Abstract:
:European populations have both a particularly long history of pulmonary tuberculosis and extremely high frequencies of cystic fibrosis (CF). While carriers of the recessive gene are asymptomatic for CF disease, their fibroblasts produce excessive amounts of hyaluronic acid, whose role in successful isolation of virulent pathogens appears to be especially adaptive in host resistance to the human strain of Mycobacterium tuberculosis. CF heterozygosity may have been an adaptation to a disease environment once dominated by this infection.
journal_name
Am J Phys Anthropoljournal_title
American journal of physical anthropologyauthors
Meindl RSdoi
10.1002/ajpa.1330740104subject
Has Abstractpub_date
1987-09-01 00:00:00pages
39-45issue
1eissn
0002-9483issn
1096-8644journal_volume
74pub_type
历史文章,杂志文章abstract::The Castel di Guido site, with an estimated age of approximately 300,000 years, has yielded abundant animal remains, Acheulian stone and bone bifaces, and small tools. On the surface of the original deposit, turned over by agricultural activities, fragments of human remains were discovered between 1980 and 1986, inclu...
journal_title:American journal of physical anthropology
pub_type: 历史文章,杂志文章
doi:10.1002/ajpa.1330760205
更新日期:1988-06-01 00:00:00
abstract::Femoral head size provides important information on body size in extinct species. Although it is well-known that femoral head size is correlated with acetabular size, the precision with which femoral head size can be estimated from acetabular size has not been quantified. The availability of accurate 3D surface models...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.22591
更新日期:2014-11-01 00:00:00
abstract::Maternal reproductive investment includes both the energetic costs of gestation and lactation. For most humans, the metabolic costs of lactation will exceed those of gestation. Mothers must balance reproductive investment in any single offspring against future reproductive potential. Among mammals broadly, mothers may...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.22346
更新日期:2013-10-01 00:00:00
abstract::Weight, stature, arm circumference, and the triceps skinfold were measured in 1,410 school children, 6 through 14 years of age, from two urban colonias in the city of Oaxaca de Juarez (n = 479), and from two rural Ladino (n = 467) and two rural Zapotec (n = 464) communities in the Valley of Oaxaca in southern Mexico. ...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330540305
更新日期:1981-03-01 00:00:00
abstract::The mountain gorillas of the central Virungas have been the subject of field study for the last 30 years; however, our understanding of morbidity and mortality in these apes is limited. This paper describes pathological conditions of the skeleton and dentition of these animals and evaluates lesions in relation to beha...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330810309
更新日期:1990-03-01 00:00:00
abstract::Many studies of primate diversity and evolution rely on dental morphology for insight into diet, behavior, and phylogenetic relationships. Consequently, variation in molar cusp size has increasingly become a phenotype of interest. In 2007 we published a quantitative genetic analysis of mandibular molar cusp size varia...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.21221
更新日期:2010-06-01 00:00:00
abstract::Sexual dimorphism in primate species expresses the effects of phylogeny, life history, behavior, and ontogeny. The causes and implications of sexual dimorphism have been studied in several different primates using a variety of morphological databases such as body weight, canine length, and coat color and ornamentation...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/(SICI)1096-8644(199811)107:3<243::AID-AJPA
更新日期:1998-11-01 00:00:00
abstract::With the development of computed tomography, soft tissues and foreign body collections are distinguished with remarkable resolution. This distinction is particularly useful when examining desiccated human remains, both in construction of research strategies and when invasive procedure (i.e., traditional autopsies, nee...
journal_title:American journal of physical anthropology
pub_type: 历史文章,杂志文章
doi:10.1002/ajpa.1330550114
更新日期:1981-05-01 00:00:00
abstract::All primates regularly move within three-dimensional arboreal environments and must often climb, but little is known about the energetic costs of this critical activity. Limited previous work on the energetics of incline locomotion suggests that there may be differential selective pressures for large compared to small...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.21465
更新日期:2011-05-01 00:00:00
abstract::Members of the Cercocebus-Mandrillus clade are united by several morphological features, including expanded premolars which are argued to be associated with a preponderance of hard objects in the diet. We test the association between premolar expansion and hard object feeding by examining how different dental regions ...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.21402
更新日期:2011-01-01 00:00:00
abstract::New insights may be gleaned by taking an ontogenetic approach to investigations of adult dimorphism. Previous work in this area relied on traditional, caliper-based, morphometric methods, and produced conflicting results. This study uses a three-dimensional (3-D) approach for both local and global form comparisons of ...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.10178
更新日期:2003-05-01 00:00:00
abstract::At least 29 species of fossil primates have been referred to fruit, nectar, and/or exudate feeding dietary niches. Many studies have detailed the morphological correlates of fruit feeding in comparison to insectivory and folivory. In contrast, few studies have sought to differentiate the morphological correlates of fr...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/(SICI)1096-8644(199702)102:2<187::AID-AJPA
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVES:This research theoretically models and empirically records symphyseal surface strain during in vitro human mandibular wishboning (lateral transverse bending) in order to test one aspect of the hypothesis that the chin is an adaptive response to masticatory stresses. From a perspective of optimality, three qu...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.22863
更新日期:2016-02-01 00:00:00
abstract::Multivariate analysis of the relationship between degree of heterozygosity at four blood group loci and the morphological variability in a human population was carried out. Additionally, the possibility that dermatoglyphic patterns correlate with biochemical and anthropometric variables was also investigated. A strong...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330700211
更新日期:1986-06-01 00:00:00
