[Prophylaxis of venous thromboembolism in orthopaedic surgery--trivial option, huge potential].

Abstract:

:Venous thromboembolism (VTE) is a common, sometimes even fatal though preventable complication after surgical interventions, especially in orthopaedic surgery. The risk can be reduced by more than 50 % by mechanical means and different anticoagulant drugs. However, only few patients receive adequate treatment. Medicamentous options are limited and somewhat difficult. Most anticoagulant substances act indirectly, therefore their efficacy can easily be impaired. For some, the pharmacokinetics are quite unfavourable. Furthermore, these drugs can cause severe adverse reactions; and since drug therapy either needs daily injections or routine blood checks, its acceptance is limited even further. Fortunately, new substances have reached phase III and will shortly be released. They have a broad therapeutic index, favourable pharmacodynamics and -kinetics and seem to cause only few adverse events. Rivaroxaban, for example, is approved for orthopaedic interventions like total hip or knee replacement. Orally administered, it interacts directly with factor Xa. It proved to be superior compared to the standard therapy with Enoxaparin, has a similar risk profile and needs no routine blood checks. The following article gives a critical survey of the problem, therapeutic options, current guidelines and new possibilities. Hopefully, these new simplified therapy options will increase the acceptance of VTE prophylaxis so that the rate of fatal complications after orthopaedic interventions can further be reduced.

journal_name

Z Orthop Unfall

authors

Saxer F,Dick W

doi

10.1055/s-0029-1186018

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

26-30

issue

1

eissn

1864-6697

issn

1864-6743

journal_volume

148

pub_type

杂志文章
  • [Current status of total hip and knee replacements in Germany - results of a nation-wide survey].

    abstract:BACKGROUND:Total hip and knee replacements are very frequently performed operative procedures in German hospitals. Despite the high number of cases, only few data on treatment procedures of the clinical routine and their impact on postoperative length of stay and clinical outcome are available. The aim of our survey wa...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章,多中心研究

    doi:10.1055/s-0034-1383023

    authors: Jaschinski T,Pieper D,Eikermann M,Steinhausen S,Linke C,Heitmann T,Pani M,Neugebauer E

    更新日期:2014-10-01 00:00:00

  • [S3 guideline. Part 2: Non-Traumatic Avascular Femoral Head Necrosis in Adults - Untreated Course and Conservative Treatment].

    abstract:BACKGROUND:In Germany there are 5000 to 7000 new cases of atraumatic avascular necrosis of the femoral head in adults per year. It occurs mostly in middle age. An increased frequency of idiopathic cases can be observed. Chemotherapy, corticoids and kidney transplants are frequently associated with the disease. In most ...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0035-1545903

    authors: Roth A,Beckmann J,Smolenski U,Fischer A,Jäger M,Tingart M,Rader C,Peters KM,Reppenhagen S,Nöth U,Heiss C,Maus U

    更新日期:2015-10-01 00:00:00

  • [Malpractice in the treatment of supracondylar humeral fractures in children - experience of the arbitration office of the Northern German Medical Boards].

    abstract:INTRODUCTION:Arbitration offices ("Schlichtungsstellen") in Germany are expert panels for the extrajudicial resolution of malpractice claims. The performance of arbitration panel proceedings ("Schlichtungsverfahren") is based on the German medical and insurance jurisdiction. In Germany, and in the United States likewis...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0030-1250487

    authors: Vinz H,Neu J,Festge OA

    更新日期:2010-12-01 00:00:00

  • [Face injury from jamming in a power-operated window of a motor vehicle: a case report].

    abstract:INTRODUCTION:Automatic power-operated windows of modern motor vehicles present a risk of injury due to jam events. CASE REPORT:A 41-year-old man suffered an injury of his gingiva upon jamming of his face between the window and seal entry. The motor vehicle window that led to the injury had no closing force restriction...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0032-1327797

    authors: Hohendorff B,Burkhart KJ,Müller LP

    更新日期:2012-12-01 00:00:00

  • [Current application of osteoporosis guidelines--expert recommendations of the German Society of Orthopaedic Surgery and Traumatology].

    abstract:AIM:As an increasing number of patients suffer from osteoporosis-related disorders worldwide, the medical as well as the socioeconomic impact of this problem is significant. Although evidence-based guidelines for diagnosis and treatment are available, their application in daily practice is insufficient. The aim of our ...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0029-1186154

    authors: Günther KP,Hofbauer L,Defer A,Dreinhöfer K,Duda G,Goldhahn J,Jakob F,Kurth A,Linde I,Raschke MJ,Rueger JM,Steinbronn R,Stroszczynski C,Unger L,Zwipp H

    更新日期:2009-09-01 00:00:00

  • [S2k-Guideline on Meniscus Diseases: from Aetiology to Scoring].

