Abstract:
:Locoregional recurrent and distant metastases from squamous cell carcinomas, despite multimodality therapy, remain troublesome clinical realities. Discrepancies in success rates of various surgery and radiation treatment regimens dealing with these problems are confusing to the clinician attempting to recommend the most beneficial treatments. There is a need for an experimental model to assess therapeutic effectiveness quantitatively from which guidelines for developing clinical trials may be suggested. In this study, we provide such a model. We injected DBA-2 mice with defined numbers of KLN-205 squamous carcinoma cells to obtain baseline growth characteristics; 216 animals had no previous irradiation. The remaining 131 received 30 Gy irradiation to the right leg 50 days before injection of the tumor cells. Tumor incidence, growth and number, and location of tumor metastasis were determined in both previously irradiated and nonirradiated groups. The data demonstrate a growth-retardant effect on tumor groups by the previous irradiation (tumor bed effect). The data also show that the incidence of hematogenously spread metastases was more frequent in mice in which tumors developed in previously irradiated tissue than in mice with tumors in nonirradiated tissue.
journal_name
Ann Plast Surgjournal_title
Annals of plastic surgeryauthors
Baker DG,Morgan EP,Persing JAdoi
10.1097/00000637-199508000-00010subject
Has Abstractpub_date
1995-08-01 00:00:00pages
171-7issue
2eissn
0148-7043issn
1536-3708journal_volume
35pub_type
杂志文章abstract:BACKGROUND:Clinical infection remains a significant problem in implant-based breast reconstruction and is a physical and emotional strain to the breast reconstruction patient. Bacterial strikethrough of draping and gown material is a likely source of infection. Strategies to reduce infection in implant-based breast rec...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,随机对照试验
doi:10.1097/SAP.0000000000000086
更新日期:2014-01-01 00:00:00
abstract::Using an enzyme-linked immunosorbent assay, we investigated the amount of cell surface fibronectin and the amount released to the culture medium in human skin fibroblasts during successive cultivation. Cell surface fibronectin did not show a remarkable change in quantity through early and midpassage, but it decreased ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198503000-00010
更新日期:1985-03-01 00:00:00
abstract:BACKGROUND:Historically, dissection of the temporoparietal fascia immediately above the zygomatic arch has been avoided due to the risk of transection of the temporofrontal rami of the facial nerve. METHODS:A total of 8 fresh cadaveric hemi-faces have been dissected to investigate the relationship of the temporofronta...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e318221b563
更新日期:2012-06-01 00:00:00
abstract::There are only a few reports that investigate the measurement of functional penile length and compare the methods used for this purpose. The aim of this study was to determine the correlation between the measurement techniques and to determine an appropriate method that correlates the erect state most closely. Measure...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200204000-00008
更新日期:2002-04-01 00:00:00
abstract::The development of sophisticated bariatric surgery techniques has led to an increasing number of patients demanding a complexity of body contouring procedures that can be achieved either with a step-by-step approach or by combining dermolipectomy in various regions. The aim of this study was to test the hypothesis tha...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.SAP.0000070644.58346.4A
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:With the continued application of fat grafting in plastic surgery, many studies have focused on various factors to improve maintenance of the fat graft volume, such as platelet-rich plasma, adipose-derived stromal/stem cells, and the stromal vascular fraction (SVF). In addition, many review ar...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001589
更新日期:2018-09-01 00:00:00
abstract::Finding an appropriate soft-tissue grafting material to close a wound located over the distal phalanx of the thumb, especially the pulp region, can be a difficult task. A sensate first dorsal metacarpal artery flap, mobilized from the dorsum of the adjacent index finger and used as an island pedicle skin flap, can be ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000137134.15728.dd
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:Whether postoperative care in the intensive care unit (ICU) is a necessity for patients undergoing head and neck free flap reconstruction remains debatable. In August 2012, our institute initiated a policy to care for these patients in the ICU, opposed to the previous policy of care in the ward. Thus, we use...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001301
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:This report summarizes our experience in the management of extratemporal facial paralysis with a variety of reconstructive techniques and explores those parameters which are considered to be useful in achieving better outcomes. METHODS:In all, 56 patients with extratemporal facial paralysis were studied. All t...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3182352221
更新日期:2013-02-01 00:00:00
abstract::Radiation-induced osteosarcoma is a rare complication of radiation therapy for breast cancer. The authors present a 60-year-old patient in whom osteosarcoma of the chest wall developed 5 years after modified radical mastectomy and radiation therapy for breast cancer. One year after resection of the chest osteosarcoma,...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200203000-00016
更新日期:2002-03-01 00:00:00
abstract::This study documents that reduction mammoplasty is a procedure with excellent long-term patient satisfaction. This has not been previously well documented. One hundred nine patients after reduction mammoplasty were surveyed by questionnaire. Results of the questionnaire indicated that the majority of patients were ple...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199204000-00011
更新日期:1992-04-01 00:00:00
abstract::A simple method of grafting around draining abdominal wall fistulas is described. A Silastic sump drain stapled into a doughnut configuration is used. This produces a barrier around the fistula which drains the fluid off as it reaches the perforations of the sump drain. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198312000-00019
更新日期:1983-12-01 00:00:00
abstract::Twenty-one men with genital Paget's disease were treated in our clinic from 1968 to 1983. We report our policy regarding treatment of the clinical disorder, particularly our surgical approach. We also stress that, when considering treatment, the circumstances of the aged patients should take precedence over aggressive...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198409000-00005
更新日期:1984-09-01 00:00:00
abstract::Prosthetic vascular graft sepsis, although uncommon, can lead to catastrophic sequelae for life and limb. Axillofemoral grafts are predisposed to sepsis and perigraft seromas because of their length, subcutaneous tunneling, and infrainguinal anastomosis, and are often performed in elderly, debilitated patients. The au...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200108000-00015
更新日期:2001-08-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to establish the anatomic basis for functional upper and lower lip reconstruction with locoregional flaps. DESIGN, SETTING, AND PARTICIPANTS:This article is an anatomic fresh cadaver study. RESULTS:For lower lip reconstruction, the modified Bernard-Webster and Karapandzic flaps pre...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001642
更新日期:2019-05-01 00:00:00
abstract:INTRODUCTION:Capsular contracture after breast reconstruction is a morbid complication, occurring in 30.0% to 47.5% of patients undergoing postoperative radiotherapy. Although it is well known that radiation increases rate of capsular contracture, there are few well-established animal models that faithfully replicate s...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001362
更新日期:2018-04-01 00:00:00
abstract::A method for constructing groin flaps is presented which the author has used successfully. The flap is elevated medial to the sartorius muscle. The lateral femoral cutaneous nerve is preserved. The muscular branch is carefully divided to avoid damage to the superficial circumflex iliac artery. Near the femoral artery,...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198011000-00004
更新日期:1980-11-01 00:00:00
abstract::The experiences of the author while an Officer in the South African Medical Corps are related. During the battle of Britain he was attached to the R.A.M.C. and observed the work of pioneers in modern military plastic surgery. On his return to South Africa, he set up the Brenthurst Military Red Cross Hospital for Plast...
