procedure normally is performed with fluoroscopic guidance; however, even the experienced operator can be misled by radiographic land...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：
更新日期：1993-08-01 00:00:00
abstract：:Dilated cardiomyopathy is a heterogeneous disease, both clinically and genetically. Two genes responsible for X-linked DCM have been identified. Five genetic loci responsible for X-linked DCM have been identified. Five genetic loci responsible for autosomal dominant DCM have also been mapped but no genes identified so...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8651(05)70037-0
更新日期：1998-11-01 00:00:00
abstract：:Despite tremendous progress made in the management of CHD, a significant number of fatal and nonfatal CHD events still occur, which leads researchers to target other modifiable risk factors for CHD including low HDL-c (high density lipoprotein cholesterol). Although the torcetrapib experience was a major blow to CETP ...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ccl.2008.06.005
更新日期：2008-11-01 00:00:00
abstract：:The number of supporters of complete arch replacement in the surgery of acute type A aortic dissection has been steadily increasing as a result of cerebral perfusion techniques that enable the extension of safe circulatory arrest time. However, there is no agreement in the surgical community on an optimal surgical app...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ccl.2010.01.007
更新日期：2010-05-01 00:00:00
abstract：:Under normal baseline conditions the unique anatomy, myocardial ultrastructure, and coronary physiology of the right ventricle (RV) reflect a high-volume low-pressure pump. Early work described the RV as a passive conduit with minimal pumping capability. It is now appreciated that through a mechanism of ventricular in...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ccl.2012.03.009
更新日期：2012-05-01 00:00:00
abstract：:The chronotropic response is the most important means by which cardiac output is increased and oxygen delivery is maintained in response to increased oxygen consumption during exercise or stress. When the chronotropic response is suboptimal or absent, exercise intolerance results. This condition, called chronotropic i...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8651(05)70132-6
更新日期：2000-02-01 00:00:00
abstract：:Ebstein anomaly is a congenital malformation involving primarily the tricuspid valve, with failure of delamination from the underlying myocardium and right ventricular myopathy. Echocardiography is diagnostic in most patients and demonstrates apical displacement of the septal leaflet and variable tethering of leaflet ...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ccl.2020.04.004
更新日期：2020-08-01 00:00:00
abstract：:Although the growing use of continuous-flow left ventricular assist devices (LVADs) has improved the survival and quality of life of patients with stage D heart failure, ischemic and hemorrhagic cerebrovascular accidents remain one of the most-feared complications of this therapy and a significant source of disability...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ccl.2018.06.007
更新日期：2018-11-01 00:00:00
abstract：:This article reviews some important aspects of driveline infection in patients under left ventricular assist device (LVAD) support, including epidemiology, causes, diagnosis, and treatment options, both medical and surgical. Focus is placed on prevention along every aspect of the process of LVAD therapy, as the author...
journal_title：Cardiology clinics
pub_type： 杂志文章
doi：10.1016/j.ccl.2011.08.004
更新日期：2011-11-01 00:00:00
abstract：:Syncope due to idiopathic AV block is characterized by: 1) ECG documentation (usually by means of prolonged ECG monitoring) of paroxysmal complete AV block with one or multiple consecutive pauses, without P-P cycle lengthening or PR interval prolongation, not triggered by atrial or ventricular premature beats nor by r...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ccl.2015.04.012
更新日期：2015-08-01 00:00:00
abstract：:Mechanical circulatory support using left ventricular assist devices (LVAD) has become an accepted mode of therapy for both bridging patients with end-stage heart failure to transplant and as a destination therapy. Right ventricular (RV) dysfunction is common after LVAD insertion and is a significant source of morbidi...
