Abstract:
:Prepulse inhibition (PPI) refers to the attenuation of the amplitude of the startle reflex in response to sudden intense stimuli (pulse) if preceded by a weaker sensory stimulus (prepulse). PPI reflects the ability to filter out irrelevant information in the early stages of processing so that attention can be directed to more salient environmental features. Inhibition at this early stage of information processing appears modulated by the prefrontal cortex in a "top-down" fashion and this may account for the normal inter-individual variability in PPI and in cognitive performance. PPI data were calculated from 82 healthy male subjects who were also tested in problem solving (Stockings of Cambridge; SoC), spatial working memory (SWM) and 5-choice reaction time (RT) tests from the Cambridge Neuropsychological Test Automated Battery. Correlations between PPI scores and cognitive test variables were examined. In addition PPI scores were divided in quartiles which were used as grouping factors in examining cognitive test performance. Compared to individuals in the lowest quartile those in the highest had (a) shorter execution but not reaction times on the 5-choice RT, (b) shorter subsequent but not initial thinking times in the SoC where they also solved more problems correctly with the minimum number of moves, and (c) better strategy but not errors scores in the SWM. Our findings suggest that greater PPI is associated with superior abilities in strategy formation and execution times. We suggest that this is due to more efficient early information processing.
journal_name
Neuropsychologiajournal_title
Neuropsychologiaauthors
Bitsios P,Giakoumaki SG,Theou K,Frangou Sdoi
10.1016/j.neuropsychologia.2006.04.001subject
Has Abstractpub_date
2006-01-01 00:00:00pages
2494-9issue
12eissn
0028-3932issn
1873-3514pii
S0028-3932(06)00123-0journal_volume
44pub_type
杂志文章相关文献
NEUROPSYCHOLOGIA文献大全abstract::Functional magnetic resonance imaging (fMRI) and electrocorticography (ECoG) research have been influential in revealing the functional characteristics of category-selective responses in human ventral temporal cortex (VTC). One important, but unanswered, question is how these two types of measurements might be related...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2015.07.024
更新日期:2016-03-01 00:00:00
abstract::The left anterior temporal lobe (LATL) is robustly implicated in semantic processing by a growing body of literature. However, these results have emerged from two distinct bodies of work, addressing two different processing levels. On the one hand, the LATL has been characterized as a 'semantic hub׳ that binds feature...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2014.03.001
更新日期:2014-05-01 00:00:00
abstract::Bilinguals' ability to control which language they speak and to switch between languages may rely on neurocognitive mechanisms shared with non-linguistic task switching. However, recent studies also reveal some limitations on the extent control mechanisms are shared across domains, introducing the possibility that som...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2014.10.037
更新日期:2015-01-01 00:00:00
abstract::Neuroimaging studies show that permanent peripheral lesions such as unilateral deafness cause functional reorganization in the auditory pathways. However, functional reorganization of the auditory pathways as a result of higher-level damage or abnormalities remains poorly investigated. A relatively recent behavioural ...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2009.10.023
更新日期:2010-01-01 00:00:00
abstract::According to a longstanding view, inferior as opposed to superior parietal cortex critically contributes to the spatial attentional deficits encountered following unilateral parietal ischemic lesions. We review the evidence on which this view is based and contrast it with more recent structural lesion evidence concern...
