Abstract:
:Eighty-four fit, unpremedicated patients who presented for routine surgery and received a standard anaesthetic technique were allocated randomly to three equal groups. Group 1 received tubocurarine 0.05 mg/kg before induction of anaesthesia. Group 2 received soluble aspirin 600 mg orally one hour before surgery, while Group 3 received no pretreatment. Aspirin prophylaxis produced a significant reduction in the incidence of subsequent suxamethonium-induced myalgia and the improvement was similar to that achieved with tubocurarine pretreatment. Pre-operative oral administration of aspirin effectively reduces muscle pains and avoids many of the complications associated with pretreatment with non-depolarising agents.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
McLoughlin C,Nesbitt GA,Howe JPdoi
10.1111/j.1365-2044.1988.tb06689.xsubject
Has Abstractpub_date
1988-07-01 00:00:00pages
565-7issue
7eissn
0003-2409issn
1365-2044journal_volume
43pub_type
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