Abstract：
:Ring-necked ducks (Aythya collaris) were administered a single lead shot by gastric intubation. At weekly intervals over a 7-week period, the birds were weighed and blood samples obtained for measurement of hematocrit, free erythrocyte protoporphyrin (FEP), blood lead and delta-aminolevulinic acid dehydratase (delta-ALAD) activity. The birds were fluoroscoped weekly to ensure that the pellets had been retained. Blood lead concentrations peaked 1 week after dosing at a concentration of 7.75 micrograms/ml and then fell to control levels by Week 4. FEP concentrations in the treated ducks also peaked 1 week after dosing at levels which were roughly 1200% of control concentrations. The return of FEP concentrations to normal paralleled blood lead. ALAD activity was inhibited by approximately 85% by Week 1; however, there was a gradual but steady recovery of ALAD activity through Week 7. Four of the treated birds died within 2 to 3 weeks of lead administration. Physical signs of lead toxicity were maximal 7 to 10 days postdosing and included ataxia, loss of body weight, impaction of the upper gastrointestinal tract, and bile green diarrhea. In surviving birds, overt signs of toxicity declined with time and all birds appeared normal by Week 7.
journal_name
Environ Resjournal_title
Environmental researchauthors
Mautino M,Bell JUdoi
10.1016/s0013-9351(86)80148-7subject
Has Abstractpub_date
1986-12-01 00:00:00pages
538-45issue
2eissn
0013-9351issn
1096-0953pii
S0013-9351(86)80148-7journal_volume
41pub_type
杂志文章abstract：:Elevated exposure to arsenic disproportionately affects populations relying on private well water in the United States (US). This includes many American Indian (AI) communities where naturally occurring arsenic is often above 10 µg/L, the current US Environmental Protection Agency safety standard. The Strong Heart Wat...
journal_title：Environmental research
pub_type： 杂志文章,随机对照试验
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journal_title：Environmental research
pub_type： 杂志文章,meta分析
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pub_type： 杂志文章
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更新日期：1987-08-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
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journal_title：Environmental research
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更新日期：2019-01-01 00:00:00
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更新日期：2009-01-01 00:00:00