journal_title:Neuropsychologia
pub_type: 杂志文章,评审
doi:10.1016/j.neuropsychologia.2011.12.016
更新日期:2012-05-01 00:00:00
abstract::Humans typically show left-hemisphere dominance both for language and manual gestures. If this reflects a dependence of these behaviors on a common cerebral specialization, then healthy left-handers with atypical organization of language should show a similar pattern for gesture. Consistent with this hypothesis, we re...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2011.02.044
更新日期:2011-06-01 00:00:00
abstract::It has been postulated recently that the cerebellum contributes the same prediction and learning functions to linguistic processing as it does towards motor control. For example, repetitive TMS over posterior-lateral cerebellum caused a significant loss in predictive language processing, as assessed by the latency of ...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2016.04.022
更新日期:2016-06-01 00:00:00
abstract::Brain imaging studies have suggested a predominant involvement of prefrontal areas during retrieval of information from working memory (WM). This study used event-related functional magnetic resonance imaging to assess the gradual recruitment of brain areas during verbal WM-retrieval with a parametrically varied modif...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2006.05.015
更新日期:2006-01-01 00:00:00
abstract::Recent behavioral and neuroscientific evidence speaks to the question of whether the human focus of attention is limited to a single item or can accommodate several items. This issue is fundamental to an understanding of the nature of human cognition and brain function. Here I review evidence from visual working memor...
journal_title:Neuropsychologia
pub_type: 杂志文章,评审
doi:10.1016/j.neuropsychologia.2011.01.035
更新日期:2011-05-01 00:00:00
abstract::Consciousness of the finiteness of one's personal existence influences human thoughts and behaviors tremendously. However, the neural substrates underlying the processing of death-related information remain unclear. The current study addressed this issue by scanning 20 female adults, using functional magnetic resonanc...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2010.07.026
更新日期:2010-10-01 00:00:00
abstract::Dual-process models of recognition memory distinguish between the retrieval of qualitative information about a prior event (recollection), and judgments of prior occurrence based on an acontextual sense of familiarity. fMRI studies investigating the neural correlates of memory encoding and retrieval conducted within t...
journal_title:Neuropsychologia
pub_type: 杂志文章,评审
doi:10.1016/j.neuropsychologia.2012.06.004
更新日期:2012-11-01 00:00:00
abstract::Emerging evidence from studies using, for example, acute tryptophan depletion or investigating genetic variation of genes related to the serotonin signaling pathway suggest a role of serotonin in executive functions such as top-down attention, working memory and inhibitory control. In the current study, we aimed at ex...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2011.09.038
更新日期:2011-11-01 00:00:00
abstract::Unlike taking, which can be redescribed in non-social and object-directed terms, acts of giving are invariably expressed across languages in a three-argument structure relating agent, patient, and object. Developmental evidence suggests this difference in the syntactic entailment of the patient role to be rooted in a ...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2020.107363
更新日期:2020-03-02 00:00:00
abstract::Brain activity in numerous perisylvian brain regions is modulated by the expectedness of linguistic stimuli. We leverage recent advances in computational parsing models to test what representations guide the processes reflected by this activity. Recurrent Neural Network Grammars (RNNGs) are generative models of (tree,...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2020.107479
更新日期:2020-09-01 00:00:00
abstract::Two right-handed patients with infarction involving the forebrain commissural fibres produced irregular but rapid repetitive movements with their left hands while producing normal movements with their right hands as well as having normal oral expression. The abnormality was more conspicuous when producing slow tapping...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(89)90004-3
更新日期:1989-01-01 00:00:00
abstract::Recent work has demonstrated there is a power within images to impact our later memories-an intrinsic stimulus memorability that influences memory behavior consistently across observers. This memorability is computed as explicitly reported memory performance on each image, and is significantly correlated from observer...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2020.107408
更新日期:2020-04-01 00:00:00
abstract::A classic Gestalt figure is a 4 x 4 array of items grouped by similarity into either rows or columns. We found that some people do not see rows ("row blindness"). Furthermore, row blindness correlates with difficulties processing written language--more than half of the college-age dyslexics tested were row blind. Read...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/s0028-3932(98)00028-1
更新日期:1999-03-01 00:00:00
abstract::Hemispheric differences in a negative brain potential associated with selectively attending the location and type of stimulation were investigated. The earlier portion of this negativity (between 125 and 222 msec after stimulation) was associated with attending the location of the stimulus. It was symmetrical in the c...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(82)90041-0
更新日期:1982-01-01 00:00:00
abstract::The attentional blink (AB), characterized as a failure to detect a second target following correct identification of a previous target in a rapid serial visual presentation (RSVP), has become a useful measure for investigation of the temporal dynamics of attention. In our previous work, we proposed a two-stage concurr...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2010.10.032
更新日期:2011-02-01 00:00:00
abstract:UNLABELLED:The neural correlates of response to psychosocial stress and gender differences therein are difficult to model experimentally as this type of stressor is difficult to induce in a brain imaging environment. The Trier Social Stress Test (TSST), a behavioral paradigm that reliably induces moderate levels of str...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2013.11.022
更新日期:2014-01-01 00:00:00
abstract::We conducted a functional magnetic resonance imaging (fMRI) study and a voxel-based morphometry (VBM) study to investigate the functional and structural basis of how visual search for flavor labels in packaging is influenced by the color of the packaging. The participants were cued by a flavor word before searching fo...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2019.02.013
更新日期:2019-04-01 00:00:00
abstract::The visual perception of size in different regions of external space was studied in Parkinson's disease (PD). A group of patients with worse left-sided symptoms (LPD) was compared with a group with worse right-sided symptoms (RPD) and with a group of age-matched controls on judgements of the relative height or width o...