    abstract::The number of patients with meniscal injuries is increasing constantly, but the treatment algorithms are undergoing continuous change. The effects of meniscal surgery, as well as the indications for the procedure, are currently a matter of heated debate. Various German speaking associations addressing topics related t...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0042-116683

    authors: Siebert CH,Becker R,Buchner M,Förster J,Frosch KH,Losch A,Niemeyer P,Scheffler S

    更新日期:2017-04-01 00:00:00

  • [Transosseous Muscle Transfer of the Medial Head of the Gastrocnemius Muscle for Successful Therapy of Refractory Tibial Head Osteomyelitis: a Case Report].

    abstract::The primary objective of osteomyelitis treatment is disinfection. Therapies can be protracted and expensive. The basic approach is to use radical debridement with antibiotics. However, radical debridement often results in major osseous defects, so it may be necessary to restore bone structures. Several different thera...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0042-100737

    authors: La Rosa GZ,Steinhausen ES,Hax PH,Glombitza M

    更新日期:2016-04-01 00:00:00

  • [Significance of Matrix-augmented Bone Marrow Stimulation for Treatment of Cartilage Defects of the Knee: A Consensus Statement of the DGOU Working Group on Tissue Regeneration].

    abstract::Surgical principles for treatment of full-thickness cartilage defects of the knee include bone marrow stimulation techniques (i.e. arthroscopic microfracturing) and transplantation techniques (i.e. autologous chondrocyte implantation and osteochondral transplantation). On the basis of increasing scientific evidence, i...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 共识发展会议,杂志文章,评审

    doi:10.1055/a-0591-6457

    authors: Niemeyer P,Becher C,Brucker PU,Buhs M,Fickert S,Gelse K,Günther D,Kaelin R,Kreuz P,Lützner J,Nehrer S,Madry H,Marlovits S,Mehl J,Ott H,Pietschmann M,Spahn G,Tischer T,Volz M,Walther M,Welsch G,Zellner J,Zinser

    更新日期:2018-10-01 00:00:00

  • [Ceramic-on-ceramic bearings in total hip arthroplasty (THA)].

    abstract::The main reason for total hip arthroplasty (THA) revision is the wear-related aseptic loosening. Younger and active patients after total joint replacement create high demands, in particular, on the bearings. The progress, especially for alumina ceramic-on-ceramic bearings and mixed ceramics have solved many problems o...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0035-1545802

    authors: Sentürk U,Perka C

    更新日期:2015-04-01 00:00:00

  • [Significance of bone mineral density and modern cementing technique for in vitro cement penetration in total shoulder arthroplasty].

    abstract:AIM:Loosening of the glenoid component is one of the major causes of failure in total shoulder arthroplasty. Possible risk factors for loosening of cemented components include an eccentric loading, poor bone quality, inadequate cementing technique and insufficient cement penetration. The application of a modern cementi...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0030-1249986

    authors: Pape G,Raiss P,Kleinschmidt K,Schuld C,Mohr G,Loew M,Rickert M

    更新日期:2010-12-01 00:00:00

  • [Intramedullary stabilisation of displaced midshaft clavicular fractures: does the fracture pattern (simple vs. complex) influence the anatomic and functional result].

    abstract:BACKGROUND:Displaced midshaft clavicular fractures are often treated operatively. The most common way of treatment is plating. Elastic stable intramedullary nailing (ESIN) is an alternative, but seldom used. Studies showed comparable or even better results for intramedullary nailing than for plating in simple 2- or 3-f...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0034-1383206

    authors: Langenhan R,Reimers N,Probst A

    更新日期:2014-12-01 00:00:00

  • [Anatomic reconstruction of hip joint biomechanics with the bone preserving Silent Micro Hip™ prosthesis].

    abstract:BACKGROUND:The design and the surgical technique of the Silent Micro Hip™ are different compared to other hip stems due to a conical shape for fixation within the metaphyseal femur. The purpose of the present study was to evaluate hip joint biomechanics of the Silent Micro Hip™ in comparison to other implants. Implant-...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0033-1350862

    authors: Ries C,Schopf W,Dietrich F,Franke S,Jakubowitz E,Sobau C,Heisel C

    更新日期:2013-10-01 00:00:00

  • Dynamic Scoliosis Correction as Alternative Treatment for Patients with Adolescent Idiopathic Scoliosis: a Non-Fusion Surgical Technique.

    abstract::Anterior dynamic scoliosis correction is an innovative non-fusion option in the treatment of patients with severe adolescent scoliosis. Growth modulation and sometimes intraoperative curve correction is achieved by convex insertion of segmental screws and a flexible polyethylene cord. The present review analyses and d...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/a-0983-1265

    authors: Trobisch PD,Kobbe P,Baroncini A

    更新日期:2020-12-01 00:00:00

  • Classical Massage and Acupuncture in Chronic Back Pain - Non-Inferiority Randomised Trial.

