Propranolol-induced hypertension in treatment of cocaine intoxication.

Abstract:

:The case of a patient with apparent cocaine toxicity and drug-mediated hypertension and tachycardia is presented. IV propranolol was used as the initial treatment for his hyperadrenergic state, resulting in a decrease in heart rate but a paroxsymal increase in blood pressure. The patient required nitroprusside for control of elevated blood pressure. A mechanism of unopposed alpha stimulation as a result of beta-2 receptor blockade is proposed, and a cautious approach to the use of propranolol in these patients is suggested.

journal_name

Ann Emerg Med

authors

Ramoska E,Sacchetti AD

doi

10.1016/s0196-0644(85)80934-3

subject

Has Abstract

pub_date

1985-11-01 00:00:00

pages

1112-3

issue

11

eissn

0196-0644

issn

1097-6760

pii

S0196-0644(85)80934-3

journal_volume

14

pub_type

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