Hospital incidence, management and direct cost of osteogenesis imperfecta in Spain: a retrospective database analysis.

abstract：BACKGROUND:Approximately 20-30% of Canadians suffer from chronic pain. Guidelines for the management of chronic pain support the use of controlled-release (CR) opioids to treat chronic pain. Although effective in managing chronic pain, oxycodone is associated with high rates of opioid-induced constipation (OIC). The co...

journal_title：Journal of medical economics

authors： Goeree R,Goeree J

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To estimate the cost-effectiveness of ipilimumab (3 mg/kg) compared with best supportive care (BSC) in pre-treated advanced melanoma patients. METHODS:The analysis was based on a US payer perspective and lifetime time horizon. A three-state Markov model was developed representing clinical outcomes, quality-o...

journal_title：Journal of medical economics

authors： Barzey V,Atkins MB,Garrison LP,Asukai Y,Kotapati S,Penrod JR

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To compare outcomes between patients with type 2 diabetes mellitus (T2DM) using fixed-dose combination (FDC) and loose-dose combination (LDC) products. METHODS:This retrospective cohort study used MarketScan Commercial and Medicare Supplemental data from January 1, 2009-December 31, 2013. The identified popu...

journal_title：Journal of medical economics

authors： Lokhandwala T,Smith N,Sternhufvud C,Sörstadius E,Lee WC,Mukherjee J

更新日期：2016-01-01 00:00:00

abstract：:Aims: To evaluate total costs and health consequences of a colorectal cancer (CRC) screening program with colonoscopy, fecal immunochemical tests (FIT), and expanded use of multitarget stool DNA (mt-sDNA) from the perspectives of Integrated Delivery Networks (IDNs) and payers in the United States.Materials and methods...

journal_title：Journal of medical economics

authors： Hathway JM,Miller-Wilson LA,Jensen IS,Ozbay B,Regan C,Jena AB,Weinstein MC,Parks PD

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:To compare the persistence and costs of brimonidine versus brinzolamide therapy according to data collected by the UK General Practitioner Research Database (GPRD). METHODS:Patients with diagnoses of ocular hypertension or glaucoma, or treated for glaucoma by surgery or laser therapy were identified. Selecte...

journal_title：Journal of medical economics

authors： Lafuma A,Laurendeau C,Berdeaux G

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:The only effective treatment for severe aortic stenosis (AS) is valve replacement. However, many patients with co-existing conditions are ineligible for surgical valve replacement, historically leaving medical management (MM) as the only option which has a poor prognosis. Transcatheter Aortic Valve Replacemen...

journal_title：Journal of medical economics

authors： Hancock-Howard RL,Feindel CM,Rodes-Cabau J,Webb JG,Thompson AK,Banz K

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:In the last decade, the number of new agents, including monoclonal antibodies, being developed to treat metastatic colorectal cancer (mCRC) increased rapidly. While improving outcomes, these new treatments also have distinct and known safety profiles with toxicities that may require hospitalizations. However...

journal_title：Journal of medical economics

authors： Overbeek JA,Zhao Z,van Herk-Sukel MP,Barber BL,Gao S,Herings RM

更新日期：2011-01-01 00:00:00

abstract：:Aims: Allopurinol is the most common urate lowering therapy (ULT) used to treat gout but may cause life-threatening severe cutaneous adverse reactions (SCAR) in a small number of patients. Risk of SCAR is increased for patients with the HLA-B*58:01 genotype. When alternative ULT is required, febuxostat or probenecid a...

journal_title：Journal of medical economics

authors： Pruis SL,Jeon YK,Pearce F,Thong BY,Aziz MIA

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:To assess the cost-effectiveness of insulin detemir compared with Neutral Protamine Hagedorn (NPH) insulin when initiating insulin treatment in people with type 2 diabetes mellitus (T2DM) in Denmark, Finland, Norway, and Sweden. METHODS:Efficacy and safety data were derived from a 20-week multi-centre random...

journal_title：Journal of medical economics

authors： Ridderstråle M,Jensen MM,Gjesing RP,Niskanen L

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the cost-effectiveness of biphasic insulin lispro mix 75/25 (LM75/25) and mix 50/50 (LM50/50) compared with a long-acting analog insulin (LAAI) regimen from the perspective of a US healthcare payer. METHODS:A published computer simulation model of diabetes was used to evaluate the cost-effectiven...