journal_title:Annals of plastic surgery
pub_type: 历史文章,杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::Millions of patients are treated annually in the United States with either acute or chronic wounds, costing billions of dollars. This is a retrospective study designed to quantify the directed education that medical students receive in their 4 years of training on 3 wound-related topics: physiology of tissue injury, p...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e31802dd43b
更新日期:2007-07-01 00:00:00
abstract:INTRODUCTION:Communication failures between multidisciplinary teams can impact efficiency, performance, and morale. Academic operating rooms (ORs) often have surgical, anesthesia, and nursing teams, each teaching multiple trainees. Incorrectly identifying name and "rank" (postgraduate year [PGY]) of resident trainees c...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001092
更新日期:2017-05-01 00:00:00
abstract::A new pair of forceps incorporating two skin hooks and needle driver tips on an Adson forceps frame is described. Its use, advantages, and disadvantages are outlined. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199106000-00019
更新日期:1991-06-01 00:00:00
abstract:BACKGROUND:Mesh infection after abdominal hernia repair is a devastating complication that affects general and plastic surgeons alike. The purpose of this study was 3-fold: (1) to determine current evidence for treatment of infected abdominal wall mesh via systematic review of literature, (2) to analyze our single-inst...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/SAP.0000000000001189
更新日期:2018-02-01 00:00:00
abstract::A review of the literature confirms that the brown recluse spider bite is a common and sometimes serious clinical entity. Local and systemic manifestations are extremely variable, thus complicating management of the bite. Pathophysiological studies in laboratory animals yield conflicting results and therapeutic recomm...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/00000637-198805000-00008
更新日期:1988-05-01 00:00:00
abstract::This paper studies the healing effect of recombinant human epidermal growth factor (EGF) on chronic diabetic foot ulcers. A total of 89 patients (65 male and 24 female) aged from 36 to 82 years (average of 54) enrolled for the prospective, open-label trial, crossover study. Predetermined criteria were used for diagnos...
journal_title:Annals of plastic surgery
pub_type: 临床试验,杂志文章
doi:10.1097/01.sap.0000198731.12407.0c
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:Although columellar strut grafts (CSGs) are considered among the fundamental steps for providing nasal tip support, a downward rotation of the nasal tip in patients with strut grafts can still be encountered. Patient-related factors such as nasal skin thickness can allow the plastic surgeon to anticipate cer...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001600
更新日期:2019-04-01 00:00:00
abstract::Circumcision is a commonly performed minor surgical procedure; however, it may lead to serious complications if performed by poorly trained health care providers. In this case report, a subglanular stricture causing a mushroom-like deformity resulting from circumcision is presented. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.SAP.0000024754.83430.05
更新日期:2003-02-01 00:00:00
abstract::Metacarpal fractures are a relatively common hand injury that may require operative intervention to ensure adequate reduction and stabilization. The use of permanent hardware, although acceptable, may lead to complications and an increased number of surgical procedures. The use of resorbable hardware such as poly-L-la...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200208000-00015
更新日期:2002-08-01 00:00:00
abstract::Primary cutaneous and soft tissue angiosarcoma is a rare but highly aggressive malignancy. To date, surgical resection is the mainstay of treatment, but poor prognosis is expected. To investigate whether there are factors associated with poor prognosis after surgical resection and to develop a treatment guideline for ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001004
更新日期:2017-03-01 00:00:00
abstract::Microneurovascular techniques make transfer of innervated soft tissue a reality. The present study investigated the sensory potential of four such donor sites: volar wrist, dorsal hand, dorsal foot, and great toe. Normal moving and static two-point discrimination values for these areas are reported. A sensory reeducat...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198908000-00007
更新日期:1989-08-01 00:00:00
abstract:BACKGROUND:In male-to-female genital sex reassignment surgery, the clitoris, its prepuce, and the labia minora remain among the most difficult structures to construct. We describe the authors' clitoroplasty and vulvoplasty technique. METHODS:All patients who underwent male-to-female sex reassignment surgery at a singl...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001532
更新日期:2018-10-01 00:00:00