    abstract:BACKGROUND:Currently, there is a need for scientific evidence on the efficacy of classical massage therapy for chronic, unspecific back pain, especially for the improvement in functional impairment and long-term pain reduction. According to the National Health Care Guidelines, classical massage for nonspecific low back...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章,随机对照试验

    doi:10.1055/a-0715-2332

    authors: Klassen E,Wiebelitz KR,Beer AM

    更新日期:2019-06-01 00:00:00

  • [Prognostic factors to assess the value of arthroscopy in gonarthrosis].

    abstract:AIM:The value of athroscopy in osteoarthritis(oa) of the knee remains uncertain. Many studies claim to prove efficacy of arthroscopy in oa of the knee, while other authors report that there is no such effect. The purpose of this study was to identify factors to predict the outcome of arthroscopy in oa of the knee. MET...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2007-965172

    authors: Mazoochian F,Pietschmann MF,Krüger-Franke M,Jansson V,Müller PE

    更新日期:2007-03-01 00:00:00

  • [Complications after hip resurfacing using the ASR prosthesis in patients with osteoarthritis].

    abstract:PURPOSE:The purpose of this study was to evaluate peri- and postoperative complications and the clinical/radiological results after hip resurfacing with the ASR prosthesis in patients with osteoarthritis. METHOD:A prospective cohort study was performed including all patients who received a hip resurfacing (ASR prosthe...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1038397

    authors: Klein M,Scherger B,Bernd H,Ostermann PA

    更新日期:2008-03-01 00:00:00

  • [Flexion contracture in haemophilic knee arthropathy--10-year follow-up after hamstring release and dorsal capsulotomy].

    abstract:INTRODUCTION:The aim of this study was to evaluate the long term results of joint preserving surgery with hamstring release and dorsal capsulotomy for the treatment of therapy resistant knee flexion contracture in patients with severe haemophilia. METHODS:16 patients having undergone hamstring release and dorsal capsu...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2007-965228

    authors: Pennekamp PH,Wallny TA,Goldmann G,Kraft CN,Berdel P,Oldenburg J,Wirtz DC

    更新日期:2007-05-01 00:00:00

  • [Postarthroscopic glenohumeral chondrolysis--are there any causal factors? Case report].

    abstract:BACKGROUND:Postarthroscopic glenohumeral chondrolysis (PAGCL) is a rare complication of shoulder arthroscopy. PAGCL describes a chondrolysis in the shoulder joint after arthroscopy mostly affecting younger patients. The process leading to chondrolysis is not known yet. MATERIAL AND METHODS:The case report describes a ...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0030-1270919

    authors: Schröter S,Lutz O,Gonser CE,Ateschrang A,Badke A,Albrecht D

    更新日期:2011-12-01 00:00:00

  • [Partial physeal growth arrest with increasing genu varum deformity caused by a cortical enchondroma--a case report].

    abstract:INTRODUCTION:Trauma or infectious diseases can cause destruction of the epiphyseal region of the knee with premature partial bridging of the physis and deviation of length and axis. There is only little information about tumorous lesions as pathogenetic factor for these deviations. We have been searching for an approac...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1038999

    authors: Niethard M,Rogalski M,Deja M,Zacher J

    更新日期:2008-11-01 00:00:00

  • [Measurement on printed paper strips or on the ultrasound device with computer assistance - which technique is more accurate in paediatric hip ultrasound?].

    abstract:AIM:Two different measurement techniques of ultrasonograms of the infant hip were evaluated with respect to reproducibility of the Graf classification and variation of α- and β-angles. MATERIAL AND METHODS:In a cross-sectional, blinded study, the hips of 207 consecutive newborn babies (101 male; 106 female) were sonog...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0031-1298348

    authors: Peterlein CD,Schüttler KF,Timmesfeld N,Lakemeier S,Görg C,Fuchs-Winkelmann S,Schofer M

    更新日期:2012-04-01 00:00:00

  • [Clinical-practical Examination in Orthopaedic Teaching: Who is the "Ideal" Examiner?]

    abstract::Background Medical curricula require an increasing amount of integrated clinical practical skills education. German medical faculties are increasingly implementing the OSCE (objective structured clinical examination) to test students' practical as well as communication skills. Teaching and assessment tools for practic...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章,随机对照试验

    doi:10.1055/s-0043-109022

    authors: Melcher P,Roth A,Ghanem M,Rotzoll D

    更新日期:2017-08-01 00:00:00

  • [The articular fracture of the lower limb].