abstract:OBJECTIVES:This study explores variation and trends in first molar enamel thickness and daily enamel secretion rates over a 2000 year period in Britain. METHODS:Permanent first molars (n = 89) from the Roman, Anglo-Saxon, and Medieval periods, as well as modern-day Britain, were analyzed using standard histological me...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.24026
更新日期:2020-09-01 00:00:00
abstract::We documented the spacing and distribution of perikymata on the buccal enamel surface of fossil hominin anterior teeth with reference to a sample of modern human and modern great ape teeth. A sample of 27 anterior teeth attributed to Australopithecus (5 to A. afarensis, 22 to A. africanus) and of 33 attributed to Para...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1116
更新日期:2001-11-01 00:00:00
abstract::Movements of forelimb joints and segments during walking in the brown lemur (Eulemur fulvus) were analyzed using cineradiography (150 frames/sec). Metric gait parameters, forelimb kinematics, and intralimb coordination are described. Calculation of contribution of segment displacements to stance propulsion shows that ...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/(SICI)1096-8644(200002)111:2<245::AID-AJPA
更新日期:2000-02-01 00:00:00
abstract::The basicranium has been argued to contain a strong phylogenetic signal in previous analyses of primate cranial morphology. Therefore, further study of basicranial morphology may offer new insights into controversial phylogenetic relationships within primate groups. In this study, I apply 3-D geometric morphometric te...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.21370
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:Histomorphometric studies show consistent links between physical activity patterns and the microstructure underlying the size and shape of bone. Here, we adopt a combined bone approach to explore variation in microstructure of ribs and humeri related to physical activity and historical records of manual labo...
journal_title:American journal of physical anthropology
pub_type: 历史文章,杂志文章
doi:10.1002/ajpa.23853
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVES:To determine whether (1) maximal handgrip strength (HGS) is associated with inter-island level of economic development in Vanuatu, (2) how associations between island of residence and HGS are mediated by age, sex, body size/composition, and individual sociodeomographic variation, and (3) whether HGS is predi...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.23704
更新日期:2018-12-01 00:00:00
abstract::Genealogical and gene marker data from the closely related species Macaca mulatta and Macaca fascicularis have been used to search for linkage between genes coding for the blood proteins albumin, carbonic anhydrase 1 and 2, diaphorase 1 and 2, group-specific component, glucose phosphate isomerase, hemoglobin alpha cha...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330680302
更新日期:1985-11-01 00:00:00
abstract::A novel polymerase chain reaction (PCR) primer pair was used to analyze the frequency of insertion of the first described, nonhuman, baboon-specific Alu repetitive element in populations from the Papio hamadryas anubis and the Papio hamadryas hamadryas subspecies, and from a number of anubis-hamadryas hybrids. The Alu...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/(SICI)1096-8644(199905)109:1<1::AID-AJPA1>
更新日期:1999-05-01 00:00:00
abstract::Frost (1987a) proposed an algorithm for estimating the number of missing osteons that correspond to observed osteon population densities (OPD). Such an algorithm should allow more accurate estimates of bone remodeling rates for skeletal remains for which in vivo labeling is not possible. In order to validate the algor...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330930109
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:Investigations of the human femoral bicondylar angle have largely focused on interspecific differences and intrapopulation variation. This analysis assesses the range of variation in the bicondylar angle in humans across four populations, examining the effects of population, sex and age. MATERIALS AND METHO...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.22972
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVES:The Fueguians are descendants of the first settlers of America, a 'relict' isolated geographically for 10,000 years. We compared their cranial variation with other Americans, and samples from Asia and Australia to know whether the modern extinct Fueguians can be considered Paleoamericans or not. MATERIALS A...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.23207
更新日期:2017-06-01 00:00:00
abstract::Inferred dietary preference is a major component of paleoecologies of extinct primates. Molar occlusal shape correlates with diet in living mammals, so teeth are a potentially useful structure from which to reconstruct diet in extinct taxa. We assess the efficacy of Dirichlet normal energy (DNE) calculated for molar t...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.21489
更新日期:2011-06-01 00:00:00
abstract::Predation is proposed to be one of the most important factors influencing the evolution of mammalian societies. Although predation risk is thought to influence both the behavior and grouping patterns of most diurnal primates, evidence supporting this hypothesis is still limited. The spatial and temporal patterns of mi...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.22230
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVES:Human walking involves out-of-phase axial rotations of the thorax and pelvis. It has long been believed that this rotational capability is a distinctive feature of the genus Homo. However, Thompson et al. (2015) showed that chimpanzees also counter-rotate their thorax relative to the pelvis during bipedal wa...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.24136
更新日期:2021-01-01 00:00:00
abstract::It is unclear whether earlier age at menarche is associated with higher body mass index (BMI) because they share a common genetic underpinning. We investigated the impact of single nucleotide polymorphisms (SNPs) influencing menarche timing on peripubertal BMI. For 556 Fels Longitudinal Study children (277 boys/279 gi...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.22121
更新日期:2013-01-01 00:00:00
abstract::Pliopithecinae and Crouzeliinae (Primates: Pliopithecidae) are distinguished dentally by the sharper crests, more compressed cusps, larger foveae, and narrower molars of the latter. Traditionally, such differences were qualitatively related to increased folivory in crouzeliines. This was subsequently disproved by micr...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.22299
更新日期:2013-08-01 00:00:00