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Toxicity of alkaline solutions.

Abstract：

:We examined the question of what determines the toxicity of alkaline solutions--pH, viscosity, or other factors. Our experiments have identified pH measurement as the simplest and most easily measured parameter for determining initial management of caustic ingestions. Viscosity is not a clinically useful measurement. The closer to 14 the pH measures, the more destructive the caustic. Non-lye solutions known to cause esophageal ulceration have a pH of 12.5 to 13.5. Most cases of deep ulceration going on to stricture formation involve lye solutions of pH 14. The critical pH that causes esophageal ulceration is 12.5, and thus a patient ingesting a substance with a pH greater than 12 should be followed closely for the possibility of esophageal ulceration.

journal_name

Ann Emerg Med

journal_title

Annals of emergency medicine

authors

Vancura EM,Clinton JE,Ruiz E,Krenzelok EP

doi

10.1016/s0196-0644(80)80264-2

subject

Has Abstract

pub_date

1980-03-01 00:00:00

pages

118-22

issue

3

eissn

0196-0644

issn

1097-6760

pii

S0196-0644(80)80264-2

journal_volume

9

pub_type

杂志文章

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