Systemic isotretinoin treatment of oral and cutaneous lichen planus.

Abstract:

:Lichen planus of the skin and mucous membranes may be disabling. Severe pruritus or bullous lesions may be incapacitating when they occur while erosive oral lesions may be extremely painful. Various treatment modalities have been attempted including corticosteroids (parenteral, intralesional, and topical) and photochemotherapy. Recent successful therapeutic trials of topical retinoic acid and oral etretinate have been completed. Two patients with cutaneous and severe erosive oral lichen planus unresponsive to conventional therapies responded to a trial of oral isotretinoin with prompt and successful remission of cutaneous and oral lesions. This suggests that systemic isotretinoin may have a unique position in the treatment of mucous membrane lichen planus that is refractory to conventional therapies.

journal_name

Cutis

journal_title

Cutis

authors

Woo TY

subject

Has Abstract

pub_date

1985-04-01 00:00:00

pages

385-6, 390-1, 393

issue

4

eissn

0011-4162

issn

2326-6929

journal_volume

35

pub_type

杂志文章

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