Computed tomography scanning after chymopapain injection for herniated nucleus pulposus. A prospective study.

Abstract:

:Fifty consecutive patients treated with chymopapain injection for a clinical and radiographic diagnosis of herniated nucleus pulposus were evaluated prospectively. All patients had a prechymopapain computed tomography (CT) scan and a three-month postinjection CT scan. In addition, ten patients (20%) had a six-month postinjection CT scan. All scans were interpreted blindly. Only six patients (12%) had obvious changes in the size of the disc when preinjection and three-month postinjection CT scans were compared. By six months, however, seven of ten patients (70%) had obvious changes in their CT scan. Seven patients (14%) were considered chymopapain treatment failures and were later treated with surgical discectomy. Only two of these seven patients (30%) had obvious changes in their three-month CT scan. Chymopapain injection did not alter the size of the herniated portion of the disc during the first three months after chymopapain injection. A decision to operate for presumed chymopapain failure should therefore be based on clinical grounds, rather than on the three-month CT appearance of the herniated disc.

journal_name

Clin Orthop Relat Res

authors

Boumphrey FR,Bell GR,Modic M,Powers DF,Hardy WR

subject

Has Abstract

pub_date

1987-06-01 00:00:00

pages

120-3

issue

219

eissn

0009-921X

issn

1528-1132

pub_type

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