journal_title:Neuropsychologia
pub_type: 临床试验,杂志文章
doi:10.1016/s0028-3932(02)00285-3
更新日期:2003-01-01 00:00:00
abstract::Children with closed head injuries often experience significant and persistent disruptions in their social and behavioral functioning. Studies with adults sustaining a traumatic brain injury (TBI) indicate deficits in emotion recognition and suggest that these difficulties may underlie some of the social deficits. The...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2010.05.029
更新日期:2010-08-01 00:00:00
abstract::Using whole-head magnetoencephalography (MEG), audiovisual (AV) interactions during speech perception (/ta/- and /pa/-syllables) were investigated in 20 subjects. Congruent AV events served as the 'standards' of an oddball design. The deviants encompassed incongruent /ta/-/pa/ configurations differing from the standar...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2006.09.019
更新日期:2007-03-25 00:00:00
abstract::Body ownership for an artificial hand and the perceived position of one's own hand can be manipulated in the so-called rubber hand illusion. To induce this illusion, typically an artificial hand is placed next to the participant's body and stroked in synchrony with the real hand, which is hidden from view. Our first a...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2009.10.028
更新日期:2010-02-01 00:00:00
abstract::If it can be assumed that positive affect modulates cognitive control, the underlying mechanisms remain unclear. The main aim of this study was to investigate how positive affect influences proactive and reactive modes of control and to explore the temporal dynamic of this influence, in terms of its transient and/or s...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2018.04.021
更新日期:2018-06-01 00:00:00
abstract::Previous research has consistently shown that the left parietal cortex is critical for numerical processing, but the role of the right parietal lobe has been much less clear. This study used the intraoperative cortical electrical stimulation approach to investigate neural dissociation in the right parietal cortex for ...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2011.06.015
更新日期:2011-08-01 00:00:00
abstract::Ten adults, who were blind from infancy or childhood, laterally slid a horizontal rod within a short length of pipe located at the body midline, until the rod extremities were tactually-kinesthetically judged to be equidistant from the ends of the pipe. Whereas sighted subjects normally set the left extremity of the r...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(86)90058-8
更新日期:1986-01-01 00:00:00
abstract::The effect of unilateral temporal- or frontal-lobe lesions on the capacity of short-term memory for a single pattern was explored; this measure has been designated pattern span. Pattern span was assessed under different delays and with and without distraction. Both the passage of time and presence of distraction decre...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(94)90046-9
更新日期:1994-08-01 00:00:00
abstract::Previous research has suggested a time-of-day effect for response inhibition on a task known to be dependent on frontal lobe function. We used a forced desynchronisation protocol to separate effects of circadian and sleep homeostat processes on a modified version of this task. Fourteen healthy young adults followed an...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2006.12.012
更新日期:2007-04-09 00:00:00