Abstract：
:Continuous follow-up of 224 patients treated for primary invasive squamous cell carcinoma of the vulva in a 20-year period (1955 to 1975) at the Mayo Clinic resulted in the detection of recurrent (or persistent) neoplasia in 59 (26%). Rates of treatment failure increased with advancing stage of disease-from 14% for Stage I to 71% for Stage IV. The rate of local vulvar recurrence was 18%, which was about three times greater than the recurrence rates for the groin, pelvis, and distant sites. However, the 1- and 5-year survival rates of 73% and 50%, respectively, after vulvar recurrence were in sharp contrast to the corresponding rates of 34% and 10% for regional or distant recurrence. When 35 patients with central vulvar extension of disease were evaluated, groups at excessive risk for treatment failure (lesions 4 cm or larger inguinal node involvement, or both) were identified and modifications in conventional therapy applicable to these groups were considered.
journal_name
Am J Obstet Gynecoljournal_title
American journal of obstetrics and gynecologyauthors
Podratz KC,Symmonds RE,Taylor WFdoi
10.1016/0002-9378(82)90823-7subject
Has Abstractpub_date
1982-06-01 00:00:00pages
340-51issue
3eissn
0002-9378issn
1097-6868pii
0002-9378(82)90823-7journal_volume
143pub_type
杂志文章abstract：OBJECTIVE:Our purpose was to determine the threshold of metabolic acidosis at delivery associated with newborn complications. STUDY DESIGN:This study was a matched case-control study of 174 term newborn infants. Three groups defined by umbilical artery base deficit at birth were 4 to 8 mmol/L, 8 to 12 mmol/L, and 12 t...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(97)70080-2
更新日期：1997-12-01 00:00:00
abstract：OBJECTIVE:Recent developments permit the use of pulse oximetry to evaluate fetal oxygenation in labor. We tested the hypothesis that the addition of fetal pulse oximetry in the evaluation of abnormal fetal heart rate patterns in labor improves the accuracy of fetal assessment and allows safe reduction of cesarean deliv...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1067/mob.2000.110632
更新日期：2000-11-01 00:00:00
abstract：BACKGROUND:Type 2 diabetes (T2D) in lean individuals is not well studied and up to 26% of diabetes occurs in these individuals. Although the cause is not well understood, it has been primarily attributed to nutritional issues during early development. OBJECTIVE:Our objective was to develop a lean T2D model using gesta...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2016.02.004
更新日期：2016-04-01 00:00:00
abstract：:The immediate postpartum period is a critical moment for contraceptive access and an opportunity to initiate long-acting reversible contraception, which includes the insertion of an intrauterine device. The use of the intrauterine device in the postpartum period is a safe practice with few contraindications and many b...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.ajog.2018.07.013
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to compare alpha-fetoprotein, human chorionic gonadotropin, and unconjugated estriol levels in women who take protease inhibitors and those women who do not. STUDY DESIGN:This retrospective review from August 2000 to May 2003 was performed for maternal serum screen results, medi...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2004.05.046
更新日期：2004-09-01 00:00:00
abstract：:Sound pressure in amniotic fluid was created by application of either an electronic artificial larynx or a standard audiometric earphone to the abdominal surface of pregnant ewes. Sound transmission was assessed with a hydrophone placed near the ear of the fetus within the intact amnion. Sound pressures produced by th...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(88)90526-1
更新日期：1988-07-01 00:00:00
abstract：OBJECTIVE:Placenta growth factor is a potent angiogenic factor produced by the human placenta that has been implicated in the pathogenesis of preeclampsia and intrauterine growth restriction. Placenta growth factor belongs to the vascular endothelial growth factor family and is capable of inducing proliferation, migrat...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2000.107437
更新日期：2000-06-01 00:00:00
abstract：:The objective of this study was to evaluate the impact of an interdisciplinary team-training program in obstetric emergencies on identifying unsupportive institutional policies and systems-based practices. We implemented a qualitative study design with a purposive sample of interdisciplinary physicians, nurses, and an...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2011.02.022
