Cefamandole levels in serum and necrotic bone.

Abstract:

:Seven patients with chronic osteomyelitis were treated by surgical debridement. Cefamandole was administered intravenously before surgery. During the debridement, cefamandole concentrations were measured in serum and necrotic bone. Although adequate levels of antibiotic were achieved in the serum, minimal or no concentration of antibiotic was found in the necrotic bone. There was only minimal penetration of cefamandole into necrotic bone.

journal_name

Clin Orthop Relat Res

authors

Perry H,Ritterbusch JK,Burdge RE,Perry CR

subject

Has Abstract

pub_date

1985-10-01 00:00:00

pages

280-3

issue

199

eissn

0009-921X

issn

1528-1132

pub_type

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