journal_title：Journal of medical economics

authors： Pollock RF,Curtis BH,Valentine WJ

更新日期：2012-01-01 00:00:00

abstract：:Aims: Cumulative exogenous factor VIII (FVIII) exposure is an important predictor of developing neutralizing antibodies (inhibitors) to FVIII in patients with persons with hemophilia A (PwHA). The aim of this study was to model the costs of emicizumab versus FVIII prophylaxis and total treatment costs for patients wit...

journal_title：Journal of medical economics

authors： Patel AM,Corman SL,Chaplin S,Raimundo K,Sidonio RF

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:To assess the economic impact of initial and repeat hospitalizations associated with acute coronary syndrome (ACS) over 1 year (2009). DESIGN AND METHODS:National- and state-level data on length of stay (LOS) and related charges for ACS-associated hospital admissions were assessed using two Healthcare Utiliz...

journal_title：Journal of medical economics

authors： LaMori JC,Shoheiber O,Dudash K,Crivera C,Mody SH

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Alemtuzumab and natalizumab are approved as second-line therapies for relapsing-remitting multiple sclerosis (RRMS) patients in Iran who have shown an inadequate response to other disease-modifying therapy (DMT). In the absence of head-to-head trials, evaluations based on decision analytic modeling may be a ...

journal_title：Journal of medical economics

authors： Taheri S,Sahraian MA,Yousefi N

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Biologic treatments have enhanced the treatment outcomes of patients with active ankylosing spondylitis (AS). Until recently, TNF-alpha-inhibitors have been the only biologics approved for the treatment of active AS. The objective of this study was to assess the potential financial impact of the first non-TN...

journal_title：Journal of medical economics

authors： Purmonen T,Törmälehto S,Wahlman H,Puolakka K

更新日期：2019-02-01 00:00:00

abstract：AIMS:Depression is the most frequent comorbidity reported among patients with rheumatoid arthritis (RA). Comorbid depression negatively impacts RA patients' health-related quality-of-life, physical function, mental function, mortality, and experience of pain and symptom severity. The objective of this study was to asse...

journal_title：Journal of medical economics

authors： Li N,Chan E,Peterson S

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:To carry out a cost-utility analysis comparing initial treatment with solifenacin 5 mg/day vs oxybutynin immediate-release (IR) 15 mg/day for the treatment of patients with overactive bladder (OAB) from the perspective of the U.K. National Health Service (NHS). METHODS:A Markov model with six health states w...

journal_title：Journal of medical economics

authors： Hart WM,Abrams P,Munro V,Retsa P,Nazir J

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:The economic implications from the US Medicare perspective of adopting alternative treatment strategies for acute bacterial skin and skin structure infections (ABSSSIs) are substantial. The objective of this study is to describe a modeling framework that explores the impact of decisions related to both the lo...

journal_title：Journal of medical economics

authors： Revankar N,Ward AJ,Pelligra CG,Kongnakorn T,Fan W,LaPensee KT

更新日期：2014-10-01 00:00:00

abstract：:Background: Procedural efficiencies can contribute to cost reductions in transcatheter aortic valve replacement procedures (TAVR). The objective of this study is to determine operating room (OR) variable cost per minute in endovascular TAVR procedures, in a real-world hospital setting. Methods: Using Premier data from...

journal_title：Journal of medical economics

authors： Potter BJ,Ann Thompson C

更新日期：2019-10-01 00:00:00

abstract：:Aims: To estimate the budgetary impact of providing additional reimbursement for long acting injections for schizophrenia patients in psychiatric hospital settings in Japan to improve patient outcomes in schizophrenia.Methods: Budget impact analysis of change in reimbursement policy using a prevalence-based model over...

journal_title：Journal of medical economics

authors： Kasahara-Kiritani M,Chaturvedi A,Inagaki A,Wakamatsu A,Jung W

更新日期：2020-08-01 00:00:00

abstract：AIMS:Patients with psoriasis often undergo treatment with a sequence of biologic agents because of poor/loss of response to initial therapy. With the availability of newer agents like ixekizumab and secukinumab, there is a need for cost-effectiveness analyses to better reflect current clinical practice. This study aime...