    abstract:AIMS:The combination of a distal tibia fracture with an additional upper ankle joint injury is a challenge. Apart from various implants the intraoperative problem is the handling of these two injuries with appropriate reduction and retention. The existing and further developing soft tissue damage has to be taken into c...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1039265

    authors: Weber O,Müller MC,Goost H,Burger C,Kabir K,Wirtz D

    更新日期:2009-05-01 00:00:00

  • [Dynamic gait analysis of blocked distal tibiofibular joint following syndesmotic complex lesions].

    abstract:AIM:Dynamic gait analysis of blocked distal tibiofibular joint (TFJ) has not performed yet. This prospective study investigated patients treated for ankle fractures with combined syndesmotic complex lesions after surgery including tibiofibular positioning screw using CT data detecting fibular maltorsion and dynamic gai...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-0029-1185695

    authors: Vasarhelyi A,Lubitz J,Zeh A,Wohlrab D,Hein W,Mittlmeier T

    更新日期:2009-07-01 00:00:00

  • [Non-operative treatment for severe forms of infantile idiopathic scoliosis].

    abstract:INTRODUCTION:Infantile idiopathic scoliosis (IIS) is a rare orthopaedic condition. Braces and casts are popular options in the treatment of IIS but there is a paucity of studies commenting on the outcome of non-operative treatment. The purpose of this study was to analyse failure and success after non-operative treatme...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0031-1280330

    authors: Trobisch PD,Samdani A,O'Neil C,Betz R,Cahill P

    更新日期:2012-02-01 00:00:00

  • [Diagnostic and Treatment Strategies in Morel-Lavallee Lesions in the Spinal Column and Pelvis].

    abstract:BACKGROUND:The Morel-Lavallée lesion is one of the concomitant soft tissue lesions of pelvic fractures. Its role in spine fractures and its treatment in combination with osteosynthesis of pelvic or spine fractures have not yet been determined. The aim of this study was to analyse the best diagnostic and treatment optio...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章,评审

    doi:10.1055/a-0596-8018

    authors: Becker CA,Kammerlander C,Greiner A,Sommer F,Linhart C,Böcker W,Rubenbauer B,Weidert S

    更新日期:2018-10-01 00:00:00

  • [Introduction of a new intervertebral spacer for cervical fusion: results of a controlled animal study].

    abstract:AIM:This study investigated the fusion properties of a new intervertebral spacer that is directly fixed to the adjacent vertebrae by screws. The new spacer was compared with an identical spacer without direct fixation but with an additional plate and with an autologous bone graft. METHODS:A single-level, cervical fusi...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-2007-965798

    authors: Schreiner U,Scheller G,Chen C,Schwarz M

    更新日期:2007-11-01 00:00:00

  • [The Biological Knife II - Fracture Healing and Pharmacological Interactions].

    abstract::The reasons for delayed fracture healing or non-union formation are multifactorial. Mechanical factors are well known to influence the process of fracture healing. However, there is a lack of knowledge about the biological conditions that have to be achieved for adequate bone healing. Treatment of non-unions is still ...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0035-1546146

    authors: Garcia P,Everding J,Horn D,Holstein JH,Raschke M

    更新日期:2015-10-01 00:00:00

  • [The internet: an Orthopedist's boon or bane?].

    abstract:AIM:The Internet provides additional and nearly endless health-related information material for the patient. On the other hand, previous studies reported on the lack of quality for health-related websites, especially for message boards. A direct analysis of treatment recommendations from message board members and spine...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0030-1250525

    authors: Trobisch PD,Bharucha N

    更新日期:2011-04-01 00:00:00

  • [Conventional X-Rays of Ankle Joint Fractures in Older Patients are Not Always Predictive].

    abstract::Background: Ankle fractures are extremely common in the elderly, with an incidence of up to 39 fractures per 100,000 persons per year. We found a discrepancy between intraoperative findings and preoperative X-ray findings. It was suggested that many relevant lesions of the ankle joint in the elderly cannot be detected...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/s-0042-113879

    authors: Jubel A,Faymonville C,Andermahr J,Boxberg S,Schiffer G

    更新日期:2017-02-01 00:00:00

  • [The Foot in Language, Symbols, and Myths].

    abstract::In the history of evolution, the human foot is the youngest part of our skeleton and allows plane bipedal walking due to development of a longitudinal and transverse arch of the foot, with a stable, parallel first ray, but sacrificing the ability to grasp. Due to the loss of grasping, the hominoid mothers had to lay d...

    journal_title:Zeitschrift fur Orthopadie und Unfallchirurgie

    pub_type: 杂志文章

    doi:10.1055/a-0661-6250

    authors: Zwipp H

    更新日期:2019-02-01 00:00:00