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVE:The objective of the study was to identify prognostic and environmental factors associated with vulvar carcinoma in young women. STUDY DESIGN:This study was a review of patients younger than 45 years who were diagnosed with vulvar squamous cell carcinoma between 1994 and 2006. RESULTS:Fifty-six patients wer...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2009.01.014
更新日期：2009-06-01 00:00:00
abstract：:Endometrial biopsies at varying times in the menstrual cycle were obtained from 30 healthy women (16-41 years) to be used as controls, and 19 women (16-36 years), who wore an IUD (Mazlin spring, Lippes loop, or Birnburg bow) for from 5 months to 4 years, in order to study histological changes in the endometrium in th...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(70)90508-9
更新日期：1970-04-15 00:00:00
abstract：OBJECTIVE:The objective of the study was to characterize reports to the Vaccine Adverse Event Reporting System (VAERS) in pregnant women who received seasonal influenza vaccines to assess for potential vaccine safety concerns. STUDY DESIGN:We searched VAERS for reports of adverse events (AEs) in pregnant women who rec...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2010.08.050
更新日期：2011-02-01 00:00:00
abstract：:A case of perforation of the uterus at the time of insertion of the Birnberg bow IUD in a lactating, amenorrheic woman is presented. The patient, a 25-year-old gravida 2, had the IUD inserted 2 months after delivery. Perforation occurred at the time of insertion, causing a 2 mm puncture wound in the fundus. It appe...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(66)90480-7
更新日期：1966-01-15 00:00:00
abstract：OBJECTIVE:The aim of this study was to determine, with the use of a rat model, the expression of tumor necrosis factor (TNF)-alpha, its receptors, and TNF-alpha-converting enzyme in perinatal brain lesions of early premature neonates. STUDY DESIGN:Lipopolysaccharide (LPS) was injected intraperitoneally in pregnant rat...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2009.06.005
更新日期：2009-11-01 00:00:00
abstract：:The therapeutic effectiveness of the carbon dioxide laser was evaluated in 43 pregnant women with extensive urogenital and anal condylomas. All patients received one treatment and were followed up for an average of 9 months after delivery. Laser failures (persistent disease) and recurrences (new disease) were stratifi...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(84)80024-1
更新日期：1984-01-01 00:00:00
abstract：:Ten patients with preeclampsia were monitored with a Swan-Ganz thermodilution catheter before the start of treatment. Reference data were obtained by right-heart catheterization in four normal pregnant women. In the preeclamptic group the effects of volume expansion and vasodilatation were studied. All patients showed...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(84)90357-0
更新日期：1984-10-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to determine the reported diagnostic accuracy, the validity, and the current limitations of fetal Rh genotyping from peripheral maternal blood based on the existing English-written publications. STUDY DESIGN:A search of the English literature describing fetal RhD determination f...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,meta分析
doi：10.1016/j.ajog.2006.07.033
更新日期：2006-10-01 00:00:00
abstract：:Placenta percreta in a patient with previous pelvic irradiation has never been described. Reported is a case of placenta percreta with hemoperitoneum associated with a second-trimester incomplete abortion in a patient with previous pelvic irradiation and ovarian failure. ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(90)90018-3
更新日期：1990-05-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to measure and calculate oxygen transport variables in uncomplicated term pregnancies. STUDY DESIGN:Ten normotensive primiparous women between 36 and 38 weeks' gestation underwent pulmonary and radial arterial catheterization as part of a larger study. Seven women had studies repeat...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(99)70223-1
更新日期：1999-02-01 00:00:00
abstract：OBJECTIVE:Our purpose was to study the fetal central venous pressure waveform recorded noninvasively from the inferior vena cava in normal and complicated pregnancies by means of newly developed equipment to follow the vessel lumen diameter. STUDY DESIGN:A paired ultrasonic phase-locked loop echo tracking system with ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(95)90083-7