journal_title：Journal of medical economics

authors： Johansson EC,Hartz S,Kiri SH,Kumar G,Svedbom A

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To estimate direct medical costs for patients with tuberous sclerosis complex (TSC) and surgical resection of subependymal giant-cell astrocytoma (SEGA). METHODS:This retrospective cohort study selected patients who had SEGA surgery and TSC claims between 2000-2011 from three large US nationwide claims datab...

journal_title：Journal of medical economics

authors： Sun P,Liu Z,Krueger D,Kohrman M

更新日期：2015-05-01 00:00:00

abstract：:Aims: To assess rates of surgical treatment, post-surgical complications, reoperations, and reimbursement in patients with clavicle fractures and acromioclavicular (AC) dislocations. Materials and methods: This US retrospective study used data from patients with ≥1 diagnosis of clavicle fracture or AC dislocation (ind...

journal_title：Journal of medical economics

authors： Putnam M,Vanderkarr M,Nandwani P,Holy CE,Chitnis AS

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:To estimate the lifetime economic consequences of glaucoma in France. METHODS:A Markov model estimated the average discounted outcome and cost of glaucoma treatment over a patient's lifetime. Clinical states were defined as first- to fourth-line drugs, no treatment, laser therapy, surgery, blindness and deat...

journal_title：Journal of medical economics

authors： Philippe Nordmann J,Lafuma A,Berdeaux G

更新日期：2009-03-01 00:00:00

abstract：AIMS:This study analyzed discrepancies in the quantity of medical services supplied by physicians under different payment systems for patients with different health statuses and illnesses by means of a field experiment. METHODS:Based on the laboratory experiment of Heike Hennig-Schmidt, we designed a field experiment ...

journal_title：Journal of medical economics

authors： Xi X,Wang E,Lu Q,Chen P,Wo T,Tang K

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to determine the cost effectiveness (from a payer's perspective) of adding clostridial collagenase ointment (CCO) to selective debridement compared with selective debridement alone (non-CCO) in the treatment of stage IV pressure ulcers among patients identified from the US Wound ...

journal_title：Journal of medical economics

authors： Carter MJ,Gilligan AM,Waycaster CR,Schaum K,Fife CE

更新日期：2017-03-01 00:00:00

abstract：AIMS:Tuberous sclerosis complex (TSC) is a multi-organ autosomal-dominant, genetic disorder with incomplete penetrance. The multiple manifestations of TSC and impacts to numerous organ systems represent significant disease, healthcare, and treatment burden. The economic and employment burden of the disease on individua...

journal_title：Journal of medical economics

authors： Skalicky AM,Rentz AM,Liu Z,Said Q,Nakagawa JA,Frost MD,Wheless JW,Dunn DW

更新日期：2018-10-01 00:00:00

abstract：:Aims: This study aimed to examine the long-term clinical and economic burden of adults with congenital heart disease (ACHD) in Hong Kong. Methods: It retrospectively analyzed 336 consecutive ACHD patients who attended the Adult Congenital Heart Clinic between January 1, 2009 and December 31, 2014. Direct medical costs...

journal_title：Journal of medical economics

authors： Lee VWY,Yan BP,Fong TMC,Fung AKP,Cheng FWT

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate medication adherence and persistence of patients treated with Etanercept and Adalimumab for Rheumatoid Arthritis, also giving economic evaluations on therapy costs for Received Daily Dose (RDD). MATERIALS AND METHODS:This retrospective study took into account 6 years fro...

journal_title：Journal of medical economics

authors： Santoleri F,Sorice P,Lasala R,Rizzo RC,Costantini A

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:To estimate direct medical costs and resource use for commercially-insured patients within two pulmonary hypertension sub-groups: pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). RESEARCH DESIGN AND METHODS:Using a retrospective cohort design, subjects (≥18 yea...

journal_title：Journal of medical economics

authors： Said Q,Martin BC,Joish VN,Kreilick C,Mathai SC

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:Atazanavir (ATV) and darunavir (DRV) are protease inhibitors approved for HIV treatment in combination with ritonavir (/r). The objectives of this study were to compare persistence (time to treatment discontinuation/modification), adherence, and healthcare costs among patients with human immunodeficiency vir...

journal_title：Journal of medical economics

authors： Farr AM,Johnston SS,Ritchings C,Brouillette M,Rosenblatt L

更新日期：2016-01-01 00:00:00