Mixed venous and arterial pH: a comparison during hemorrhagic shock and hypothermia.

Abstract:

:Under normal conditions a linear relationship exists between venous and arterial pH values. However, with severe metabolic and hemodynamic stress this correlation has not been established. To evaluate this relationship, nine dogs were subjected to 60 minutes of hemorrhagic shock at a mean arterial pressure of 30 mm Hg and were then resuscitated. Seven dogs were rendered hypothermic by surface cooling. Serial arterial and mixed venous samples for blood gas analysis were obtained from the femoral artery, superior vena cava (SVC), right atrium (RA), and pulmonary artery (PA). There were no statistical differences between mixed venous pH values obtained from SVC, RA, and PA during any study time. The differences between arterial and mixed venous pH (AVpH) had a significant linear relationship (r greater than 0.90, P less than 0.01). The AVpH during hypothermia was +.03 to +.04 pH units. The greatest AVpH occurred during shock, and ranged from +.08 to +.20 pH units. During recovery AVpH was intermediate at +.04 to +.13. It appears that during hemorrhagic shock and moderate hypothermia, a significant relationship persists between mixed venous and arterial pH. The mixed venous sample can be obtained from the superior vena cava, right atrium, or pulmonary artery.

journal_name

Ann Emerg Med

authors

Moore EE,Good JT

doi

10.1016/s0196-0644(82)80127-3

subject

Has Abstract

pub_date

1982-06-01 00:00:00

pages

300-2

issue

6

eissn

0196-0644

issn

1097-6760

pii

S0196-0644(82)80127-3

journal_volume

11

pub_type

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