更新日期：1995-01-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to evaluate the effect of elevated levels of circulating estradiol on the clotting and fibrinolytic system in patients undergoing controlled ovarian hyperstimulation. STUDY DESIGN:Fifty-two patients undergoing controlled ovarian hyperstimulation with human menopausal gonadotropi...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(93)90434-k
更新日期：1993-12-01 00:00:00
abstract：OBJECTIVE:The vaginal birth after cesarean delivery rate is calculated with a denominator equal to the number of all women who give birth after a previous cesarean delivery, including those who are not candidates for a trial of labor. We evaluated the impact of adjustment for noncandidates for a trial of labor on vagin...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2000.109050
更新日期：2000-11-01 00:00:00
abstract：:Placental-related fetal growth restriction arises primarily due to deficient remodeling of the uterine spiral arteries supplying the placenta during early pregnancy. The resultant malperfusion induces cell stress within the placental tissues, leading to selective suppression of protein synthesis and reduced cell proli...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.ajog.2017.11.577
更新日期：2018-02-01 00:00:00
abstract：:Among 1,613 women studied with routine ultrasonography prior to genetic amniocentesis at Northwestern University Medical School, 25 of 26 multiple gestations were detected. Sampling of fluid from both amniotic sacs was requested by 20 women with twin gestations in which both fetuses were ultrasonographically determine...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(80)90029-0
更新日期：1980-09-15 00:00:00
abstract：OBJECTIVE:The objective of the study was to assess the prevalence of levator ani denervation and reinnervation 6 months after the first delivery. STUDY DESIGN:Ninety-six primigravida women underwent quantitative electromyography of the levator ani during the third trimester and twice postpartum. A 95% confidence inter...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2008.12.044
更新日期：2009-05-01 00:00:00
abstract：:There have been 203 copper-7 IUD insertions performed in 199 women. The data from 2,230 woman-months of use have been analyzed and compared with other published reports. The copper-7 IUD was an acceptable contraceptive method in regard to effectiveness, continuation, and lack of serious complications. ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(76)90756-0
更新日期：1976-11-01 00:00:00
abstract：:Placental steroid sulfatase deficiency is an unusual cause of low estriol production during pregnancy. Its importance lies in the differentiation of this disorder from the more ominous fetal defects that result in low estriol levels. Serum free estriol levels were found to be low or absent in a 25-year-old gravida 3, ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(76)90526-3
更新日期：1976-11-15 00:00:00
abstract：:The pre-ejection period (PEP) of the fetal cardiac cycle was studied on 22 chronically instrumented pregnant ewes. The PEP was measured from the onset of the Q wave on fetal electrocardiogram to the onset of the upstroke on the fetal arterial blood pressure curve. Lengthening of the PEP was observed in association wit...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(79)90285-0
更新日期：1979-03-01 00:00:00
abstract：OBJECTIVE:Our purpose was to investigate the safety and efficacy of a synthetic intracervical hygroscopic dilator, Dilapan (Gynotech, Inc., Middlesex, N.J.), on ripening the cervix before medically indicated induction of labor. STUDY DESIGN:Two hundred forty patients with a Bishop score of < or = 4 were prospectively ...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0002-9378(96)70264-8
更新日期：1996-07-01 00:00:00
abstract：OBJECTIVE:Our purpose was to define the proliferative response and receptor status in the mammary glands of surgically postmenopausal macaques given hormone replacement therapy, equivalent for monkeys to that given women. STUDY DESIGN:Surgically postmenopausal adult female cynomolgus macaques (Macaca fascicularis) wer...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(96)70379-4
更新日期：1996-01-01 00:00:00
abstract：:Progeny of women, whose thyroid function was studied gestationally, had psychological and/or neurologic examinations at 8 months, 4 years and 7 years of age. In more than 100 pregnancies (at least 3 per cent of total pregnancies) hypothyroxinemia occurred and was treated adequately or inadequately. Children were deliv...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1976-08-01 00:00:00
