The role of candidal histolytic enzymes on denture-induced stomatitis in patients living in retirement homes.

Abstract:

MATERIAL AND METHODS:Fifty nine elders wearing complete dentures and living in retirement homes in Curitiba (southern Brazil), were divided into two groups: group #1, 26 patients with denture-induced stomatitis and group #2, 33 patients without denture-induced stomatitis. The two groups were evaluated in relation to the degree of denture-induced stomatitis, salivary fungal loads, and secretion of some histolytic enzymes. RESULTS:Patients from group #1 showed higher degrees of colonisation by Candida albicans (p = 0.031). Candida krusei, Candida tropicalis, and Candida parapsilosis were also isolated, but there were no differences between the groups (p > 0.05). Secretory aspartyl protease (Sap) and chondroitinase did not show significant differences among the isolated Candida spp. in the two groups. Phospholipase secretion rates were higher among the strains of C. albicans from group #2 (p = 0.036). The same behaviour was not detected for non-albicans Candida species. CONCLUSIONS:The results could infer that differences in the secretion rates of candidal histolytic enzymes should not be imputed as imperative for the progress of denture-induced stomatitis.

journal_name

Gerodontology

journal_title

Gerodontology

authors

Thiele MC,Carvalho Ade P,Gursky LC,Rosa RT,Samaranayake LP,Rosa EA

doi

10.1111/j.1741-2358.2008.00221.x

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

229-36

issue

4

eissn

0734-0664

issn

1741-2358

pii

GER221

journal_volume

25

pub_type

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