Abstract:
:To review the literature on endovascular therapies available to clinicians to aid in the management of head, neck, and intracranial tumors. Hypervascular tumors of the head and neck region, as well as the intracranial region, are associated with large amounts of blood loss intraoperatively. Preoperative embolization of selected hypervascular tumors has been proposed in the literature as a method of reducing blood loss intraoperatively. This technique involves superselective catheterization of the feeding arteries to the tumor bed and then by infusion of embolic particles to saturate the tumor bed in the hopes of inducing necrosis. For less vascular tumors, selective infusion of chemotherapeutic agents has been reported as a method of reducing the systemic toxic effects of these medications. Endovascular therapies for hypervascular and less vascular tumors hold promise, although multicenter randomized controlled trials are required to help identify the patients that will benefit the most.
journal_name
Neurosurgeryjournal_title
Neurosurgeryauthors
Gupta R,Thomas AJ,Horowitz Mdoi
10.1227/01.NEU.0000239249.65742.1Csubject
Has Abstractpub_date
2006-11-01 00:00:00pages
S251-60; discussion S3-13issue
5 Suppl 3eissn
0148-396Xissn
1524-4040pii
00006123-200611001-00027journal_volume
59pub_type
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