journal_title：Cardiology clinics
pub_type： 杂志文章
doi：10.1016/j.ccl.2011.08.011
更新日期：2011-11-01 00:00:00
abstract：:Ischemic heart disease remains the leading cause of death worldwide. Low-density lipoprotein cholesterol (LDL-C) has proved to have a causal relationship with atherosclerotic cardiovascular disease. Lowering LDL-C improves outcomes, although some patients continue to have residual risk of cardiovascular disease. Cardi...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ccl.2017.12.002
更新日期：2018-05-01 00:00:00
abstract：:Over the last 2 decades human immunodeficiency virus (HIV) infection has become a chronic disease requiring long-term management. Aging, antiretroviral therapy, chronic inflammation, and several other factors contribute to the increased risk of cardiovascular disease in patients infected with HIV. In low-income and mi...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ccl.2016.09.003
更新日期：2017-02-01 00:00:00
abstract：:Evaluation of mitral regurgitation (MR) severity remains complex and challenging. An integrative approach to grading MR is recommended. The use of multiple Doppler methods should be used to help discriminate between grades of severity. Importantly, MR severity should always be considered in the context of clinical dat...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ccl.2013.04.002
更新日期：2013-05-01 00:00:00
abstract：:Transesophageal echocardiography has assisted the detection of intracardiac masses and, in certain cases, aided our ability to define the specific type of mass. This technique, when coupled with three-dimensional imaging, may help to define infiltration of the wall. TEE aids in the intraoperative management of cardiac...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8651(05)70184-3
更新日期：2000-11-01 00:00:00
abstract：:There has been heightened interest in the design and role of preparticipation screening for high school and college athletes. An American Heart Association consensus panel, composed of cardiovascular specialists and other physician experts having extensive clinical experience with athletes of all ages as well as a leg...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8651(05)70353-2
更新日期：1997-08-01 00:00:00
abstract：:This article describes the background and methodology of the published studies assessing the effects of cholesterol-lowering therapy and of treatment of multiple risk factors on the progression of coronary atherosclerosis. The results are then presented, followed by a discussion of the lessons that can be learned from...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8651(05)70259-9
更新日期：1996-02-01 00:00:00
abstract：:In recent years many guidelines on the treatment of specific medical conditions have been published with the goal of advising physicians, promoting good clinical care, and achieving a degree of equity and equality in the delivery of care. Differences exist between European and American guidelines for the management of...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ccl.2007.12.015
更新日期：2008-02-01 00:00:00
abstract：:Coronary computed tomographic angiography (CTA) is a promising noninvasive tool that allows the visualization of plaque morphology. Plaques characterized by positive remodeling, low attenuation, and napkin ring circular enhancement on contrast-enhanced coronary CTA have been regarded as rupture-prone vulnerable plaque...
journal_title：Cardiology clinics
pub_type： 杂志文章
doi：10.1016/j.ccl.2011.10.002
更新日期：2012-02-01 00:00:00
abstract：:Surrogate endpoints are important for validation of mechanism, early proof of concept, and the rational design of clinical trials for regulatory approval of drugs. The recent failure of several drugs in peripheral arterial disease (PAD) and in atherosclerosis highlights the importance of understanding drug effect and ...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ccl.2011.04.002
更新日期：2011-08-01 00:00:00
abstract：:Many types of artificial sensors for adaptive-rate pacing have appeared but as yet there is no single sensor that properly reflects metabolic demand under all circumstances. Several other types of sensors are currently evaluated. Combinations of different sensors in a single unit are very promising. At present, howeve...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：
更新日期：1992-11-01 00:00:00
abstract：:Treatment of coronary bifurcation lesions represents a challenging area in interventional cardiology, but recent advances in percutaneous coronary interventions have led to a dramatic increase in the number of patients successfully treated percutaneously. When compared with nonbifurcation interventions, bifurcation in...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ccl.2006.02.003
更新日期：2006-05-01 00:00:00
abstract：:To whatever extent the improvement in symptoms and survival rendered by treatment with ACE inhibitors is attributable to their effects on the circulation and the kidneys, this benefit can be rescinded by concomitant administration of aspirin. Although some useful prostaglandin-independent actions may persist, shutting...
journal_title：Cardiology clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8651(05)70246-0
更新日期：2001-11-01 00:00:00
